Gene description for SNRNP70
Gene name small nuclear ribonucleoprotein 70kDa (U1)
Gene symbol SNRNP70
Other names/aliases RNPU1Z
RPU1
SNRP70
Snp1
U1-70K
U170K
U1AP
U1RNP
Species Homo sapiens
 Database cross references - SNRNP70
ExoCarta ExoCarta_6625
Vesiclepedia VP_6625
Entrez Gene 6625
HGNC 11150
MIM 180740
UniProt P08621  
 SNRNP70 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SNRNP70
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IMP
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
    U1 snRNA binding GO:0030619 IBA
    U1 snRNA binding GO:0030619 IDA
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IBA
    mRNA splicing, via spliceosome GO:0000398 IC
    mRNA splicing, via spliceosome GO:0000398 IDA
    mRNA splicing, via spliceosome GO:0000398 NAS
    regulation of ATP-dependent activity GO:0043462 TAS
    regulation of RNA splicing GO:0043484 IMP
    positive regulation of mRNA splicing, via spliceosome GO:0048026 IEA
    negative regulation of protein refolding GO:0061084 TAS
    negative regulation of chaperone-mediated autophagy GO:1904715 TAS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    spliceosomal complex GO:0005681 IDA
    spliceosomal complex GO:0005681 IPI
    U1 snRNP GO:0005685 IBA
    U1 snRNP GO:0005685 IDA
    U1 snRNP GO:0005685 IPI
    nuclear speck GO:0016607 ISS
    U2-type prespliceosome GO:0071004 IBA
 Experiment description of studies that identified SNRNP70 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SNRNP70
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Co-fractionation Homo sapiens
Affinity Capture-RNA Homo sapiens
2 CDC14B 8555
Affinity Capture-MS Homo sapiens
3 SLFN11 91607
Proximity Label-MS Homo sapiens
4 SRGAP1 57522
Affinity Capture-MS Homo sapiens
5 RIT1 6016
Negative Genetic Homo sapiens
6 CPSF6 11052
Affinity Capture-MS Homo sapiens
7 UBE2H 7328
Affinity Capture-MS Homo sapiens
8 HNRNPC 3183
Co-fractionation Homo sapiens
9 ZC3H14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 NCBP1 4686
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 SNRPG 6637
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 UBL4A 8266
Affinity Capture-MS Homo sapiens
13 SNRPE 6635
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
14 PAXIP1  
Affinity Capture-MS Homo sapiens
15 SLIRP 81892
Co-fractionation Homo sapiens
16 BCLAF1 9774
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
18 SRPK2 6733
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 TGS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 DDX17 10521
Co-purification Homo sapiens
21 ACTC1 70
Proximity Label-MS Homo sapiens
22 LARP1B 55132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 RBMXL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 RPS19 6223
Co-fractionation Homo sapiens
25 KIF20A 10112
Affinity Capture-MS Homo sapiens
26 GEMIN8 54960
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 CSNK2A1 1457
Biochemical Activity Homo sapiens
28 PRPF3  
Co-fractionation Homo sapiens
29 VHL  
Affinity Capture-MS Homo sapiens
30 CAND1 55832
Affinity Capture-MS Homo sapiens
31 HNRNPR 10236
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
32 PRPF40A 55660
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
33 SNRPF 6636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 GCN1L1 10985
Co-fractionation Homo sapiens
35 SNRPD2 6633
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
36 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
37 SF3B2 10992
Co-fractionation Homo sapiens
38 SMN2 6607
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 MRPS18C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 LRP1 4035
