Gene description for Hspa5
Gene name	heat shock protein 5
Gene symbol	Hspa5
Other names/aliases	AL022860 AU019543 Bip D2Wsu141e D2Wsu17e Grp78 Hsce70 SEZ-7 Sez7 baffled mBiP
Species	Mus musculus
Database cross references - Hspa5
ExoCarta	ExoCarta_14828
Entrez Gene	14828
UniProt	P20029
Hspa5 identified in exosomes derived from the following tissue/cell type
Fibroblasts	23260141
Mast cells	17486113
Oligodendrocytes	21136642
Pancreatic cells	19351151

Gene ontology annotations for Hspa5

Molecular Function     enzyme binding GO:0019899 ISO     misfolded protein binding GO:0051787 ISO     ubiquitin protein ligase binding GO:0031625 ISO     ATP binding GO:0005524 IEA     glycoprotein binding GO:0001948 ISO     unfolded protein binding GO:0051082 ISO     ribosome binding GO:0043022 IDA     protein binding GO:0005515 IPI     nucleotide binding GO:0000166 IEA     ATPase activity GO:0016887 ISO     protein domain specific binding GO:0019904 ISO Biological Process     maintenance of protein localization in endoplasmic reticulum GO:0035437 ISO     proteolysis involved in cellular protein catabolic process GO:0051603 IDA     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IGI     cerebellar Purkinje cell layer development GO:0021680 IMP     toxin transport GO:1901998 IMP     positive regulation of protein ubiquitination GO:0031398 IMP     positive regulation of embryonic development GO:0040019 TAS     positive regulation of cell migration GO:0030335 ISO     cellular response to glucose starvation GO:0042149 ISO     cerebellum structural organization GO:0021589 IMP     response to endoplasmic reticulum stress GO:0034976 ISO     activation of signaling protein activity involved in unfolded protein response GO:0006987 IMP     cellular response to interleukin-4 GO:0071353 IDA     negative regulation of apoptotic process GO:0043066 ISO     ER overload response GO:0006983 IDA Subcellular Localization     focal adhesion GO:0005925 ISO     cell surface GO:0009986 IDA     plasma membrane GO:0005886 IDA     nucleus GO:0005634 ISO     smooth endoplasmic reticulum GO:0005790 ISO     cytoplasm GO:0005737 IEA     endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO     endoplasmic reticulum chaperone complex GO:0034663 ISO     midbody GO:0030496 ISO     mitochondrion GO:0005739 ISO     endoplasmic reticulum lumen GO:0005788 IDA     endoplasmic reticulum GO:0005783 ISO     COP9 signalosome GO:0008180 ISO     extracellular exosome GO:0070062 ISO     membrane GO:0016020 ISO     myelin sheath GO:0043209 IDA     endoplasmic reticulum membrane GO:0005789 IDA     integral component of endoplasmic reticulum membrane GO:0030176 ISO