Gene description for SNX2
Gene name
sorting nexin 2
Gene symbol
SNX2
Other names/aliases
TRG-9
Species
Homo sapiens
Database cross references - SNX2
ExoCarta
ExoCarta_6643
Entrez Gene
6643
HGNC
11173
MIM
605929
UniProt
O60749
SNX2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Thymus
23844026
Gene ontology annotations for SNX2
Experiment description of studies that identified SNX2 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SNX2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SNX1
6642
Invivo
Homo sapiens
Invitro
Homo sapiens
2
SNX2
6643
Invivo
Homo sapiens
Invitro
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
3
LEPR
3953
Invivo
Homo sapiens
Invitro
Homo sapiens
4
FNBP1
23048
Invivo
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
5
PDGFRA
Invivo
Homo sapiens
Invitro
Homo sapiens
6
ACVR1B
91
Invivo
Homo sapiens
7
INSR
3643
Invivo
Homo sapiens
Invitro
Homo sapiens
8
ACVR2B
Invitro
Homo sapiens
9
SNX4
8723
Invivo
Homo sapiens
Invitro
Homo sapiens
10
EGFR
1956
Invivo
Homo sapiens
Invitro
Homo sapiens
11
PDGFRB
5159
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
12
SNX6
58533
Invivo
Homo sapiens
Invitro
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
View the network
image/svg+xml
Pathways in which SNX2 is involved