Experiment description of studies that identified APLP1 in exosomes

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for APLP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HAP1   Two-hybrid Homo sapiens 2 HSPE1 3336 Two-hybrid Homo sapiens 3 SNCA 6622 Two-hybrid Homo sapiens 4 TCF21   Two-hybrid Homo sapiens 5 MPHOSPH6 10200 Two-hybrid Homo sapiens 6 TOE1 114034 Two-hybrid Homo sapiens 7 DAB2 1601 Reconstituted Complex Homo sapiens 8 TK1 7083 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 9 PRNP 5621 Two-hybrid Homo sapiens 10 ING5   Two-hybrid Homo sapiens 11 ANXA7 310 Two-hybrid Homo sapiens 12 GSTM4 2948 Two-hybrid Homo sapiens 13 PIN1 5300 Two-hybrid Homo sapiens 14 NACA 4666 Two-hybrid Homo sapiens 15 PHF10   Two-hybrid Homo sapiens 16 GLP1R   PCA Homo sapiens Affinity Capture-Western Homo sapiens 17 UTP14A 10813 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 18 DAB1 1600 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 19 CDKN1A   Two-hybrid Homo sapiens 20 APBB3   Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 APBB1   Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 KAT5   Two-hybrid Homo sapiens 23 EIF2S2 8894 Two-hybrid Homo sapiens 24 RBM48   Two-hybrid Homo sapiens 25 SETDB1   Two-hybrid Homo sapiens 26 LRIF1   Two-hybrid Homo sapiens 27 CSNK2B 1460 Two-hybrid Homo sapiens 28 HLA-DQA1 3117 Two-hybrid Homo sapiens 29 ZNF24   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 30 TSC22D1 8848 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 31 Tmsb4x   Two-hybrid Mus musculus 32 CDK4 1019 Two-hybrid Homo sapiens 33 ARRB1 408 Affinity Capture-MS Homo sapiens 34 APBB2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 RAP1B 5908 Two-hybrid Homo sapiens 36 Apbb1   Two-hybrid Mus musculus 37 PCDHA4 56144 Two-hybrid Homo sapiens 38 SMN1 6606 Two-hybrid Homo sapiens 39 PNP 4860 Two-hybrid Homo sapiens 40 STX5 6811 Two-hybrid Homo sapiens 41 VIM 7431 Two-hybrid Homo sapiens 42 SAT1   Two-hybrid Homo sapiens 43 GDF9 2661 Two-hybrid Homo sapiens 44 CDKN2C   Two-hybrid Homo sapiens 45 CRCT1   Two-hybrid Homo sapiens 46 RCC1 1104 Two-hybrid Homo sapiens 47 EEF1A1 1915 Two-hybrid Homo sapiens View the network

Pathways in which APLP1 is involved

No pathways found