Gene description for SEMA3F
Gene name sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Gene symbol SEMA3F
Other names/aliases SEMA-IV
SEMA4
SEMAK
Species Homo sapiens
 Database cross references - SEMA3F
ExoCarta ExoCarta_6405
Entrez Gene 6405
HGNC 10728
MIM 601124
UniProt Q13275  
 SEMA3F identified in exosomes derived from the following tissue/cell type
Keratinocytes 19530224    
Keratinocytes 19530224    
 Gene ontology annotations for SEMA3F
Molecular Function
    chemorepellent activity GO:0045499 IDA
Biological Process
    negative chemotaxis GO:0050919 IEA
    sympathetic neuron projection extension GO:0097490 ISS
    facial nerve structural organization GO:0021612 IEA
    semaphorin-plexin signaling pathway involved in axon guidance GO:1902287 IEA
    ventral trunk neural crest cell migration GO:0036486 IEA
    semaphorin-plexin signaling pathway involved in neuron projection guidance GO:1902285 ISS
    trigeminal nerve structural organization GO:0021637 IEA
    sympathetic ganglion development GO:0061549 ISS
    negative regulation of axon extension involved in axon guidance GO:0048843 IEA
    axon guidance GO:0007411 IDA
    axon extension involved in axon guidance GO:0048846 ISS
    sympathetic neuron projection guidance GO:0097491 ISS
    neural crest cell migration involved in autonomic nervous system development GO:1901166 IEA
    branchiomotor neuron axon guidance GO:0021785 IEA
    nerve development GO:0021675 ISS
Subcellular Localization
    extracellular space GO:0005615 TAS
 Experiment description of studies that identified SEMA3F in exosomes
1
Experiment ID 189
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 190
ISEV standards
EM
EV Biophysical techniques
HSC70
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SEMA3F
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 VEGF  
Invitro Homo sapiens
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which SEMA3F is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here