Gene description for ZC3HAV1
Gene name zinc finger CCCH-type, antiviral 1
Gene symbol ZC3HAV1
Other names/aliases ARTD13
FLB6421
PARP13
ZAP
ZC3H2
ZC3HDC2
Species Homo sapiens
 Database cross references - ZC3HAV1
ExoCarta ExoCarta_56829
Vesiclepedia VP_56829
Entrez Gene 56829
HGNC 23721
MIM 607312
UniProt Q7Z2W4  
 ZC3HAV1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for ZC3HAV1
Molecular Function
    RNA binding GO:0003723 HDA
    NAD+-protein poly-ADP-ribosyltransferase activity GO:0003950 IMP
    protein binding GO:0005515 IPI
    cadherin binding GO:0045296 HDA
    metal ion binding GO:0046872 IEA
    NAD+ binding GO:0070403 IMP
    NAD+-protein ADP-ribosyltransferase activity GO:1990404 IDA
Biological Process
    response to virus GO:0009615 IBA
    response to virus GO:0009615 IDA
    positive regulation of type I interferon production GO:0032481 IBA
    positive regulation of interferon-alpha production GO:0032727 IDA
    positive regulation of interferon-beta production GO:0032728 IDA
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 IMP
    negative regulation of viral genome replication GO:0045071 IDA
    innate immune response GO:0045087 IEA
    defense response to virus GO:0051607 IEA
    positive regulation of mRNA catabolic process GO:0061014 IBA
    positive regulation of mRNA catabolic process GO:0061014 IDA
    protein poly-ADP-ribosylation GO:0070212 IMP
    positive regulation of RIG-I signaling pathway GO:1900246 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IDA
    lysosome GO:0005764 IEA
    late endosome GO:0005770 IEA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified ZC3HAV1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
13
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
19
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
24
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
26
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
29
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
45
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
46
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZC3HAV1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GJD3  
Proximity Label-MS Homo sapiens
2 ISG15 9636
Affinity Capture-MS Homo sapiens
3 ZNF346  
Affinity Capture-MS Homo sapiens
4 ATG9A 79065
Proximity Label-MS Homo sapiens
5 RTCA 8634
Co-fractionation Homo sapiens
6 BRCA1 672
Affinity Capture-MS Homo sapiens
7 NMNAT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 KIF20A 10112
Affinity Capture-MS Homo sapiens
9 UTP3 57050
Affinity Capture-MS Homo sapiens
10 PCBP3 54039
Two-hybrid Homo sapiens
11 APEX1 328
Affinity Capture-RNA Homo sapiens
12 GPATCH4 54865
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 WDR76  
Affinity Capture-MS Homo sapiens
14 WHSC1 7468
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 KIF23 9493
Affinity Capture-MS Homo sapiens
16 FBL 2091
Proximity Label-MS Homo sapiens
17 PTCD1 26024
Affinity Capture-MS Homo sapiens
18 SLC25A46 91137
Proximity Label-MS Homo sapiens
19 FAM120A 23196
Affinity Capture-MS Homo sapiens
20 KIF14 9928
Affinity Capture-MS Homo sapiens
21 MTCH2 23788
Proximity Label-MS Homo sapiens
22 LIN28B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 SRSF3 6428
Affinity Capture-MS Homo sapiens
24 YBX2 51087
Affinity Capture-MS Homo sapiens
25 LDHD  
Affinity Capture-MS Homo sapiens
26 MCAM 4162
Proximity Label-MS Homo sapiens
27 PURG  
Affinity Capture-MS Homo sapiens
28 MIRLET7A1  
Affinity Capture-RNA Homo sapiens
29 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
30 RPL18A 6142
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 CDH1 999
Proximity Label-MS Homo sapiens
32 OGT 8473
Reconstituted Complex Homo sapiens
33 RPL31 6160
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 KHNYN 23351
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 CBX6  
Affinity Capture-MS Homo sapiens
36 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 HECTD1 25831
Affinity Capture-MS Homo sapiens
38 SRPK3  
Affinity Capture-MS Homo sapiens
39 MAGEB2 4113
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 GTPBP4 23560
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 CCNT1  
