Gene description for NPM3
Gene name nucleophosmin/nucleoplasmin 3
Gene symbol NPM3
Other names/aliases PORMIN
TMEM123
Species Homo sapiens
 Database cross references - NPM3
ExoCarta ExoCarta_10360
Vesiclepedia VP_10360
Entrez Gene 10360
HGNC 7931
MIM 606456
UniProt O75607  
 NPM3 identified in sEVs derived from the following tissue/cell type
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for NPM3
Molecular Function
    chromatin binding GO:0003682 IBA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    protein binding GO:0005515 IPI
    histone binding GO:0042393 IBA
Biological Process
    chromatin remodeling GO:0006338 IBA
    rRNA processing GO:0006364 IEA
    rRNA transcription GO:0009303 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IBA
    nucleolus GO:0005730 IBA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
    actin cytoskeleton GO:0015629 IDA
 Experiment description of studies that identified NPM3 in sEVs
1
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
2
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
3
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
5
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NPM3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 RPP14  
Affinity Capture-MS Homo sapiens
4 ZNF668  
Affinity Capture-MS Homo sapiens
5 SSR4 6748
Affinity Capture-MS Homo sapiens
6 SENP3 26168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 RPL26L1 51121
Affinity Capture-MS Homo sapiens
8 ZNF16  
Affinity Capture-MS Homo sapiens
9 KPNA3 3839
Affinity Capture-MS Homo sapiens
10 DDX24 57062
Affinity Capture-MS Homo sapiens
11 AATF  
Affinity Capture-MS Homo sapiens
12 EEF1G 1937
Co-fractionation Homo sapiens
13 RPS3A 6189
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 MRPS18B 28973
Affinity Capture-MS Homo sapiens
15 KIAA0020 9933
Affinity Capture-MS Homo sapiens
16 RSL24D1  
Affinity Capture-MS Homo sapiens
17 TPD52L1 7164
Co-fractionation Homo sapiens
18 YWHAE 7531
Co-fractionation Homo sapiens
19 RPL13A 23521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 RPL37A 6168
Affinity Capture-MS Homo sapiens
21 URB1 9875
Affinity Capture-MS Homo sapiens
22 EPB41L5 57669
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 NMNAT1  
Affinity Capture-MS Homo sapiens
24 RPL10 6134
Affinity Capture-MS Homo sapiens
25 RPL15 6138
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 HSP90AB1 3326
Co-fractionation Homo sapiens
27 MRPS17 51373
Affinity Capture-MS Homo sapiens
28 PRPF40A 55660
Co-fractionation Homo sapiens
29 MRPS27 23107
Affinity Capture-MS Homo sapiens
30 WDR36 134430
Affinity Capture-MS Homo sapiens
31 USP36  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 ZNF70  
Affinity Capture-MS Homo sapiens
33 NPM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
34 NTN1 9423
Affinity Capture-MS Homo sapiens
35 RPL10A 4736
Affinity Capture-MS Homo sapiens
36 MRPL20 55052
Affinity Capture-MS Homo sapiens
37 WHSC1 7468
Affinity Capture-MS Homo sapiens
38 MRPS23 51649
Affinity Capture-MS Homo sapiens
39 MCM2 4171
Affinity Capture-MS Homo sapiens
40 WT1  
Two-hybrid Homo sapiens
41 WDR74 54663
Affinity Capture-MS Homo sapiens
42 CCDC137  
Affinity Capture-MS Homo sapiens
43 IMP3 55272
Affinity Capture-MS Homo sapiens
44 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
45 AP1G1 164
Co-fractionation Homo sapiens
46 NPM1 4869
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
48 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 WDR12 55759
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 RECQL4  
Affinity Capture-MS Homo sapiens
51 KRI1  
Affinity Capture-MS Homo sapiens
52 RPS9 6203
Affinity Capture-MS Homo sapiens
53 MAGED2 10916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 NSUN4  
Affinity Capture-MS Homo sapiens
55 RPF2 84154
Affinity Capture-MS Homo sapiens
56 TTF1  
Affinity Capture-MS Homo sapiens
57 PAK1IP1  
Affinity Capture-MS Homo sapiens
58 PRKRA 8575
Affinity Capture-MS Homo sapiens
59 DDX51  
Affinity Capture-MS Homo sapiens
60 NIFK 84365
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 EED  
Affinity Capture-MS Homo sapiens
