Gene description for LTBP2
Gene name latent transforming growth factor beta binding protein 2
Gene symbol LTBP2
Other names/aliases C14orf141
GLC3D
LTBP3
MSPKA
MSTP031
WMS3
Species Homo sapiens
 Database cross references - LTBP2
ExoCarta ExoCarta_4053
Entrez Gene 4053
HGNC 6715
MIM 602091
UniProt Q14767  
 LTBP2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for LTBP2
Molecular Function
    calcium ion binding GO:0005509 IEA
    growth factor binding GO:0019838 IEA
    heparin binding GO:0008201 IEA
    protein binding GO:0005515 IPI
Biological Process
    protein targeting GO:0006605 TAS
    protein secretion GO:0009306 TAS
    transforming growth factor beta receptor signaling pathway GO:0007179 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    extracellular space GO:0005615 IDA
    proteinaceous extracellular matrix GO:0005578 TAS
    intracellular GO:0005622 TAS
    cell GO:0005623 TAS
    extracellular matrix GO:0031012 IDA
 Experiment description of studies that identified LTBP2 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for LTBP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LTBP2 is involved
PathwayEvidenceSource
Molecules associated with elastic fibres TAS Reactome





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