Gene description for HIST1H1T
Gene name histone cluster 1, H1t
Gene symbol HIST1H1T
Other names/aliases H1.6
H1FT
H1t
dJ221C16.2
Species Homo sapiens
 Database cross references - HIST1H1T
ExoCarta ExoCarta_3010
Entrez Gene 3010
HGNC 4720
MIM 142712
UniProt P22492  
 HIST1H1T identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for HIST1H1T
Molecular Function
    DNA binding GO:0003677 IEA
Biological Process
    sperm motility GO:0030317 IEA
    spermatogenesis GO:0007283 IEA
    cell differentiation GO:0030154 IEA
    binding of sperm to zona pellucida GO:0007339 IEA
    nucleosome assembly GO:0006334 IEA
    multicellular organismal development GO:0007275 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    condensed nuclear chromosome GO:0000794 IEA
    nucleosome GO:0000786 IEA
 Experiment description of studies that identified HIST1H1T in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for HIST1H1T
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HIST1H1T is involved
No pathways found





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