Gene description for MAP7D3
Gene name MAP7 domain containing 3
Gene symbol MAP7D3
Other names/aliases MDP3
Species Homo sapiens
 Database cross references - MAP7D3
ExoCarta ExoCarta_79649
Entrez Gene 79649
HGNC 25742
MIM 300930
UniProt Q8IWC1  
 MAP7D3 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for MAP7D3
Molecular Function
    structural molecule activity GO:0005198 IBA
    microtubule binding GO:0008017 IDA
    tubulin binding GO:0015631 IDA
Biological Process
    microtubule polymerization GO:0046785 IDA
    microtubule cytoskeleton organization GO:0000226 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    actin cytoskeleton GO:0015629 IDA
    cytoplasm GO:0005737 IDA
    microtubule cytoskeleton GO:0015630 IBA
    centrosome GO:0005813 IDA
    spindle GO:0005819 IEA
    membrane GO:0016020 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified MAP7D3 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
2
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for MAP7D3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MAP7D3 is involved
No pathways found





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