Gene description for Pdia2
Gene name protein disulfide isomerase associated 2
Gene symbol Pdia2
Other names/aliases 1810041F13Rik
AI661267
Pdip
Pdipl
Species Mus musculus
 Database cross references - Pdia2
ExoCarta ExoCarta_69191
Entrez Gene 69191
UniProt D3Z6P0  
 Pdia2 identified in exosomes derived from the following tissue/cell type
Brain cancer cells 19109410    
 Gene ontology annotations for Pdia2
Molecular Function
    lipid binding GO:0008289 IEA
    peptidyl-proline 4-dioxygenase activity GO:0031545 IBA
    isomerase activity GO:0016853 IEA
    protein disulfide isomerase activity GO:0003756 TAS
    steroid binding GO:0005496 IEA
Biological Process
    response to endoplasmic reticulum stress GO:0034976 IBA
    regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902175 IBA
    cell redox homeostasis GO:0045454 IEA
    protein folding GO:0006457 TAS
Subcellular Localization
    endoplasmic reticulum GO:0005783 IEA
 Experiment description of studies that identified Pdia2 in exosomes
1
Experiment ID 26
ISEV standards
EM
EV Biophysical techniques
Alix|GAPDH|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19109410    
Organism Mus musculus
Experiment description Proteomic and immunologic analyses of brain tumor exosomes.
Authors Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD
Journal name FASEB
Publication year 2008
Sample Brain cancer cells
Sample name SMA560vIII
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
 Protein-protein interactions for Pdia2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pdia2 is involved
No pathways found





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