Affinity Capture-MS Homo sapiens
42 REEP5 7905
Proximity Label-MS Homo sapiens
43 ANLN 54443
Affinity Capture-MS Homo sapiens
44 PHLPP1  
Proximity Label-MS Homo sapiens
45 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
46 ABT1 29777
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 LRRC59 55379
Proximity Label-MS Homo sapiens
48 SIRT7  
Affinity Capture-MS Homo sapiens
49 SRSF4 6429
Affinity Capture-MS Homo sapiens
50 NPM3 10360
Affinity Capture-MS Homo sapiens
51 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 FKBP8 23770
Proximity Label-MS Homo sapiens
54 PAPD5 64282
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 GADD45GIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 SLTM 79811
Co-fractionation Homo sapiens
57 NIP7 51388
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 NTHL1  
Co-fractionation Homo sapiens
59 ZNF512  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 MRPL24  
Affinity Capture-MS Homo sapiens
61 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
62 RPA3 6119
Proximity Label-MS Homo sapiens
63 HSP90AA2P 3324
Affinity Capture-MS Homo sapiens
64 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 PVR 5817
Co-fractionation Homo sapiens
66 ILK 3611
Affinity Capture-MS Homo sapiens
67 Rpl35 66489
Affinity Capture-MS Mus musculus
68 AKT1 207
Biochemical Activity Homo sapiens
69 YBX1 4904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 COPZ1 22818
Affinity Capture-MS Homo sapiens
71 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 APOBEC3D  
Affinity Capture-MS Homo sapiens
73 MRPS18C  
Affinity Capture-MS Homo sapiens
74 H2AFB3  
Affinity Capture-MS Homo sapiens
75 KRR1 11103
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 LARP7 51574
Affinity Capture-MS Homo sapiens
77 NEIL1  
Affinity Capture-MS Homo sapiens
78 RPS24 6229
Affinity Capture-MS Homo sapiens
79 NCL 4691
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
80 SORT1 6272
Affinity Capture-MS Homo sapiens
81 RPL23AP32 56969
Affinity Capture-MS Homo sapiens
82 RAB11A 8766
Proximity Label-MS Homo sapiens
83 GLTSCR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 EPHA2 1969
Proximity Label-MS Homo sapiens
85 RPL23A 6147
Affinity Capture-MS Homo sapiens
86 RAB5C 5878
Proximity Label-MS Homo sapiens
87 Hspa5 14828
Two-hybrid Mus musculus
88 DERL1 79139
Proximity Label-MS Homo sapiens
89 IFT74 80173
Affinity Capture-MS Homo sapiens
90 SNRPA 6626
Two-hybrid Homo sapiens
91 H1FNT  
Affinity Capture-MS Homo sapiens
92 SPRTN  
Affinity Capture-MS Homo sapiens
93 ATG5 9474
Proximity Label-MS Homo sapiens
94 LAMP3  
Proximity Label-MS Homo sapiens
95 KIAA0020 9933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 GJA1 2697
Proximity Label-MS Homo sapiens
97 TARDBP 23435
Affinity Capture-MS Homo sapiens
98 BTF3 689
Affinity Capture-MS Homo sapiens
99 HNRNPD 3184
Affinity Capture-MS Homo sapiens
100 RPL14 9045
Affinity Capture-MS Homo sapiens
101 CAND1 55832
Affinity Capture-MS Homo sapiens
102 RSBN1  
Affinity Capture-MS Homo sapiens
103 RBM34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 FIS1 51024
Proximity Label-MS Homo sapiens
106 B3GNT2 10678
Affinity Capture-MS Homo sapiens
107 DDX24 57062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 PRC1 9055
Affinity Capture-MS Homo sapiens
109 NPM1 4869
Affinity Capture-MS Homo sapiens
110 KRI1  
Affinity Capture-MS Homo sapiens
111 PAK1IP1  
Affinity Capture-MS Homo sapiens
112 KLF4  
Affinity Capture-MS Homo sapiens
113 OASL 8638
Affinity Capture-MS Homo sapiens
114 EBAG9 9166
Proximity Label-MS Homo sapiens
115 PES1 23481
Affinity Capture-MS Homo sapiens
116 ZCRB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 MRPS35 60488
Affinity Capture-MS Homo sapiens
118 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
119 DDX21 9188
Affinity Capture-MS Homo sapiens
120 THAP3  
Affinity Capture-MS Homo sapiens
121 RPL4 6124
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 RBM28 55131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 DRG1 4733
Affinity Capture-MS Homo sapiens
124 LYN 4067
Proximity Label-MS Homo sapiens
125 ZBTB48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 Pabpc1 18458
