Gene description for VPS26B
Gene name vacuolar protein sorting 26 homolog B (S. pombe)
Gene symbol VPS26B
Other names/aliases Pep8b
Species Homo sapiens
 Database cross references - VPS26B
ExoCarta ExoCarta_112936
Entrez Gene 112936
HGNC 28119
MIM 610027
UniProt Q4G0F5  
 VPS26B identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for VPS26B
Molecular Function
    protein transporter activity GO:0008565 IBA
Biological Process
    retrograde transport, endosome to Golgi GO:0042147 ISS
    intracellular protein transport GO:0006886 IBA
Subcellular Localization
    early endosome GO:0005769 ISS
    cytosol GO:0005829 ISS
    intracellular membrane-bounded organelle GO:0043231 IDA
    retromer complex GO:0030904 ISS
    late endosome GO:0005770 ISS
 Experiment description of studies that identified VPS26B in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VPS26B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which VPS26B is involved
No pathways found





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