Gene description for MRPS27
Gene name mitochondrial ribosomal protein S27
Gene symbol MRPS27
Other names/aliases MRP-S27
S27mt
Species Homo sapiens
 Database cross references - MRPS27
ExoCarta ExoCarta_23107
Vesiclepedia VP_23107
Entrez Gene 23107
HGNC 14512
MIM 611989
UniProt Q92552  
 MRPS27 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPS27
Molecular Function
    tRNA binding GO:0000049 IDA
    protein binding GO:0005515 IPI
    rRNA binding GO:0019843 IDA
    mitochondrial ribosome binding GO:0097177 IDA
Biological Process
    cell population proliferation GO:0008283 IMP
    mitochondrial translation GO:0032543 NAS
    positive regulation of mitochondrial translation GO:0070131 IMP
Subcellular Localization
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 IDA
    mitochondrial small ribosomal subunit GO:0005763 NAS
 Experiment description of studies that identified MRPS27 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPS27
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 SLIRP 81892
Proximity Label-MS Homo sapiens
4 Tmed2 56334
Affinity Capture-MS Mus musculus
5 TLX1  
Affinity Capture-MS Homo sapiens
6 PMPCA 23203
Proximity Label-MS Homo sapiens
7 NECAB2  
Two-hybrid Homo sapiens
8 Smc1a  
Affinity Capture-MS Mus musculus
9 COPS5 10987
Affinity Capture-MS Homo sapiens
10 TARDBP 23435
Affinity Capture-MS Homo sapiens
11 RPA2 6118
Proximity Label-MS Homo sapiens
12 LRRC15 131578
Affinity Capture-MS Homo sapiens
13 TRUB2  
Proximity Label-MS Homo sapiens
14 THOC2 57187
Affinity Capture-MS Homo sapiens
15 MTG2  
Proximity Label-MS Homo sapiens
16 NGRN  
Proximity Label-MS Homo sapiens
17 RPL10 6134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CHCHD1  
Proximity Label-MS Homo sapiens
19 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
20 DIAPH1 1729
Co-fractionation Homo sapiens
21 CAND1 55832
Affinity Capture-MS Homo sapiens
22 RPUSD4 84881
Proximity Label-MS Homo sapiens
23 DNAJC15  
Proximity Label-MS Homo sapiens
24 MTRF1  
Proximity Label-MS Homo sapiens
25 GFM2 84340
Proximity Label-MS Homo sapiens
26 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
27 CCDC90B  
Proximity Label-MS Homo sapiens
28 CENPA  
Affinity Capture-MS Homo sapiens
29 LRPPRC 10128
Proximity Label-MS Homo sapiens
30 KIAA1429 25962
Affinity Capture-MS Homo sapiens
31 CAPZB 832
Affinity Capture-MS Homo sapiens
32 RPL4 6124
Affinity Capture-MS Homo sapiens
33 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
34 EPDR1 54749
Affinity Capture-MS Homo sapiens
35 FERMT3 83706
Affinity Capture-MS Homo sapiens
36 CRYZ 1429
Proximity Label-MS Homo sapiens
37 TFAM 7019
Proximity Label-MS Homo sapiens
38 KIF23 9493
Affinity Capture-MS Homo sapiens
39 HINT2 84681
Proximity Label-MS Homo sapiens
40 TSNAX 7257
Affinity Capture-MS Homo sapiens
41 MRPS5 64969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 LUC7L3 51747
Co-fractionation Homo sapiens
43 C8orf82  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 MRPS23 51649
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
45 MRPS24 64951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 NPM1 4869
Affinity Capture-MS Homo sapiens
47 CALM3 808
Affinity Capture-MS Homo sapiens
48 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 DDRGK1 65992
Affinity Capture-MS Homo sapiens
50 KLF15  
Affinity Capture-MS Homo sapiens
51 MYCN  
Affinity Capture-MS Homo sapiens
52 MRPS26 64949
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 SURF1  
Proximity Label-MS Homo sapiens
54 SRSF3 6428
Affinity Capture-MS Homo sapiens
55 SNRNP48  
Two-hybrid Homo sapiens
56 EXD2  
Proximity Label-MS Homo sapiens
57 ERAL1  
Affinity Capture-MS Homo sapiens
58 KLF4  
Affinity Capture-MS Homo sapiens
59 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 MECP2 4204
Affinity Capture-MS Homo sapiens
61 TLX3  
Proximity Label-MS Homo sapiens
