Gene description for MRPS2
Gene name mitochondrial ribosomal protein S2
Gene symbol MRPS2
Other names/aliases CGI-91
MRP-S2
S2mt
Species Homo sapiens
 Database cross references - MRPS2
ExoCarta ExoCarta_51116
Vesiclepedia VP_51116
Entrez Gene 51116
HGNC 14495
MIM 611971
UniProt Q9Y399  
 MRPS2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPS2
Molecular Function
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 ISS
Biological Process
    mitochondrial translation GO:0032543 ISS
    mitochondrial translation GO:0032543 NAS
    mitochondrial ribosome assembly GO:0061668 IMP
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial matrix GO:0005759 TAS
    mitochondrial small ribosomal subunit GO:0005763 IBA
    mitochondrial small ribosomal subunit GO:0005763 IDA
    mitochondrial small ribosomal subunit GO:0005763 ISS
    mitochondrial small ribosomal subunit GO:0005763 NAS
 Experiment description of studies that identified MRPS2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPS2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 CDC14B 8555
Affinity Capture-MS Homo sapiens
3 PDHA1 5160
Proximity Label-MS Homo sapiens
4 MRPS27 23107
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 SLIRP 81892
Proximity Label-MS Homo sapiens
6 FOXA1  
Affinity Capture-MS Homo sapiens
7 KLC2 64837
Affinity Capture-MS Homo sapiens
8 APOBEC3D  
Affinity Capture-MS Homo sapiens
9 RANBP10 57610
Affinity Capture-MS Homo sapiens
10 ADCK4 79934
Affinity Capture-MS Homo sapiens
11 TPD52L2 7165
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 RPA2 6118
Proximity Label-MS Homo sapiens
13 RPL26 6154
Affinity Capture-MS Homo sapiens
14 TRUB2  
Proximity Label-MS Homo sapiens
15 MTG2  
Proximity Label-MS Homo sapiens
16 NGRN  
Proximity Label-MS Homo sapiens
17 RPL10 6134
Affinity Capture-MS Homo sapiens
18 CHCHD1  
Proximity Label-MS Homo sapiens
19 KLF12  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MCCC1 56922
Affinity Capture-MS Homo sapiens
21 CAND1 55832
Affinity Capture-MS Homo sapiens
22 RPUSD4 84881
Proximity Label-MS Homo sapiens
23 DNAJC15  
Proximity Label-MS Homo sapiens
24 MTRF1  
Proximity Label-MS Homo sapiens
25 GFM2 84340
Proximity Label-MS Homo sapiens
26 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
27 CCDC90B  
Proximity Label-MS Homo sapiens
28 AMOTL1 154810
Affinity Capture-MS Homo sapiens
29 LRPPRC 10128
Proximity Label-MS Homo sapiens
30 HEATR3 55027
Affinity Capture-MS Homo sapiens
31 MCU 90550
Proximity Label-MS Homo sapiens
32 CRYZ 1429
Proximity Label-MS Homo sapiens
33 TFAM 7019
Proximity Label-MS Homo sapiens
34 PMPCA 23203
Proximity Label-MS Homo sapiens
35 C8orf82  
Proximity Label-MS Homo sapiens
36 NR2F6  
Affinity Capture-MS Homo sapiens
37 Naa50  
Affinity Capture-MS Mus musculus
38 MRPS23 51649
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 MRPS5 64969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 HINT2 84681
Proximity Label-MS Homo sapiens
41 DUSP11  
Affinity Capture-MS Homo sapiens
42 MRPS24 64951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 ZNF460  
Affinity Capture-MS Homo sapiens
44 SLC25A12 8604
Proximity Label-MS Homo sapiens
45 ZFYVE1 53349
Affinity Capture-MS Homo sapiens
46 DDRGK1 65992
Affinity Capture-MS Homo sapiens
47 KLF15  
Affinity Capture-MS Homo sapiens
48 RPS9 6203
Affinity Capture-MS Homo sapiens
49 MKLN1  
Affinity Capture-MS Homo sapiens
50 MRPS26 64949
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 SURF1  
Proximity Label-MS Homo sapiens
52 SRSF3 6428
Affinity Capture-MS Homo sapiens
53 DYNLL1 8655
Affinity Capture-MS Homo sapiens
54 EXD2  
Proximity Label-MS Homo sapiens
55 RC3H1 149041
Affinity Capture-MS Homo sapiens
56 ERAL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 KLF4  
Affinity Capture-MS Homo sapiens
58 E4F1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 MECP2 4204
Affinity Capture-MS Homo sapiens
61 PMPCB 9512
Proximity Label-MS Homo sapiens
62 RBM42  
Affinity Capture-MS Homo sapiens
63 FASTKD2  
Proximity Label-MS Homo sapiens
64 MTIF2 4528
Proximity Label-MS Homo sapiens
65 AMOT  
Affinity Capture-MS Homo sapiens
66 FAM120A 23196
Affinity Capture-MS Homo sapiens
67 MTERF3  
Proximity Label-MS Homo sapiens
68 MDH2 4191
Proximity Label-MS Homo sapiens
69 KLF16  
