Experiment description of studies that identified APLP1 in exosomes

1 Experiment ID 834 MISEV standards ✔ EM EV Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 EV Enriched markers ✔ CANX EV Negative markers ✔ NTA EV Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM EV Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 EV Enriched markers ✔ CANX EV Negative markers ✔ NTA EV Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for APLP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HSPE1 3336 Two-hybrid Homo sapiens 2 SAT   Two-hybrid Homo sapiens 3 TCF21   Two-hybrid Homo sapiens 4 MPHOSPH6 10200 Two-hybrid Homo sapiens 5 TOE1 114034 Two-hybrid Homo sapiens 6 DAB2 1601 Reconstituted Complex Homo sapiens 7 TK1 7083 Two-hybrid Homo sapiens 8 GSTM4 2948 Two-hybrid Homo sapiens 9 NACA 4666 Two-hybrid Homo sapiens 10 PHF10   Two-hybrid Homo sapiens 11 UTP14A 10813 Two-hybrid Homo sapiens 12 DAB1 1600 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 13 APBB1   Affinity Capture-MS Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens 14 EIF2S2 8894 Two-hybrid Homo sapiens 15 C1orf42   Two-hybrid Homo sapiens 16 HLA-DQA1 3117 Two-hybrid Homo sapiens 17 ZNF24   Two-hybrid Homo sapiens 18 TSC22D1 8848 Two-hybrid Homo sapiens 19 Tmsb4x   Two-hybrid Mus musculus 20 PCDHA4 56144 Two-hybrid Homo sapiens 21 PNP 4860 Two-hybrid Homo sapiens 22 STX5 6811 Two-hybrid Homo sapiens 23 CDKN2C   Two-hybrid Homo sapiens View the network

Pathways in which APLP1 is involved

No pathways found