Affinity Capture-MS Mus musculus
127 DDX10  
Affinity Capture-MS Homo sapiens
128 LYAR 55646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 RPLP0 6175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 DDX27 55661
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 C7orf50 84310
Affinity Capture-MS Homo sapiens
132 RSL1D1 26156
Affinity Capture-MS Homo sapiens
133 FGFBP1 9982
Affinity Capture-MS Homo sapiens
134 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
135 RPL32 6161
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 RPN2 6185
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 RAB7A 7879
Proximity Label-MS Homo sapiens
138 RPS2 6187
Affinity Capture-MS Homo sapiens
139 XPO1 7514
Affinity Capture-MS Homo sapiens
140 RC3H2  
Affinity Capture-MS Homo sapiens
141 SRSF5 6430
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 EGFR 1956
Affinity Capture-MS Homo sapiens
143 CEP250 11190
Affinity Capture-MS Homo sapiens
144 MYC  
Affinity Capture-MS Homo sapiens
145 ATP2A1 487
Proximity Label-MS Homo sapiens
146 NOL12 79159
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 GZF1  
Affinity Capture-MS Homo sapiens
148 SAP25  
Affinity Capture-MS Homo sapiens
149 DDRGK1 65992
Affinity Capture-MS Homo sapiens
150 RHOB 388
Proximity Label-MS Homo sapiens
151 NOP16 51491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 H2AFB2  
Affinity Capture-MS Homo sapiens
153 CCDC140  
Affinity Capture-MS Homo sapiens
154 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 RPL26 6154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 FTSJ3 117246
Affinity Capture-MS Homo sapiens
157 RAE1 8480
Co-fractionation Homo sapiens
158 OST4  
Affinity Capture-MS Homo sapiens
159 RPL19 6143
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 RNF43  
Proximity Label-MS Homo sapiens
162 SURF6  
Affinity Capture-MS Homo sapiens
163 RNF151  
Affinity Capture-MS Homo sapiens
164 ILF3 3609
Affinity Capture-MS Homo sapiens
165 TP53 7157
Affinity Capture-MS Homo sapiens
166 KNOP1 400506
Affinity Capture-MS Homo sapiens
167 UTP23  
Affinity Capture-MS Homo sapiens
168 NIFK 84365
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 YBX3 8531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 RPL7A 6130
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 GLYR1 84656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 KRAS 3845
Proximity Label-MS Homo sapiens
173 CKAP4 10970
Proximity Label-MS Homo sapiens
174 PRMT1 3276
Affinity Capture-MS Homo sapiens
175 ZNF467  
Affinity Capture-MS Homo sapiens
176 MRPS9 64965
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 ZNF668  
Affinity Capture-MS Homo sapiens
178 RPSA 3921
Affinity Capture-MS Homo sapiens
179 RPL26L1 51121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 OCLN 100506658
Proximity Label-MS Homo sapiens
181 MARCKS 4082
Proximity Label-MS Homo sapiens
182 USP48  
Co-fractionation Homo sapiens
183 RPS19 6223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 MDFI  
Two-hybrid Homo sapiens
185 SSB 6741
Affinity Capture-MS Homo sapiens
186 PTPN1 5770
Proximity Label-MS Homo sapiens
187 STX4 6810
Proximity Label-MS Homo sapiens
188 RPL10A 4736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 LLPH  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
190 CCDC137  
Affinity Capture-MS Homo sapiens
191 IMP3 55272
Affinity Capture-MS Homo sapiens
192 EIF3B 8662
Cross-Linking-MS (XL-MS) Homo sapiens
193 RAB3B 5865
Proximity Label-MS Homo sapiens
194 ZBTB47  
Affinity Capture-MS Homo sapiens
195 ANOS1 3730
Affinity Capture-MS Homo sapiens
196 SSR1 6745
Proximity Label-MS Homo sapiens
197 ZNF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 SRP14 6727
Affinity Capture-MS Homo sapiens
199 RBM4B  
Affinity Capture-MS Homo sapiens
200 BMI1  
Affinity Capture-MS Homo sapiens
201 DDX18 8886
Affinity Capture-MS Homo sapiens
202 ATG16L1 55054
Affinity Capture-MS Homo sapiens
203 MAVS 57506
Proximity Label-MS Homo sapiens
204 Klc3  
Affinity Capture-MS Mus musculus
205 MTERF3  
Affinity Capture-MS Homo sapiens
206 METTL7A 25840
Proximity Label-MS Homo sapiens