62 ABT1 29777
Affinity Capture-MS Homo sapiens
63 Naa11  
Affinity Capture-MS Mus musculus
64 ATG16L1 55054
Affinity Capture-MS Homo sapiens
65 SENP5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 RPL34 6164
Affinity Capture-MS Homo sapiens
67 Eif3a 13669
Affinity Capture-MS Mus musculus
68 DNM1 1759
Co-fractionation Homo sapiens
69 MAK16  
Affinity Capture-MS Homo sapiens
70 C18orf21  
Affinity Capture-MS Homo sapiens
71 RPL19 6143
Affinity Capture-MS Homo sapiens
72 CTCF  
Affinity Capture-MS Homo sapiens
73 PES1 23481
Affinity Capture-MS Homo sapiens
74 FAS 355
Proximity Label-MS Homo sapiens
75 BRIX1 55299
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 RPL27 6155
Affinity Capture-MS Homo sapiens
77 DDX31  
Affinity Capture-MS Homo sapiens
78 PNO1 56902
Affinity Capture-MS Homo sapiens
79 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
80 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
81 DDX21 9188
Affinity Capture-MS Homo sapiens
82 RPL9 6133
Affinity Capture-MS Homo sapiens
83 RPL4 6124
Affinity Capture-MS Homo sapiens
84 RBM28 55131
Affinity Capture-MS Homo sapiens
85 CENPV 201161
Affinity Capture-MS Homo sapiens
86 IRF2BPL 64207
Co-fractionation Homo sapiens
87 XRN1 54464
Affinity Capture-MS Homo sapiens
88 STAU1 6780
Affinity Capture-MS Homo sapiens
89 NOP2 4839
Affinity Capture-MS Homo sapiens
90 ZNF22  
Affinity Capture-MS Homo sapiens
91 RPL5 6125
Affinity Capture-MS Homo sapiens
92 NOL7  
Affinity Capture-MS Homo sapiens
93 DDX10  
Affinity Capture-MS Homo sapiens
94 SP110  
Affinity Capture-MS Homo sapiens
95 BARD1 580
Affinity Capture-MS Homo sapiens
96 TRIM21 6737
Affinity Capture-MS Homo sapiens
97 NKRF 55922
Affinity Capture-MS Homo sapiens
98 RPL31 6160
Proximity Label-MS Homo sapiens
99 LAS1L 81887
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 NOP16 51491
Affinity Capture-MS Homo sapiens
101 REXO4  
Affinity Capture-MS Homo sapiens
102 WDR43 23160
Affinity Capture-MS Homo sapiens
103 HJURP  
Affinity Capture-MS Homo sapiens
104 SDAD1  
Affinity Capture-MS Homo sapiens
105 RPLP0 6175
Affinity Capture-MS Homo sapiens
106 RRP1B 23076
Affinity Capture-MS Homo sapiens
107 PELP1 27043
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 FAM120A 23196
Co-fractionation Homo sapiens
109 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
110 DDX27 55661
Affinity Capture-MS Homo sapiens
111 GTPBP4 23560
Affinity Capture-MS Homo sapiens
112 ATP5B 506
Co-fractionation Homo sapiens
113 GLTSCR2  
Affinity Capture-MS Homo sapiens
114 C7orf50 84310
Affinity Capture-MS Homo sapiens
115 RPF1  
Affinity Capture-MS Homo sapiens
116 DDX18 8886
Affinity Capture-MS Homo sapiens
117 RSL1D1 26156
Affinity Capture-MS Homo sapiens
118 CCDC59  
Affinity Capture-MS Homo sapiens
119 RRP8  
Affinity Capture-MS Homo sapiens
120 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
121 RPL32 6161
Affinity Capture-MS Homo sapiens
122 ASCC3 10973
Affinity Capture-MS Homo sapiens
123 RHOU 58480
Reconstituted Complex Homo sapiens
124 BMS1  
Affinity Capture-MS Homo sapiens
125 RPLP2 6181
Affinity Capture-MS Homo sapiens
126 NOC3L 64318
Affinity Capture-MS Homo sapiens
127 POP1 10940
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 ZBTB24  
Affinity Capture-MS Homo sapiens
129 GLE1 2733
Affinity Capture-MS Homo sapiens
130 POP5  
Affinity Capture-MS Homo sapiens
131 NAT10 55226
Affinity Capture-MS Homo sapiens
132 SCML1  
Affinity Capture-MS Homo sapiens
133 SRSF5 6430
Affinity Capture-MS Homo sapiens
134 TAF1B  
Affinity Capture-MS Homo sapiens
135 ZNF624 57547
Affinity Capture-MS Homo sapiens
136 PRKCZ 5590
Affinity Capture-MS Homo sapiens
137 RPL14 9045
Affinity Capture-MS Homo sapiens
138 RPP38 10557
Affinity Capture-MS Homo sapiens
139 RPS6 6194
Proximity Label-MS Homo sapiens
140 WDR55  
Affinity Capture-MS Homo sapiens
141 RPL3 6122
Affinity Capture-MS Homo sapiens
142 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 PAPD5 64282
Affinity Capture-MS Homo sapiens
144 FAM111A 63901
Affinity Capture-MS Homo sapiens
145 KIAA1377  
Two-hybrid Homo sapiens
146 RPL7L1 285855
