Gene description for ZNF768
Gene name zinc finger protein 768
Gene symbol ZNF768
Other names/aliases -
Species Homo sapiens
 Database cross references - ZNF768
ExoCarta ExoCarta_79724
Vesiclepedia VP_79724
Entrez Gene 79724
HGNC 26273
UniProt Q9H5H4  
 ZNF768 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZNF768
Molecular Function
    RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000977 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
    sequence-specific double-stranded DNA binding GO:1990837 IDA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    transcription by RNA polymerase II GO:0006366 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    chromosome GO:0005694 IEA
 Experiment description of studies that identified ZNF768 in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZNF768
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HMP19  
Two-hybrid Homo sapiens
2 RPSA 3921
Affinity Capture-MS Homo sapiens
3 RPSAP58 388524
Affinity Capture-MS Homo sapiens
4 Hax1  
Affinity Capture-MS Mus musculus
5 ZNF346  
Affinity Capture-MS Homo sapiens
6 IPO7 10527
Affinity Capture-MS Homo sapiens
7 RPL13A 23521
Affinity Capture-MS Homo sapiens
8 TRIM66  
Affinity Capture-MS Homo sapiens
9 RPS19 6223
Affinity Capture-MS Homo sapiens
10 Ndc80  
Affinity Capture-MS Mus musculus
11 RPL14 9045
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 RPS3 6188
Affinity Capture-MS Homo sapiens
13 ZNF648  
Two-hybrid Homo sapiens
14 KLF8  
Affinity Capture-MS Homo sapiens
15 UBE2O 63893
Affinity Capture-MS Homo sapiens
16 CCDC137  
Affinity Capture-MS Homo sapiens
17 SCRIB 23513
Affinity Capture-MS Homo sapiens
18 ANOS1 3730
Affinity Capture-MS Homo sapiens
19 FBLN2 2199
Affinity Capture-MS Homo sapiens
20 BRPF3  
Affinity Capture-MS Homo sapiens
21 KLF15  
Affinity Capture-MS Homo sapiens
22 EWSR1 2130
Affinity Capture-MS Homo sapiens
23 MDC1  
Affinity Capture-MS Homo sapiens
24 ADARB1 104
Affinity Capture-MS Homo sapiens
25 EFEMP1 2202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 PRKRA 8575
Affinity Capture-MS Homo sapiens
27 TIMM50 92609
Affinity Capture-MS Homo sapiens
28 MYCN  
Affinity Capture-MS Homo sapiens
29 SDCBP 6386
Two-hybrid Homo sapiens
30 RPL19 6143
Affinity Capture-MS Homo sapiens
31 NOTCH2 4853
Affinity Capture-MS Homo sapiens
32 LIN28A  
Affinity Capture-MS Homo sapiens
33 KLF16  
Affinity Capture-MS Homo sapiens
34 CLK2 1196
Two-hybrid Homo sapiens
35 ZNF277  
Two-hybrid Homo sapiens
36 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
37 ZNF330  
Two-hybrid Homo sapiens
38 PARK2  
Affinity Capture-MS Homo sapiens
39 RPS10 6204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 TRA2A 29896
Affinity Capture-MS Homo sapiens
41 YBX2 51087
Affinity Capture-MS Homo sapiens
42 KRTAP10-1  
Two-hybrid Homo sapiens
43 NONO 4841
Affinity Capture-MS Homo sapiens
44 APOBEC3C 27350
Affinity Capture-MS Homo sapiens
45 SRSF6 6431
Affinity Capture-MS Homo sapiens
46 Rad21  
Affinity Capture-MS Mus musculus
47 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
48 SRSF4 6429
