Gene description for NOC4L
Gene name nucleolar complex associated 4 homolog (S. cerevisiae)
Gene symbol NOC4L
Other names/aliases NET49
NOC4
UTP19
Species Homo sapiens
 Database cross references - NOC4L
ExoCarta ExoCarta_79050
Vesiclepedia VP_79050
Entrez Gene 79050
HGNC 28461
MIM 612819
UniProt Q9BVI4  
 NOC4L identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for NOC4L
Molecular Function
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    rRNA processing GO:0006364 ISS
Subcellular Localization
    Noc4p-Nop14p complex GO:0030692 IBA
    integral component of membrane GO:0016021 IEA
    nuclear membrane GO:0031965 IEA
    nucleolus GO:0005730 ISS
    small-subunit processome GO:0032040 IBA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified NOC4L in exosomes
1
Experiment ID 488
ISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NOC4L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 USHBP1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
2 NT5C2 22978
Two-hybrid Homo sapiens
3 DAZAP2  
Two-hybrid Homo sapiens
4 EFCBP2  
Two-hybrid Homo sapiens
5 TSC22D4 81628
Two-hybrid Homo sapiens
6 VIM 7431
Two-hybrid Homo sapiens
7 PLSCR1 5359
Two-hybrid Homo sapiens
8 PRSS23 11098
Two-hybrid Homo sapiens
9 KRT15 3866
Two-hybrid Homo sapiens
10 SSSCA1 10534
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which NOC4L is involved
No pathways found





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