Experiment description of studies that identified SHBG in exosomes

1 Experiment ID 275 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81 Enriched markers ✔ AIF Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25844599     Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T." Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 - Docetaxel sensitive Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry/Flow cytometry/Western blotting

2 Experiment ID 274 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81 Enriched markers ✔ AIF Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25844599     Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T." Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 - Docetaxel resistant Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Flow cytometry Western blotting

Protein-protein interactions for SHBG

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PACSIN2 11252 Two-hybrid Homo sapiens 2 DDX3Y 8653 Two-hybrid Homo sapiens 3 SEMA3F 6405 Two-hybrid Homo sapiens 4 AK2 204 Two-hybrid Homo sapiens 5 GRB2 2885 Two-hybrid Homo sapiens 6 EEF1A1 1915 Two-hybrid Homo sapiens 7 PTGDS   Two-hybrid Homo sapiens 8 MXD4 10608 Two-hybrid Homo sapiens 9 PLA2G4A 5321 Two-hybrid Homo sapiens 10 PKM 5315 Two-hybrid Homo sapiens 11 ACTA2 59 Two-hybrid Homo sapiens 12 KEAP1 9817 Negative Genetic Homo sapiens 13 ATP5A1 498 Two-hybrid Homo sapiens 14 CTSD 1509 Two-hybrid Homo sapiens 15 RMND5B   Two-hybrid Homo sapiens 16 TMEM236   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 UBE3A 7337 Two-hybrid Homo sapiens 18 COL1A2 1278 Two-hybrid Homo sapiens 19 MT2A 4502 Two-hybrid Homo sapiens 20 SRF   Two-hybrid Homo sapiens 21 AZGP1 563 Two-hybrid Homo sapiens 22 A2M 2 Two-hybrid Homo sapiens 23 APOD 347 Two-hybrid Homo sapiens 24 AKR1B1 231 Two-hybrid Homo sapiens 25 APOBEC3C 27350 Two-hybrid Homo sapiens 26 CECR5 27440 Two-hybrid Homo sapiens 27 NF1 4763 Negative Genetic Homo sapiens 28 PSTPIP1 9051 Two-hybrid Homo sapiens 29 ASB16-AS1   Two-hybrid Homo sapiens 30 SNRNP70 6625 Two-hybrid Homo sapiens 31 CLEC4G   Two-hybrid Homo sapiens 32 DES 1674 Two-hybrid Homo sapiens 33 MT1F   Two-hybrid Homo sapiens 34 DSTN 11034 Two-hybrid Homo sapiens 35 CNTNAP3B   Affinity Capture-MS Homo sapiens 36 NOMO1 23420 Two-hybrid Homo sapiens 37 KLK4   Two-hybrid Homo sapiens 38 FLOT1 10211 Two-hybrid Homo sapiens 39 UBE2O 63893 Two-hybrid Homo sapiens 40 APEH 327 Two-hybrid Homo sapiens 41 AP2A1 160 Two-hybrid Homo sapiens 42 AP1B1 162 Two-hybrid Homo sapiens 43 FLNA 2316 Two-hybrid Homo sapiens 44 HYI 81888 Two-hybrid Homo sapiens 45 ACPP 55 Two-hybrid Homo sapiens 46 ACTG2 72 Two-hybrid Homo sapiens 47 ACTB 60 Two-hybrid Homo sapiens 48 PLP2 5355 Two-hybrid Homo sapiens 49 FYTTD1   Two-hybrid Homo sapiens 50 SHBG 6462 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 51 CLDN4 1364 Two-hybrid Homo sapiens 52 SORD 6652 Two-hybrid Homo sapiens 53 SLC37A4 2542 Two-hybrid Homo sapiens 54 TINAGL1 64129 Two-hybrid Homo sapiens 55 MPDU1 9526 Two-hybrid Homo sapiens 56 EIF3E 3646 Two-hybrid Homo sapiens 57 MT1G 4495 Two-hybrid Homo sapiens 58 SRI 6717 Two-hybrid Homo sapiens 59 CD177   Two-hybrid Homo sapiens 60 GNB2 2783 Affinity Capture-MS Homo sapiens View the network

Pathways in which SHBG is involved

No pathways found