Two-hybrid Homo sapiens
41 MRPS35 60488
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 MEPCE 56257
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 PPP1R12A 4659
Co-fractionation Homo sapiens
44 APOBEC3F 200316
Affinity Capture-MS Homo sapiens
45 RNPS1 10921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 CRNKL1 51340
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
47 Elavl1 15568
Affinity Capture-MS Mus musculus
48 KIF23 9493
Affinity Capture-MS Homo sapiens
49 UBE2O 63893
Affinity Capture-MS Homo sapiens
50 CASP3 836
Biochemical Activity Homo sapiens
51 H1FX 8971
Co-fractionation Homo sapiens
52 COPS6 10980
Affinity Capture-MS Homo sapiens
53 CCDC137  
Affinity Capture-MS Homo sapiens
54 SRSF10 10772
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 COPS5 10987
Affinity Capture-MS Homo sapiens
56 FBXW7  
Synthetic Lethality Homo sapiens
57 PRC1 9055
Affinity Capture-MS Homo sapiens
58 EML4 27436
Co-fractionation Homo sapiens
59 MRPS24 64951
Affinity Capture-MS Homo sapiens
60 SRRM2 23524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
61 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 IFIT3 3437
Affinity Capture-MS Homo sapiens
63 OBSL1 23363
Affinity Capture-MS Homo sapiens
64 SF3A2 8175
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
65 UBQLN1 29979
Co-fractionation Homo sapiens
66 MRPS26 64949
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 SRSF3 6428
Co-fractionation Homo sapiens
68 RC3H1 149041
Affinity Capture-MS Homo sapiens
69 ITGA4 3676
Affinity Capture-MS Homo sapiens
70 EED  
Affinity Capture-MS Homo sapiens
71 RASGRF1  
Two-hybrid Homo sapiens
72 VCAM1 7412
Affinity Capture-MS Homo sapiens
73 RANBP2 5903
Co-fractionation Homo sapiens
74 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 PFN2 5217
Affinity Capture-MS Homo sapiens
76 SMAD5 4090
Two-hybrid Homo sapiens
77 CUL1 8454
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
78 BTRC 8945
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
79 ARIH2 10425
Affinity Capture-MS Homo sapiens
80 ARHGAP9 64333
Affinity Capture-MS Homo sapiens
81 MTA2 9219
Co-fractionation Homo sapiens
82 GSK3B 2932
Affinity Capture-MS Homo sapiens
83 RNF11 26994
Two-hybrid Homo sapiens
84 GAR1 54433
Affinity Capture-MS Homo sapiens
85 FOXP1 27086
Affinity Capture-MS Homo sapiens
86 LIN28A  
Affinity Capture-MS Homo sapiens
87 RBMX 27316
Affinity Capture-MS Homo sapiens
88 IL32  
Two-hybrid Homo sapiens
89 AURKA 6790
Affinity Capture-MS Homo sapiens
90 CLK2 1196
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
91 DIS3L  
Affinity Capture-MS Homo sapiens
92 HNRNPA1 3178
Co-fractionation Homo sapiens
93 WBP4  
Reconstituted Complex Homo sapiens
94 DDX39B 7919
Co-fractionation Homo sapiens
95 SCAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 FOXC1  
Affinity Capture-MS Homo sapiens
97 PRPF8 10594
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
98 DDX21 9188
Affinity Capture-MS Homo sapiens
99 MRPL45 84311
Affinity Capture-MS Homo sapiens
100 SRRM1 10250
Co-fractionation Homo sapiens
101 SMARCA5 8467
Co-fractionation Homo sapiens
102 CUL4B 8450
Affinity Capture-MS Homo sapiens
103 PARK2  
Affinity Capture-MS Homo sapiens
104 SF3A1 10291
Co-fractionation Homo sapiens
105 PHAX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 CLK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 SNRPA 6626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
108 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 SMARCA4 6597
Co-fractionation Homo sapiens
110 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