62 CUL1 8454
Affinity Capture-MS Homo sapiens
63 BTRC 8945
Affinity Capture-MS Homo sapiens
64 PMPCB 9512
Proximity Label-MS Homo sapiens
65 TACO1  
Proximity Label-MS Homo sapiens
66 FASTKD2  
Proximity Label-MS Homo sapiens
67 MTIF2 4528
Proximity Label-MS Homo sapiens
68 FAM120A 23196
Affinity Capture-MS Homo sapiens
69 MTERF3  
Proximity Label-MS Homo sapiens
70 CTCF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 KIF14 9928
Affinity Capture-MS Homo sapiens
72 GAR1 54433
Affinity Capture-MS Homo sapiens
73 LIN28A  
Affinity Capture-MS Homo sapiens
74 MDH2 4191
Proximity Label-MS Homo sapiens
75 SRSF6 6431
Affinity Capture-MS Homo sapiens
76 KLF16  
Affinity Capture-MS Homo sapiens
77 CHMP4C 92421
Affinity Capture-MS Homo sapiens
78 MRPS35 60488
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 HAUS2  
Affinity Capture-MS Homo sapiens
80 S100A2 6273
Affinity Capture-MS Homo sapiens
81 MRPS33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 C6orf203  
Proximity Label-MS Homo sapiens
83 C19orf52  
Proximity Label-MS Homo sapiens
84 COX15 1355
Proximity Label-MS Homo sapiens
85 FASTKD5  
Proximity Label-MS Homo sapiens
86 SRP14 6727
Affinity Capture-MS Homo sapiens
87 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 MRPS34 65993
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
89 ERBB3 2065
Affinity Capture-MS Homo sapiens
90 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
91 TRA2A 29896
Affinity Capture-MS Homo sapiens
92 TUFM 7284
Proximity Label-MS Homo sapiens
93 PTCD3 55037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 HSCB 150274
Proximity Label-MS Homo sapiens
95 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
96 SRSF7 6432
Affinity Capture-MS Homo sapiens
97 NTRK1 4914
Affinity Capture-MS Homo sapiens
98 MRPS6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 CCDC109B 55013
Proximity Label-MS Homo sapiens
100 ZSCAN26  
Affinity Capture-MS Homo sapiens
101 DNAJA1 3301
Co-fractionation Homo sapiens
102 GFM1 85476
Proximity Label-MS Homo sapiens
103 YWHAQ 10971
Reconstituted Complex Homo sapiens
104 MRPL3  
Affinity Capture-Western Homo sapiens
105 MCU 90550
Proximity Label-MS Homo sapiens
106 NOA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 RPS6 6194
Affinity Capture-MS Homo sapiens
108 MTFMT  
Proximity Label-MS Homo sapiens
109 MRPL11 65003
Proximity Label-MS Homo sapiens
110 CEP76  
Affinity Capture-MS Homo sapiens
111 PRKRIR  
Affinity Capture-MS Homo sapiens
112 TRIM31  
Affinity Capture-MS Homo sapiens
113 TMEM70  
Proximity Label-MS Homo sapiens
114 FBXO31 79791
Affinity Capture-MS Homo sapiens
115 GLTSCR2  
Affinity Capture-MS Homo sapiens
116 MRPL2 51069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 COX4I1 1327
Proximity Label-MS Homo sapiens
118 Cep131  
Affinity Capture-MS Mus musculus
119 ANLN 54443
Affinity Capture-MS Homo sapiens
120 MYH7B  
Affinity Capture-MS Homo sapiens
121 TLX2  
Proximity Label-MS Homo sapiens
122 MRPL12 6182
Affinity Capture-Western Homo sapiens
123 OTC 5009
Proximity Label-MS Homo sapiens
124 RBM39 9584
Affinity Capture-MS Homo sapiens
125 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
126 DNAJC21  
Affinity Capture-MS Homo sapiens
127 MRRF  
Proximity Label-MS Homo sapiens
128 ABT1 29777
Affinity Capture-MS Homo sapiens
129 MRPS12  
Proximity Label-MS Homo sapiens
130 AURKAIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 DAP3 7818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
132 DNAJC4  
Proximity Label-MS Homo sapiens
133 NR3C1 2908
Proximity Label-MS Homo sapiens
134 RC3H2  
Affinity Capture-MS Homo sapiens
135 ECT2 1894
Affinity Capture-MS Homo sapiens
136 YBX1 4904
Affinity Capture-MS Homo sapiens
137 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 MTIF3  
Proximity Label-MS Homo sapiens
139 RPL35 11224
Affinity Capture-MS Homo sapiens
