Experiment description of studies that identified TOE1 in sEVs

1 Experiment ID 207 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DKO-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

2 Experiment ID 208 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Dks-8 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 209 MISEV standards ✘ Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DLD-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for TOE1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 UBE2H 7328 Affinity Capture-MS Homo sapiens 2 SLFN11 91607 Proximity Label-MS Homo sapiens 3 ZNF668   Affinity Capture-MS Homo sapiens 4 ABCF3 55324 Two-hybrid Homo sapiens 5 APLP1 333 Two-hybrid Homo sapiens 6 H1FNT   Affinity Capture-MS Homo sapiens 7 SNRPG 6637 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 SNRPE 6635 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 ZNF346   Affinity Capture-MS Homo sapiens 10 HIST1H1D 3007 Affinity Capture-MS Homo sapiens 11 RPS19 6223 Affinity Capture-MS Homo sapiens 12 LSM4 25804 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 13 CAND1 55832 Affinity Capture-MS Homo sapiens 14 SNRPF 6636 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 RPS3 6188 Affinity Capture-MS Homo sapiens 16 Pqbp1   Affinity Capture-MS Mus musculus 17 HIST1H1A 3024 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 SNRNP70 6625 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 RASA2 5922 Affinity Capture-MS Homo sapiens 20 LLPH   Affinity Capture-MS Homo sapiens 21 Snw1   Affinity Capture-MS Mus musculus 22 PIM2   Affinity Capture-MS Homo sapiens 23 WDR83   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 24 AGGF1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 25 ZBTB47   Affinity Capture-MS Homo sapiens 26 SNRPC 6631 Affinity Capture-MS Homo sapiens 27 FGF17   Affinity Capture-MS Homo sapiens 28 RPS9 6203 Affinity Capture-MS Homo sapiens 29 Snrnp70 20637 Affinity Capture-MS Mus musculus 30 SNRPD3 6634 Affinity Capture-MS Homo sapiens 31 U2AF1 7307 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 32 ATG16L1 55054 Affinity Capture-MS Homo sapiens 33 RPS3A 6189 Two-hybrid Homo sapiens 34 PRCC   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 35 MECP2 4204 Affinity Capture-MS Homo sapiens 36 MYCN   Affinity Capture-MS Homo sapiens 37 Klc3   Affinity Capture-MS Mus musculus 38 RPL19 6143 Affinity Capture-MS Homo sapiens 39 RBM8A 9939 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 40 RBM19 9904 Affinity Capture-MS Homo sapiens 41 LIN28A   Affinity Capture-MS Homo sapiens 42 PPP1CA 5499 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 43 RPS10 6204 Affinity Capture-MS Homo sapiens 44 YBX2 51087 Affinity Capture-MS Homo sapiens 45 SRSF6 6431 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 46 SH3GL3   Two-hybrid Homo sapiens 47 HIST1H2AM 8336 Affinity Capture-MS Homo sapiens 48 CD2BP2 10421 Affinity Capture-MS Homo sapiens 49 OGT 8473 Reconstituted Complex Homo sapiens 50 RPL31 6160 Affinity Capture-MS Homo sapiens 51 HIST1H1E 3008 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 RAD18   Affinity Capture-MS Homo sapiens 53 SNRPN 6638 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 FBXL6   Affinity Capture-MS Homo sapiens 55 CCDC22 28952 Affinity Capture-MS Homo sapiens 56 SUMO1 7341 Two-hybrid Homo sapiens 57 MAGEB2 4113 Affinity Capture-MS Homo sapiens 58 SNRPB2 6629 Affinity Capture-MS Homo sapiens 59 SF3B2 10992 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 60 RBM39 9584 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 61 RPS2 6187 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 62 CIAO1 9391 Affinity Capture-MS Homo sapiens 63 SRSF4 6429 Affinity Capture-MS Homo sapiens 64 RNU11 26824 Affinity Capture-MS Homo sapiens 65 ANXA1 301 Protein-peptide Homo sapiens 66 CUL3 8452 Affinity Capture-MS Homo sapiens 67 RPL3 6122 Affinity Capture-MS Homo sapiens 68 EGFR 1956 Negative Genetic Homo sapiens 69 WIBG 84305 Co-fractionation Homo sapiens 70 PRR3   Affinity Capture-MS Homo sapiens 71 IL7R   Protein-RNA Homo sapiens 72 IFIT1 3434 Affinity Capture-MS Homo sapiens 73 RPA3 6119 Proximity Label-MS Homo sapiens 74 SART3 9733 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 75 DDRGK1 65992 Affinity Capture-MS Homo sapiens 76 SF3B3 23450 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 77 H2AFB2   Affinity Capture-MS Homo sapiens 78 Dnaja2   Two-hybrid Rattus norvegicus 79 HIST1H1T 3010 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 RPL26 6154 Affinity Capture-MS Homo sapiens 81 CLCN2   Affinity Capture-MS Homo sapiens 82 RBMS2 5939 Affinity Capture-MS Homo sapiens 83 SNRPB 6628 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 84 RPS16 6217 Affinity Capture-MS Homo sapiens 85 EIF2S1 1965 Co-fractionation Homo sapiens 86 SURF6   Affinity Capture-MS Homo sapiens 87 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 88 PARP1 142 Affinity Capture-MS Homo sapiens 89 WDR77 79084 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 90 CPSF6 11052 Affinity Capture-MS Homo sapiens 91 SNUPN 10073 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 92 WWOX 51741 Affinity Capture-MS Homo sapiens 93 SNRPA 6626 Affinity Capture-MS Homo sapiens 94 UTP23   Affinity Capture-MS Homo sapiens 95 NSDHL 50814 Affinity Capture-MS Homo sapiens 96 HIST1H1B 3009 Affinity Capture-MS Homo sapiens 97 NIFK 84365 Affinity Capture-MS Homo sapiens 98 KRR1 11103 Affinity Capture-MS Homo sapiens 99 LARP7 51574 Affinity Capture-MS Homo sapiens 100 NEIL1   Affinity Capture-MS Homo sapiens 101 IK 3550 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 102 RPL7A 6130 Affinity Capture-MS Homo sapiens 103 RPL23AP32 56969 Affinity Capture-MS Homo sapiens 104 CIT 11113 Affinity Capture-MS Homo sapiens 105 HNRNPF 3185 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 106 PRPF4 9128 Affinity Capture-MS Homo sapiens 107 RPL23A 6147 Affinity Capture-MS Homo sapiens 108 KRAS 3845 Negative Genetic Homo sapiens 109 MYC   Affinity Capture-MS Homo sapiens 110 SNRPA1 6627 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 111 ZNF467   Affinity Capture-MS Homo sapiens 112 IFIT2 3433 Affinity Capture-MS Homo sapiens 113 EP300 2033 Affinity Capture-MS Homo sapiens View the network

Pathways in which TOE1 is involved

No pathways found