Gene description for UTP14A
Gene name UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
Gene symbol UTP14A
Other names/aliases NYCO16
SDCCAG16
dJ537K23.3
Species Homo sapiens
 Database cross references - UTP14A
ExoCarta ExoCarta_10813
Entrez Gene 10813
HGNC 10665
MIM 300508
UniProt Q9BVJ6  
 UTP14A identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
 Gene ontology annotations for UTP14A
Molecular Function
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    rRNA processing GO:0006364 IEA
Subcellular Localization
    nucleolus GO:0005730 IBA
    small-subunit processome GO:0032040 IBA
 Experiment description of studies that identified UTP14A in exosomes
1
Experiment ID 207
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 208
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 209
ISEV standards
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
FLOT1
EV Membrane markers
VDAC
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UTP14A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DLEU1  
Two-hybrid Homo sapiens
2 TRDMT1  
Two-hybrid Homo sapiens
3 ARIH2  
Two-hybrid Homo sapiens
4 TP53BP2  
Two-hybrid Homo sapiens
5 ZNF24  
Two-hybrid Homo sapiens
6 PSG1  
Two-hybrid Homo sapiens
7 RHOH  
Two-hybrid Homo sapiens
8 MGR2  
Two-hybrid Homo sapiens
9 RPA2 6118
Two-hybrid Homo sapiens
10 PHF10  
Two-hybrid Homo sapiens
11 WDR33 55339
Two-hybrid Homo sapiens
12 ABCB7  
Two-hybrid Homo sapiens
13 CPE  
Two-hybrid Homo sapiens
14 RGS1  
Two-hybrid Homo sapiens
15 CCDC106  
Two-hybrid Homo sapiens
16 HOOK2  
Two-hybrid Homo sapiens
17 AXIN1  
Two-hybrid Homo sapiens
18 APLP1  
Two-hybrid Homo sapiens
19 TERF1 7013
Two-hybrid Homo sapiens
20 RNF10  
Two-hybrid Homo sapiens
21 PTPRS 5802
Two-hybrid Homo sapiens
22 LSM3 27258
Two-hybrid Homo sapiens
23 PDCD5 9141
Two-hybrid Homo sapiens
24 PTEN  
Two-hybrid Homo sapiens
25 LAMTOR5  
Two-hybrid Homo sapiens
26 DIPA  
Two-hybrid Homo sapiens
27 LDOC1  
Two-hybrid Homo sapiens
28 PDZK1IP1 10158
Two-hybrid Homo sapiens
29 KIAA0980  
Two-hybrid Homo sapiens
30 SSR1 6745
Two-hybrid Homo sapiens
31 RABIF  
Two-hybrid Homo sapiens
32 TINAGL1 64129
Two-hybrid Homo sapiens
33 RSRC1  
Two-hybrid Homo sapiens
34 Cep70  
Two-hybrid Homo sapiens
35 HNRNPH3 3189
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which UTP14A is involved
No pathways found





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