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 NIP7 51388
Affinity Capture-MS Homo sapiens
148 ZC3H10  
Affinity Capture-MS Homo sapiens
149 RPP30 10556
Affinity Capture-MS Homo sapiens
150 ZNF512  
Affinity Capture-MS Homo sapiens
151 MRPL24  
Affinity Capture-MS Homo sapiens
152 RPP25  
Affinity Capture-MS Homo sapiens
153 CEBPZ  
Affinity Capture-MS Homo sapiens
154 RPP40 10799
Affinity Capture-MS Homo sapiens
155 NOL12 79159
Affinity Capture-MS Homo sapiens
156 RPL12 6136
Affinity Capture-MS Homo sapiens
157 DDX54 79039
Affinity Capture-MS Homo sapiens
158 HP1BP3 50809
Affinity Capture-MS Homo sapiens
159 RPL18 6141
Affinity Capture-MS Homo sapiens
160 DDRGK1 65992
Affinity Capture-MS Homo sapiens
161 RRS1 23212
Affinity Capture-MS Homo sapiens
162 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
163 Rpl35 66489
Affinity Capture-MS Mus musculus
164 ARGLU1  
Co-fractionation Homo sapiens
165 ZFP62  
Affinity Capture-MS Homo sapiens
166 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
167 MRPL47 57129
Affinity Capture-MS Homo sapiens
168 FTSJ3 117246
Affinity Capture-MS Homo sapiens
169 KIAA1522 57648
Affinity Capture-MS Homo sapiens
170 C3orf17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 H2AFX 3014
Affinity Capture-MS Homo sapiens
172 ZNF184  
Affinity Capture-MS Homo sapiens
173 ZNF574  
Affinity Capture-MS Homo sapiens
174 RRP15  
Affinity Capture-MS Homo sapiens
175 RPL13 6137
Affinity Capture-MS Homo sapiens
176 DDX50 79009
Affinity Capture-MS Homo sapiens
177 SURF6  
Affinity Capture-MS Homo sapiens
178 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
179 EPB41L4B 54566
Affinity Capture-MS Homo sapiens
180 TAF1A  
Affinity Capture-MS Homo sapiens
181 KTN1 3895
Affinity Capture-MS Homo sapiens
182 FBXL6  
Affinity Capture-MS Homo sapiens
183 RPL6 6128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 PRDM15  
Affinity Capture-MS Homo sapiens
185 NLE1 54475
Affinity Capture-MS Homo sapiens
186 MINA 84864
Affinity Capture-MS Homo sapiens
187 NOL10  
Affinity Capture-MS Homo sapiens
188 BOP1 23246
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 PDCD4 27250
Affinity Capture-MS Homo sapiens
190 POP4 10775
Affinity Capture-MS Homo sapiens
191 HNRNPM 4670
Affinity Capture-MS Homo sapiens
192 RPS15 6209
Affinity Capture-MS Homo sapiens
193 SRP72 6731
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 RPP25L  
Affinity Capture-MS Homo sapiens
195 NSA2  
Affinity Capture-MS Homo sapiens
196 TAF1D  
Affinity Capture-MS Homo sapiens
197 MKI67  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 NOL9 79707
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 WDR18 57418
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 UFL1 23376
Affinity Capture-MS Homo sapiens
201 RPS20 6224
Affinity Capture-MS Homo sapiens
202 NOC2L 26155
Affinity Capture-MS Homo sapiens
203 MRPL41 64975
Affinity Capture-MS Homo sapiens
204 NCL 4691
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
205 YBX3 8531
Affinity Capture-MS Homo sapiens
206 ZNF768 79724
Affinity Capture-MS Homo sapiens
207 RPL23AP32 56969
Affinity Capture-MS Homo sapiens
208 C14orf169  
Affinity Capture-MS Homo sapiens
209 Rrbp1  
Affinity Capture-MS Mus musculus
210 RPL8 6132
Affinity Capture-MS Homo sapiens
211 TAF1C  
Affinity Capture-MS Homo sapiens
212 RPL28 6158
Affinity Capture-MS Homo sapiens
213 GLYR1 84656
Affinity Capture-MS Homo sapiens
214 RPL11 6135
Affinity Capture-MS Homo sapiens
215 RPL23A 6147
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
216 HNRNPU 3192
Affinity Capture-MS Homo sapiens
217 RPL36AL 6166
Affinity Capture-MS Homo sapiens
218 RBM34  
Affinity Capture-MS Homo sapiens
219 TEX10 54881
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
220 NOP10 55505
Affinity Capture-MS Homo sapiens
221 NVL  
Affinity Capture-MS Homo sapiens
222 DDX56  
Affinity Capture-MS Homo sapiens
223 PRKRIR  
Affinity Capture-MS Homo sapiens
224 RPL17 6139
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 NHLH1  
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NPM3 is involved
No pathways found





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