140 DNAJC28  
Proximity Label-MS Homo sapiens
141 ZFR 51663
Affinity Capture-MS Homo sapiens
142 MRPS14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 SNX27 81609
Affinity Capture-MS Homo sapiens
144 NPM3 10360
Affinity Capture-MS Homo sapiens
145 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 RPUSD3  
Proximity Label-MS Homo sapiens
147 RMND1 55005
Proximity Label-MS Homo sapiens
148 ZEB1  
Affinity Capture-MS Homo sapiens
149 EGFR 1956
Negative Genetic Homo sapiens
150 THOC5 8563
Affinity Capture-MS Homo sapiens
151 GADD45GIP1  
Affinity Capture-MS Homo sapiens
152 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 DHX30 22907
Proximity Label-MS Homo sapiens
154 KBTBD7  
Affinity Capture-MS Homo sapiens
155 NXF1 10482
Affinity Capture-RNA Homo sapiens
156 MRPS28  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 AURKB 9212
Affinity Capture-MS Homo sapiens
158 C12orf65  
Proximity Label-MS Homo sapiens
159 FBXW11  
Affinity Capture-MS Homo sapiens
160 PRR3  
Affinity Capture-MS Homo sapiens
161 RBMS2 5939
Affinity Capture-MS Homo sapiens
162 MTG1  
Proximity Label-MS Homo sapiens
163 MYC  
Affinity Capture-MS Homo sapiens
164 RPA3 6119
Proximity Label-MS Homo sapiens
165 YBX3 8531
Affinity Capture-MS Homo sapiens
166 Mis12  
Affinity Capture-MS Mus musculus
167 NOL12 79159
Affinity Capture-MS Homo sapiens
168 TSFM 10102
Proximity Label-MS Homo sapiens
169 ACAD9 28976
Proximity Label-MS Homo sapiens
170 VWA8 23078
Proximity Label-MS Homo sapiens
171 CLPB 81570
Proximity Label-MS Homo sapiens
172 NOP16 51491
Affinity Capture-MS Homo sapiens
173 MRPS17 51373
Affinity Capture-MS Homo sapiens
174 Ufl1  
Affinity Capture-MS Mus musculus
175 METTL15  
Proximity Label-MS Homo sapiens
176 ZC3H3  
Affinity Capture-MS Homo sapiens
177 MCUR1 63933
Proximity Label-MS Homo sapiens
178 ILF3 3609
Co-fractionation Homo sapiens
179 SOX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 ZNF574  
Affinity Capture-MS Homo sapiens
181 HECTD1 25831
Affinity Capture-MS Homo sapiens
182 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 CLPP 8192
Proximity Label-MS Homo sapiens
184 GRK5 2869
Affinity Capture-MS Homo sapiens
185 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
186 ZNF707  
Affinity Capture-MS Homo sapiens
187 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
188 ESR2  
Affinity Capture-MS Homo sapiens
189 METTL17  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
190 AUH 549
Proximity Label-MS Homo sapiens
191 MRPS2 51116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 PDGFB  
Affinity Capture-MS Homo sapiens
193 HDGF 3068
Affinity Capture-MS Homo sapiens
194 DNAJC19 131118
Proximity Label-MS Homo sapiens
195 MCAT 27349
Affinity Capture-MS Homo sapiens
196 TP53 7157
Affinity Capture-MS Homo sapiens
197 RPL6 6128
Affinity Capture-MS Homo sapiens
198 MTRF1L  
Proximity Label-MS Homo sapiens
199 BYSL 705
Affinity Capture-MS Homo sapiens
200 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
201 SOX15  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 APOBEC3D  
Affinity Capture-MS Homo sapiens
203 ZNF746  
Affinity Capture-MS Homo sapiens
204 MRPS18C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 MRPS31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 LSM14A 26065
Affinity Capture-MS Homo sapiens
207 H1FNT  
Affinity Capture-MS Homo sapiens
208 PDHA1 5160
Proximity Label-MS Homo sapiens
209 DNAJA3 9093
Proximity Label-MS Homo sapiens
210 SMURF1 57154
Affinity Capture-MS Homo sapiens
211 RPS15 6209
Affinity Capture-MS Homo sapiens
212 MRPS15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
214 COX8A  
Proximity Label-MS Homo sapiens
215 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
216 MRPS10 55173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 LUC7L 55692
Affinity Capture-MS Homo sapiens
218