111 SNRNP200 23020
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
112 PTCD3 55037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 PRPF6 24148
Two-hybrid Homo sapiens
114 DDX20 11218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 PABPC1 26986
Affinity Capture-MS Homo sapiens
116 MKRN2 23609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 SNRPD1 6632
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
118 TNPO2 30000
Co-fractionation Homo sapiens
119 YAP1 10413
Affinity Capture-MS Homo sapiens
120 BARD1 580
Affinity Capture-MS Homo sapiens
121 NTRK1 4914
Affinity Capture-MS Homo sapiens
122 RPL31 6160
Co-fractionation Homo sapiens
123 SMAD3 4088
Two-hybrid Homo sapiens
124 U2AF2 11338
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
125 CRP  
Affinity Capture-Western Homo sapiens
126 SYNCRIP 10492
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 SLTM 79811
Affinity Capture-MS Homo sapiens
128 DNAJA1 3301
Co-fractionation Homo sapiens
129 LUC7L2 51631
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
130 SMAD2 4087
Two-hybrid Homo sapiens
131 PLEKHG7  
Affinity Capture-MS Homo sapiens
132 SCAF11  
Affinity Capture-MS Homo sapiens
133 RAB3GAP1 22930
Co-fractionation Homo sapiens
134 TUBA1B 10376
Co-fractionation Homo sapiens
135 SRSF8 10929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 HECTD1 25831
Affinity Capture-MS Homo sapiens
137 GEMIN7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 MAGOH 4116
Affinity Capture-MS Homo sapiens
139 CUL2 8453
Affinity Capture-MS Homo sapiens
140 SNRPD3 6634
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
141 SRPK3  
Affinity Capture-MS Homo sapiens
142 UPF1 5976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 DRAP1 10589
Co-fractionation Homo sapiens
144 BZW1 9689
Co-fractionation Homo sapiens
145 CEBPA  
Protein-peptide Homo sapiens
146 ARHGAP20  
Affinity Capture-MS Homo sapiens
147 SRPK1 6732
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
148 AHCYL1 10768
Co-fractionation Homo sapiens
149 TRA2B 6434
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
150 OGT 8473
Reconstituted Complex Homo sapiens
151 VCP 7415
Co-fractionation Homo sapiens
152 SNRPB2 6629
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 LARP1 23367
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 TXN2 25828
Co-fractionation Homo sapiens
155 ZNF326 284695
Affinity Capture-MS Homo sapiens
156 CCDC59  
Affinity Capture-MS Homo sapiens
157 TRMT10A 93587
Co-fractionation Homo sapiens
158 HNRNPDL 9987
Co-fractionation Homo sapiens
159 SRSF11 9295
Co-fractionation Homo sapiens
160 HSPA5 3309
Co-fractionation Homo sapiens
161 ZBTB2 57621
Affinity Capture-MS Homo sapiens
162 RBM39 9584
Co-fractionation Homo sapiens
163 SRRM4  
Two-hybrid Homo sapiens
164 CTNNBL1 56259
Co-fractionation Homo sapiens
165 AIFM1 9131
Cross-Linking-MS (XL-MS) Homo sapiens
166 METTL14  
Affinity Capture-MS Homo sapiens
167 CEP63  
Two-hybrid Homo sapiens
168 DAP3 7818
Affinity Capture-MS Homo sapiens
169 CHERP 10523
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
170 XPO1 7514
Affinity Capture-MS Homo sapiens
171 USP15 9958
Co-fractionation Homo sapiens
172 RC3H2  
Affinity Capture-MS Homo sapiens
173 ECT2 1894
Affinity Capture-MS Homo sapiens
174 DEPDC1B 55789
Affinity Capture-MS Homo sapiens
175 SIRT7  
Affinity Capture-MS Homo sapiens
176 PINX1  
Affinity Capture-MS Homo sapiens
177 CD2BP2 10421
Affinity Capture-MS Homo sapiens
178 IFI16 3428
Affinity Capture-MS Homo sapiens
179 SRSF1 6426
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Far Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
