Gene description for Pdia4
Gene name protein disulfide isomerase associated 4
Gene symbol Pdia4
Other names/aliases AI987846
Cai
ERp-72
Erp72
Species Mus musculus
 Database cross references - Pdia4
ExoCarta ExoCarta_12304
Entrez Gene 12304
UniProt P08003  
 Pdia4 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Pdia4
Molecular Function
    isomerase activity GO:0016853 IEA
    poly(A) RNA binding GO:0044822 ISO
    protein disulfide isomerase activity GO:0003756 ISO
Biological Process
    protein folding GO:0006457 IBA
    response to endoplasmic reticulum stress GO:0034976 IBA
    cell redox homeostasis GO:0045454 IEA
    chaperone-mediated protein folding GO:0061077 ISO
    positive regulation of protein folding GO:1903334 ISO
Subcellular Localization
    endoplasmic reticulum chaperone complex GO:0034663 IDA
    cell surface GO:0009986 ISO
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum lumen GO:0005788 IEA
    smooth endoplasmic reticulum GO:0005790 ISO
 Experiment description of studies that identified Pdia4 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pdia4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pdia4 is involved
No pathways found





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