Gene description for BRIX1
Gene name
BRX1, biogenesis of ribosomes
Gene symbol
BRIX1
Other names/aliases
BRIX BXDC2
Species
Homo sapiens
Database cross references - BRIX1
ExoCarta
ExoCarta_55299
Entrez Gene
55299
HGNC
24170
UniProt
Q8TDN6
BRIX1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for BRIX1
Experiment description of studies that identified BRIX1 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for BRIX1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ZNF9
Affinity Capture-MS
Homo sapiens
2
LYAR
55646
Affinity Capture-MS
Homo sapiens
3
UBA2
10054
Two-hybrid
Homo sapiens
4
CDC42BPB
9578
Affinity Capture-MS
Homo sapiens
5
UNC119
Two-hybrid
Homo sapiens
6
CD48
962
Two-hybrid
Homo sapiens
7
SETDB1
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which BRIX1 is involved
No pathways found