180 ZFR 51663
Affinity Capture-MS Homo sapiens
181 MRPS14  
Affinity Capture-MS Homo sapiens
182 WDR33 55339
Affinity Capture-MS Homo sapiens
183 EPB41L2 2037
Co-fractionation Homo sapiens
184 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 DES 1674
Co-fractionation Homo sapiens
186 MECP2 4204
Affinity Capture-MS Homo sapiens
187 GTPBP1 9567
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 ARHGEF16 27237
Affinity Capture-MS Homo sapiens
189 FUS 2521
Affinity Capture-MS Homo sapiens
190 METTL3  
Affinity Capture-MS Homo sapiens
191 Inpp5b  
Affinity Capture-MS Mus musculus
192 SUZ12  
Affinity Capture-MS Homo sapiens
193 FN1 2335
Affinity Capture-MS Homo sapiens
194 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
195 STRAP 11171
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 YTHDC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 SMAD1 4086
Two-hybrid Homo sapiens
198 NOP10 55505
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 PRMT5 10419
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
200 GEMIN4 50628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 CCDC9  
Affinity Capture-MS Homo sapiens
202 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
203 DKC1 1736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 PRPF19 27339
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
205 MYC  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
206 KIF11 3832
Co-fractionation Homo sapiens
207 SMAD9  
Two-hybrid Homo sapiens
208 YBX3 8531
Affinity Capture-MS Homo sapiens
209 RPP40 10799
Affinity Capture-MS Homo sapiens
210 PRRC2A 7916
Affinity Capture-MS Homo sapiens
211 TOP1 7150
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
212 POP1 10940
Affinity Capture-MS Homo sapiens
213 SRSF12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 MYCN  
Affinity Capture-MS Homo sapiens
215 MATR3 9782
Co-fractionation Homo sapiens
216 MRPS36 92259
Co-fractionation Homo sapiens
217 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 DDRGK1 65992
Affinity Capture-MS Homo sapiens
219 RNF2  
Affinity Capture-MS Homo sapiens
220 TPR 7175
Co-fractionation Homo sapiens
221 XRCC3  
Affinity Capture-MS Homo sapiens
222 ARGLU1  
Co-fractionation Homo sapiens
223 TFIP11  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
224 PLEKHG3 26030
Affinity Capture-MS Homo sapiens
225 RPL26 6154
Affinity Capture-MS Homo sapiens
226 UPF2 26019
Co-fractionation Homo sapiens
227 TPM4 7171
Co-fractionation Homo sapiens
228 SNRPB 6628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
229 RALY 22913
Affinity Capture-MS Homo sapiens
230 GATAD2A 54815
Co-fractionation Homo sapiens
231 TOE1 114034
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
232 PRKD2 25865
Two-hybrid Homo sapiens
233 RELA 5970
Two-hybrid Homo sapiens
234 NUDT21 11051
Reconstituted Complex Homo sapiens
235 MRPS10 55173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 SNW1 22938
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
237 GEMIN2 8487
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 MKRN1 23608
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 RARA 5914
Affinity Capture-MS Homo sapiens
240 TERF2  
Affinity Capture-MS Homo sapiens
241 SIRT6  
Affinity Capture-MS Homo sapiens
242 SMN1 6606
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
243 SHBG 6462
Two-hybrid Homo sapiens
244 SKIL  
Two-hybrid Homo sapiens
245 ILF3 3609
Co-fractionation Homo sapiens
246 RAB3GAP2 25782
Co-fractionation Homo sapiens
247 ZRANB2 9406
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
248 CDKL3  
Two-hybrid Homo sapiens
