Gene description for TREML2
Gene name triggering receptor expressed on myeloid cells-like 2
Gene symbol TREML2
Other names/aliases C6orf76
TLT-2
TLT2
dJ238O23.1
Species Homo sapiens
 Database cross references - TREML2
ExoCarta ExoCarta_79865
Vesiclepedia VP_79865
Entrez Gene 79865
HGNC 21092
MIM 609715
UniProt Q5T2D2  
 TREML2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for TREML2
Molecular Function
    protein binding GO:0005515 IPI
    signaling receptor activity GO:0038023 IBA
    signaling receptor activity GO:0038023 IDA
Biological Process
    T cell activation GO:0042110 IBA
    T cell activation GO:0042110 IDA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    cell surface GO:0009986 IBA
    cell surface GO:0009986 IDA
 Experiment description of studies that identified TREML2 in exosomes
1
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for TREML2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AXL 558
Affinity Capture-MS Homo sapiens
2 RAB6A 5870
Affinity Capture-MS Homo sapiens
3 SLC12A7 10723
Affinity Capture-MS Homo sapiens
4 UPK3BL 100134938
Affinity Capture-MS Homo sapiens
5 RHBDF2 79651
Affinity Capture-MS Homo sapiens
6 DHRS7 51635
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 LETM1 3954
Affinity Capture-MS Homo sapiens
8 CAMK1D 57118
Affinity Capture-MS Homo sapiens
9 ACVR2A  
Affinity Capture-MS Homo sapiens
10 EPHX1 2052
Affinity Capture-MS Homo sapiens
11 ZBTB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 SNX6 58533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 RDH11 51109
Affinity Capture-MS Homo sapiens
14 PDZD8 118987
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 CYP51A1 1595
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 RETSAT 54884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 HARS2 23438
Affinity Capture-MS Homo sapiens
18 KCNN4 3783
Affinity Capture-MS Homo sapiens
19 SNX2 6643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 OSMR 9180
Affinity Capture-MS Homo sapiens
21 SQLE 6713
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ALG11  
Affinity Capture-MS Homo sapiens
23 ATP2A3 489
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 ESYT1 23344
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 DNM1L 10059
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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