Gene description for ZNF358
Gene name zinc finger protein 358
Gene symbol ZNF358
Other names/aliases ZFEND
Species Homo sapiens
 Database cross references - ZNF358
ExoCarta ExoCarta_140467
Vesiclepedia VP_140467
Entrez Gene 140467
HGNC 16838
UniProt Q9NW07  
 ZNF358 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZNF358
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity GO:0003700 IBA
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    stem cell population maintenance GO:0019827 ISS
    neural tube development GO:0021915 ISS
    embryonic forelimb morphogenesis GO:0035115 ISS
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified ZNF358 in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZNF358
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 RPS3 6188
Affinity Capture-MS Homo sapiens
3 VWCE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 RPL23A 6147
Affinity Capture-MS Homo sapiens
5 FBLN2 2199
Affinity Capture-MS Homo sapiens
6 HECTD1 25831
Affinity Capture-MS Homo sapiens
7 MYCN  
Affinity Capture-MS Homo sapiens
8 LTBP2 4053
Affinity Capture-MS Homo sapiens
9 FAM170A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 PTTG1  
Synthetic Growth Defect Homo sapiens
11 KCTD17 79734
Affinity Capture-MS Homo sapiens
12 EFEMP1 2202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 MUS81  
Synthetic Growth Defect Homo sapiens
14 FGF13  
Affinity Capture-MS Homo sapiens
15 RPL17 6139
Affinity Capture-MS Homo sapiens
16 RPS10 6204
Affinity Capture-MS Homo sapiens
17 NOTCH2 4853
Affinity Capture-MS Homo sapiens
18 SRSF6 6431
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF358 is involved
No pathways found





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