Gene description for CEP250
Gene name centrosomal protein 250kDa
Gene symbol CEP250
Other names/aliases C-NAP1
CEP2
CNAP1
Species Homo sapiens
 Database cross references - CEP250
ExoCarta ExoCarta_11190
Entrez Gene 11190
HGNC 1859
MIM 609689
UniProt Q9BV73  
 CEP250 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CEP250
Molecular Function
    protein kinase binding GO:0019901 IPI
    protein binding GO:0005515 IPI
    protein C-terminus binding GO:0008022 IPI
    protein domain specific binding GO:0019904 IPI
Biological Process
    mitotic cell cycle GO:0000278 TAS
    protein localization GO:0008104 IMP
    nonmotile primary cilium assembly GO:0035058 IMP
    centriole-centriole cohesion GO:0010457 IMP
    protein localization to organelle GO:0033365 IMP
    organelle organization GO:0006996 TAS
    regulation of centriole-centriole cohesion GO:0030997 IDA
    G2/M transition of mitotic cell cycle GO:0000086 TAS
Subcellular Localization
    cytosol GO:0005829 TAS
    protein complex GO:0043234 IMP
    perinuclear region of cytoplasm GO:0048471 IEA
    centriole GO:0005814 IDA
    microtubule organizing center GO:0005815 NAS
    spindle pole centrosome GO:0031616 IEA
    centrosome GO:0005813 IDA
    cilium GO:0005929 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified CEP250 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CEP250
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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