207 RBM19 9904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 FOXP1 27086
Protein-RNA Homo sapiens
209 LIN28A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 NUP155 9631
Proximity Label-MS Homo sapiens
211 BRIX1 55299
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
212 PXMP2  
Proximity Label-MS Homo sapiens
213 DLD 1738
Affinity Capture-MS Homo sapiens
214 FOXA1  
Affinity Capture-MS Homo sapiens
215 PARK2  
Affinity Capture-MS Homo sapiens
216 CXADR 1525
Proximity Label-MS Homo sapiens
217 RPS10 6204
Affinity Capture-MS Homo sapiens
218 MEX3C 51320
Affinity Capture-MS Homo sapiens
219 RAB4A 5867
Proximity Label-MS Homo sapiens
220 NOP2 4839
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 CHMP4B 128866
Affinity Capture-MS Homo sapiens
222 RPA2 6118
Proximity Label-MS Homo sapiens
223 NTRK1 4914
Affinity Capture-MS Homo sapiens
224 ZNF354A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 RPL36 25873
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 RPA4  
Proximity Label-MS Homo sapiens
227 RPN1 6184
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 DHX9 1660
Affinity Capture-MS Homo sapiens
229 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
230 MRPL2 51069
Affinity Capture-MS Homo sapiens
231 RMDN3 55177
Proximity Label-MS Homo sapiens
232 RPL11 6135
Affinity Capture-MS Homo sapiens
233 LARP1 23367
Affinity Capture-MS Homo sapiens
234 WDR46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 BAZ1B 9031
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 ECT2 1894
Affinity Capture-MS Homo sapiens
237 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
238 HSD3B7 80270
Proximity Label-MS Homo sapiens
239 STIM1 6786
Proximity Label-MS Homo sapiens
240 RPL21 6144
Affinity Capture-MS Homo sapiens
241 DHX30 22907
Affinity Capture-MS Homo sapiens
242 ACE2 59272
Affinity Capture-MS Homo sapiens
243 PDCD11 22984
Affinity Capture-MS Homo sapiens
244 Pcbp1 23983
Two-hybrid Mus musculus
245 OCIAD1 54940
Proximity Label-MS Homo sapiens
246 ZNF777  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
247 PRR3  
Affinity Capture-MS Homo sapiens
248 RPS13 6207
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 RAB9A 9367
Proximity Label-MS Homo sapiens
250 RPL12 6136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 HP1BP3 50809
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 RPL18 6141
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
253 RNF2  
Affinity Capture-MS Homo sapiens
254 AKAP1 8165
Proximity Label-MS Homo sapiens
255 RBMS2 5939
Affinity Capture-MS Homo sapiens
256 ZNF574  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
257 AHSA1 10598
Affinity Capture-MS Homo sapiens
258 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
259 HMGN4  
Affinity Capture-MS Homo sapiens
260 FBXL6  
Affinity Capture-MS Homo sapiens
261 PRDM15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 PDHA1 5160
Affinity Capture-MS Homo sapiens
263 C11orf52 91894
Proximity Label-MS Homo sapiens
264 TRIM25 7706
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
265 UFL1 23376
Affinity Capture-MS Homo sapiens
266 SEC61B 10952
Proximity Label-MS Homo sapiens
267 IL17B 27190
Affinity Capture-MS Homo sapiens
268 GLI4  
Affinity Capture-MS Homo sapiens
269 RPL8 6132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 RPL28 6158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
271 SERBP1 26135
Proximity Label-MS Homo sapiens
272 STT3B 201595
Affinity Capture-MS Homo sapiens
273 RPL36AL 6166
Affinity Capture-MS Homo sapiens
274 RC3H1 149041
Affinity Capture-MS Homo sapiens
275 CAV1 857
Proximity Label-MS Homo sapiens
276 GNL2 29889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
277 UBE2H 7328
Affinity Capture-MS Homo sapiens
278 INSIG1  
Affinity Capture-MS Homo sapiens
279 HSD17B11 51170
Proximity Label-MS Homo sapiens
280 CNBP 7555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
281 RPS3A 6189
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
282 RPL30 6156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 PABPC4L 132430
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 RPL13A 23521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 RPL37A 6168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 TRUB2  
