Gene description for APOBEC3C
Gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Gene symbol APOBEC3C
Other names/aliases A3C
APOBEC1L
ARDC2
ARDC4
ARP5
PBI
bK150C2.3
Species Homo sapiens
 Database cross references - APOBEC3C
ExoCarta ExoCarta_27350
Vesiclepedia VP_27350
Entrez Gene 27350
HGNC 17353
MIM 607750
UniProt Q9NRW3  
 APOBEC3C identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for APOBEC3C
Molecular Function
    zinc ion binding GO:0008270 IEA
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 IDA
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 IEA
Biological Process
    negative regulation of viral genome replication GO:0045071 IDA
    negative regulation of transposition GO:0010529 IDA
    DNA demethylation GO:0080111 IDA
    viral process GO:0016032 IEA
    innate immune response GO:0045087 IEA
    cytidine deamination GO:0009972 IDA
    defense response to virus GO:0051607 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified APOBEC3C in exosomes
1
Experiment ID 488
MISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 217
MISEV standards
EM
EV Biophysical techniques
TSG101|CD81|CD9|CD63
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for APOBEC3C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CNBP 7555
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which APOBEC3C is involved
No pathways found





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