Gene description for DNAJB3
Gene name DnaJ (Hsp40) homolog, subfamily B, member 3
Gene symbol DNAJB3
Other names/aliases HCG3
Species Homo sapiens
 Database cross references - DNAJB3
ExoCarta ExoCarta_414061
Entrez Gene 414061
HGNC 32397
UniProt Q8WWF6  
 DNAJB3 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for DNAJB3
Subcellular Localization
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified DNAJB3 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for DNAJB3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EWSR1 2130
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which DNAJB3 is involved
No pathways found





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