Gene description for ZNF358
Gene name zinc finger protein 358
Gene symbol ZNF358
Other names/aliases ZFEND
Species Homo sapiens
 Database cross references - ZNF358
ExoCarta ExoCarta_140467
Entrez Gene 140467
HGNC 16838
UniProt Q9NW07  
 ZNF358 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZNF358
Molecular Function
    DNA binding GO:0003677 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    transcription, DNA-templated GO:0006351 IEA
    stem cell maintenance GO:0019827 ISS
    regulation of transcription, DNA-templated GO:0006355 IEA
    neural tube development GO:0021915 ISS
    embryonic forelimb morphogenesis GO:0035115 ISS
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified ZNF358 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZNF358
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZNF358 is involved
No pathways found





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