Gene description for ZNF768
Gene name zinc finger protein 768
Gene symbol ZNF768
Other names/aliases -
Species Homo sapiens
 Database cross references - ZNF768
ExoCarta ExoCarta_79724
Entrez Gene 79724
HGNC 26273
UniProt Q9H5H4  
 ZNF768 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZNF768
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    metal ion binding GO:0046872 IEA
    DNA binding GO:0003677 IEA
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    transcription from RNA polymerase II promoter GO:0006366 IEA
Subcellular Localization
    DNA-directed RNA polymerase II, core complex GO:0005665 IEA
 Experiment description of studies that identified ZNF768 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZNF768
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZNF768 is involved
No pathways found





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