Affinity Capture-MS Homo sapiens
49 BARD1 580
Affinity Capture-MS Homo sapiens
50 OGT 8473
Reconstituted Complex Homo sapiens
51 CECR2  
Affinity Capture-MS Homo sapiens
52 KMT2E  
Affinity Capture-MS Homo sapiens
53 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
54 REXO4  
Affinity Capture-MS Homo sapiens
55 LTBP2 4053
Affinity Capture-MS Homo sapiens
56 RPL36 25873
Affinity Capture-MS Homo sapiens
57 HECTD1 25831
Affinity Capture-MS Homo sapiens
58 RPLP0 6175
Affinity Capture-MS Homo sapiens
59 MAGEB2 4113
Affinity Capture-MS Homo sapiens
60 FGF13  
Affinity Capture-MS Homo sapiens
61 SP100 6672
Affinity Capture-MS Homo sapiens
62 KDF1  
Affinity Capture-MS Homo sapiens
63 FGFBP1 9982
Affinity Capture-MS Homo sapiens
64 C1QTNF2  
Affinity Capture-MS Homo sapiens
65 SFPQ 6421
Affinity Capture-MS Homo sapiens
66 ZBTB2 57621
Affinity Capture-MS Homo sapiens
67 ABT1 29777
Affinity Capture-MS Homo sapiens
68 SORT1 6272
Affinity Capture-MS Homo sapiens
69 ATL3 25923
Affinity Capture-MS Homo sapiens
70 RPS2 6187
Affinity Capture-MS Homo sapiens
71 RPL35 11224
Affinity Capture-MS Homo sapiens
72 NPM3 10360
Affinity Capture-MS Homo sapiens
73 CUL3 8452
Affinity Capture-MS Homo sapiens
74 SGOL1  
Affinity Capture-MS Homo sapiens
75 SRSF5 6430
Affinity Capture-MS Homo sapiens
76 RPL3 6122
Affinity Capture-MS Homo sapiens
77 ZNF835  
Two-hybrid Homo sapiens
78 ZNF250  
Two-hybrid Homo sapiens
79 BRD1 23774
Affinity Capture-MS Homo sapiens
80 PSPC1 55269
Affinity Capture-MS Homo sapiens
81 INO80B 83444
Affinity Capture-MS Homo sapiens
82 DDRGK1 65992
Affinity Capture-MS Homo sapiens
83 MRPS17 51373
Affinity Capture-MS Homo sapiens
84 ZNF417  
Two-hybrid Homo sapiens
85 PASK  
Affinity Capture-MS Homo sapiens
86 DOCK3  
Affinity Capture-MS Homo sapiens
87 RPL11 6135
Affinity Capture-MS Homo sapiens
88 TNNT1  
Two-hybrid Homo sapiens
89 ZNF574  
Affinity Capture-MS Homo sapiens
90 RPL13 6137
Affinity Capture-MS Homo sapiens
91 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
92 SLC16A6 9120
Affinity Capture-MS Homo sapiens
93 FBXL6  
Affinity Capture-MS Homo sapiens
94 LDLRAD1  
Affinity Capture-MS Homo sapiens
95 PIN1 5300
Two-hybrid Homo sapiens
96 RPS8 6202
Affinity Capture-MS Homo sapiens
97 NDUFA12 55967
Two-hybrid Homo sapiens
98 TDRD7 23424
Affinity Capture-MS Homo sapiens
99 UFL1 23376
Affinity Capture-MS Homo sapiens
100 NEIL1  
Affinity Capture-MS Homo sapiens
101 RPL7A 6130
Affinity Capture-MS Homo sapiens
102 RPS6 6194
Affinity Capture-MS Homo sapiens
103 RPL8 6132
Affinity Capture-MS Homo sapiens
104 RPL28 6158
Affinity Capture-MS Homo sapiens
105 ORC1  
Affinity Capture-MS Homo sapiens
106 Tnpo1 238799
Affinity Capture-MS Mus musculus
107 RPL23A 6147
Affinity Capture-MS Homo sapiens
108 RPL36AL 6166
Affinity Capture-MS Homo sapiens
109 RBM34  
Affinity Capture-MS Homo sapiens
110 EMG1 10436
Two-hybrid Homo sapiens
111 ZNF467  
Affinity Capture-MS Homo sapiens
112 EFEMP2 30008
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF768 is involved
No pathways found





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