Gene description for TREML2
Gene name triggering receptor expressed on myeloid cells-like 2
Gene symbol TREML2
Other names/aliases C6orf76
TLT-2
TLT2
dJ238O23.1
Species Homo sapiens
 Database cross references - TREML2
ExoCarta ExoCarta_79865
Entrez Gene 79865
HGNC 21092
MIM 609715
UniProt Q5T2D2  
 TREML2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for TREML2
Molecular Function
    receptor activity GO:0004872 IDA
    protein binding GO:0005515 IPI
Biological Process
    T cell activation GO:0042110 IDA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    cell surface GO:0009986 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified TREML2 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for TREML2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TREML2 is involved
No pathways found





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