249 TP53 7157
Affinity Capture-MS Homo sapiens
250 FOLR1 2348
Affinity Capture-MS Homo sapiens
251 RBM25 58517
Co-fractionation Homo sapiens
252 RNH1 6050
Co-fractionation Homo sapiens
253 KLHL8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
254 MRPL15 29088
Affinity Capture-MS Homo sapiens
255 SSRP1 6749
Affinity Capture-MS Homo sapiens
256 GEMIN6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
257 SRSF9 8683
Co-fractionation Homo sapiens
258 SMARCC1 6599
Co-fractionation Homo sapiens
259 PRRC2C 23215
Affinity Capture-MS Homo sapiens
260 MRPS31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 ZCRB1  
Affinity Capture-MS Homo sapiens
262 CUL5 8065
Affinity Capture-MS Homo sapiens
263 KIAA1429 25962
Affinity Capture-MS Homo sapiens
264 SKP1 6500
Affinity Capture-Western Homo sapiens
265 KNOP1 400506
Affinity Capture-MS Homo sapiens
266 DEK 7913
Co-fractionation Homo sapiens
267 SMURF1 57154
Affinity Capture-MS Homo sapiens
268 THRAP3 9967
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
269 SMAD4  
Two-hybrid Homo sapiens
270 PRMT1 3276
Co-fractionation Homo sapiens
271 C9orf114  
Affinity Capture-MS Homo sapiens
272 HDAC1 3065
Co-fractionation Homo sapiens
273 E2F4  
Affinity Capture-MS Homo sapiens
274 STRBP 55342
Affinity Capture-MS Homo sapiens
275 EIF4A3 9775
Affinity Capture-MS Homo sapiens
276 MTHFD1 4522
Co-fractionation Homo sapiens
277 DOCK8 81704
Affinity Capture-MS Homo sapiens
278 RABL6 55684
Co-fractionation Homo sapiens
279 CWC15  
Co-fractionation Homo sapiens
280 HNRNPM 4670
Co-fractionation Homo sapiens
281 HNRNPK 3190
Co-fractionation Homo sapiens
282 CMTR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 UFL1 23376
Affinity Capture-MS Homo sapiens
284 SNRPN 6638
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 LARP7 51574
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 Srsf1 110809
Affinity Capture-MS Mus musculus
287 CHMP4C 92421
Affinity Capture-MS Homo sapiens
288 SNX2 6643
Cross-Linking-MS (XL-MS) Homo sapiens
289 EZH2  
Affinity Capture-MS Homo sapiens
290 SF3B4 10262
Co-fractionation Homo sapiens
291 CAPRIN1 4076
Co-fractionation Homo sapiens
292 MRPS33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
293 TRIM31  
Affinity Capture-MS Homo sapiens
294 KIF14 9928
Affinity Capture-MS Homo sapiens
295 IL7R  
Protein-RNA Homo sapiens
296 RNU1-1  
Affinity Capture-RNA Homo sapiens
297 SF3A3 10946
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
298 GEMIN5 25929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
299 CUL7 9820
Affinity Capture-MS Homo sapiens
300 MYO6 4646
Affinity Capture-MS Homo sapiens
301 HNRNPU 3192
Co-fractionation Homo sapiens
302 C9orf72  
Affinity Capture-MS Homo sapiens
303 ARHGAP24  
Affinity Capture-MS Homo sapiens
304 SMURF2 64750
Two-hybrid Homo sapiens
305 IFIT1 3434
Affinity Capture-MS Homo sapiens
306 MRPS22 56945
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
307 ARHGAP35 2909
Affinity Capture-MS Homo sapiens
308 SNRPA1 6627
Affinity Capture-MS Homo sapiens
309 GTPBP2 54676
Two-hybrid Homo sapiens
310 SP7  
Proximity Label-MS Homo sapiens
311 LUC7L 55692
Co-fractionation Homo sapiens
312 Smn1 20595
Affinity Capture-MS Mus musculus
313 IFIT2 3433
Affinity Capture-MS Homo sapiens
314 MRPS9 64965
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 CUL4A 8451
Affinity Capture-MS Homo sapiens
316 SMARCC2 6601
Co-fractionation Homo sapiens
317 CDC5L 988
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
318 HNRNPA2B1 3181
Co-fractionation Homo sapiens
319 EIF3L 51386
Co-fractionation Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here