Affinity Capture-MS Homo sapiens
288 NGRN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 RPL15 6138
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 LAMP2 3920
Proximity Label-MS Homo sapiens
291 DNAJC25 548645
Proximity Label-MS Homo sapiens
292 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
293 USP36  
Affinity Capture-MS Homo sapiens
294 MRPS5 64969
Affinity Capture-MS Homo sapiens
295 RPS20 6224
Proximity Label-MS Homo sapiens
296 B3GAT1  
Proximity Label-MS Homo sapiens
297 KRTAP10-6  
Two-hybrid Homo sapiens
298 DCTN4 51164
Proximity Label-MS Homo sapiens
299 COPS5 10987
Affinity Capture-MS Homo sapiens
300 MRPS24 64951
Affinity Capture-MS Homo sapiens
301 Hnrnpk 15387
Two-hybrid Mus musculus
302 DDOST 1650
Affinity Capture-MS Homo sapiens
303 MRPS26 64949
Affinity Capture-MS Homo sapiens
304 ADARB1 104
Affinity Capture-MS Homo sapiens
305 STAU2 27067
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 PRKRA 8575
Affinity Capture-MS Homo sapiens
307 EXD2  
Proximity Label-MS Homo sapiens
308 STX6 10228
Proximity Label-MS Homo sapiens
309 RRP8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
310 RAB35 11021
Proximity Label-MS Homo sapiens
311 MYCN  
Affinity Capture-MS Homo sapiens
312 MAK16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 FAM20C 56975
Affinity Capture-MS Homo sapiens
314 CTCF  
Affinity Capture-MS Homo sapiens
315 LAMTOR1 55004
Proximity Label-MS Homo sapiens
316 CPEB1  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
317 E2F4  
Affinity Capture-MS Homo sapiens
318 COX15 1355
Affinity Capture-MS Homo sapiens
319 EMD 2010
Proximity Label-MS Homo sapiens
320 STAU1 6780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
321 APOBEC3C 27350
Affinity Capture-MS Homo sapiens
322 SRSF6 6431
Affinity Capture-MS Homo sapiens
323 IFI16 3428
Affinity Capture-MS Homo sapiens
324 RHOT2 89941
Proximity Label-MS Homo sapiens
325 ELOVL5 60481
Proximity Label-MS Homo sapiens
326 DAXX  
Affinity Capture-MS Homo sapiens
327 RPF1  
Affinity Capture-MS Homo sapiens
328 SRSF11 9295
Two-hybrid Homo sapiens
329 SFPQ 6421
Co-fractionation Homo sapiens
330 PANX1 24145
Proximity Label-MS Homo sapiens
331 DNAJC2 27000
Affinity Capture-MS Homo sapiens
332 RPL35 11224
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
333 LAMP1 3916
Proximity Label-MS Homo sapiens
334 SRSF1 6426
Affinity Capture-MS Homo sapiens
335 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
336 RPL3 6122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
337 ARF6 382
Proximity Label-MS Homo sapiens
338 RPL7 6129
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
339 ZC3H10  
Affinity Capture-MS Homo sapiens
340 NXF1 10482
Two-hybrid Homo sapiens
341 NXF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 AURKB 9212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
343 DKC1 1736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
344 ZC3H3  
Affinity Capture-MS Homo sapiens
345 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
346 ESR2  
Affinity Capture-MS Homo sapiens
347 ANKFY1 51479
Proximity Label-MS Homo sapiens
348 SIRT6  
Affinity Capture-MS Homo sapiens
349 MAST3  
Affinity Capture-MS Homo sapiens
350 MNDA 4332
Affinity Capture-MS Homo sapiens
351 MRPS31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
352 DGCR8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
353 RPS15 6209
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
355 NSA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
356 HDGF 3068
Affinity Capture-MS Homo sapiens
357 RAB5A 5868
Proximity Label-MS Homo sapiens
358 MOV10 4343
Affinity Capture-MS Homo sapiens
359 EZH2  
Affinity Capture-MS Homo sapiens
360 SEC62 7095
Proximity Label-MS Homo sapiens
361 TRIP4 9325
Affinity Capture-MS Homo sapiens
362 UPF1 5976
Affinity Capture-MS Homo sapiens
363 CBX8 57332
Affinity Capture-MS Homo sapiens
364 RPS6 6194
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
365 DNAJC1 64215
Affinity Capture-MS Homo sapiens
366 IVNS1ABP  
Affinity Capture-MS Homo sapiens
367 RPL17 6139
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here