Affinity Capture-MS Homo sapiens
70 ACTA2 59
Co-fractionation Homo sapiens
71 MRPS25 64432
Affinity Capture-MS Homo sapiens
72 TPD52 7163
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 C6orf203  
Proximity Label-MS Homo sapiens
74 ZNF133  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 COX15 1355
Proximity Label-MS Homo sapiens
76 FASTKD5  
Proximity Label-MS Homo sapiens
77 WDR70 55100
Affinity Capture-MS Homo sapiens
78 PARK2  
Affinity Capture-MS Homo sapiens
79 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 MTO1  
Affinity Capture-MS Homo sapiens
81 ACSF3 197322
Affinity Capture-MS Homo sapiens
82 ZBTB47  
Affinity Capture-MS Homo sapiens
83 ARMC8 25852
Affinity Capture-MS Homo sapiens
84 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 YBX2 51087
Affinity Capture-MS Homo sapiens
86 MGME1  
Affinity Capture-MS Homo sapiens
87 YPEL5 51646
Affinity Capture-MS Homo sapiens
88 CPS1 1373
Affinity Capture-MS Homo sapiens
89 TUFM 7284
Proximity Label-MS Homo sapiens
90 ZBTB48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 DIABLO 56616
Proximity Label-MS Homo sapiens
92 PTCD3 55037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
93 HSCB 150274
Proximity Label-MS Homo sapiens
94 TBC1D32 221322
Proximity Label-MS Homo sapiens
95 GID8 54994
Affinity Capture-MS Homo sapiens
96 NTRK1 4914
Affinity Capture-MS Homo sapiens
97 MRPS6  
Affinity Capture-MS Homo sapiens
98 CCDC109B 55013
Proximity Label-MS Homo sapiens
99 TARS2 80222
Affinity Capture-MS Homo sapiens
100 CRAT 1384
Affinity Capture-MS Homo sapiens
101 TBRG4 9238
Proximity Label-MS Homo sapiens
102 GLI4  
Affinity Capture-MS Homo sapiens
103 KIAA0391  
Affinity Capture-MS Homo sapiens
104 RSAD1  
Affinity Capture-MS Homo sapiens
105 NARS2  
Affinity Capture-MS Homo sapiens
106 NOA1  
Affinity Capture-MS Homo sapiens
107 MTFMT  
Proximity Label-MS Homo sapiens
108 MRPL11 65003
Proximity Label-MS Homo sapiens
109 MTRF1L  
Proximity Label-MS Homo sapiens
110 LYPLA1 10434
Affinity Capture-MS Homo sapiens
111 HSD17B8  
Affinity Capture-MS Homo sapiens
112 MRPS14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 MRPS33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 GLTSCR2  
Affinity Capture-MS Homo sapiens
115 MRPL2 51069
Affinity Capture-MS Homo sapiens
116 COX4I1 1327
Proximity Label-MS Homo sapiens
117 PRKRIR  
Affinity Capture-MS Homo sapiens
118 OTC 5009
Proximity Label-MS Homo sapiens
119 LARS2 23395
Affinity Capture-MS Homo sapiens
120 MRRF  
Proximity Label-MS Homo sapiens
121 ABT1 29777
Affinity Capture-MS Homo sapiens
122 MRPS12  
Proximity Label-MS Homo sapiens
123 AURKAIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 DAP3 7818
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 MRPS35 60488
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
126 RC3H2  
Affinity Capture-MS Homo sapiens
127 YBX1 4904
Affinity Capture-MS Homo sapiens
128 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 MTIF3  
Proximity Label-MS Homo sapiens
130 SRSF5 6430
Affinity Capture-MS Homo sapiens
131 Nrip3  
Affinity Capture-MS Mus musculus
132 CUL3 8452
Affinity Capture-MS Homo sapiens
133 NR3C1 2908
Proximity Label-MS Homo sapiens
134 RMND1 55005
Proximity Label-MS Homo sapiens
135 EGFR 1956
Negative Genetic Homo sapiens
136 ELAC2 60528
Affinity Capture-MS Homo sapiens
137 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
138 DHX30 22907
Proximity Label-MS Homo sapiens
139 POLRMT 5442
Affinity Capture-MS Homo sapiens
140 MRPS28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 CECR5 27440
Affinity Capture-MS Homo sapiens
142 C12orf65  
Proximity Label-MS Homo sapiens
143 MYCN  
Affinity Capture-MS Homo sapiens
144 CEP250 11190
Affinity Capture-MS Homo sapiens
145 CYP24A1  
Affinity Capture-MS Homo sapiens
146 PCBP1 5093
Affinity Capture-MS Homo sapiens
147 TACO1  
Proximity Label-MS Homo sapiens
148 MTG1  
Proximity Label-MS Homo sapiens
149 MYC  
Affinity Capture-MS Homo sapiens
150 BAG1 573
Affinity Capture-MS Homo sapiens
151 TSFM 10102
Proximity Label-MS Homo sapiens
152 ACAD9 28976
Proximity Label-MS Homo sapiens
153 VWA8 23078
Proximity Label-MS Homo sapiens
154 CLPB 81570
Proximity Label-MS Homo sapiens
155 MRPS17 51373
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 Mad2l1 56150
Affinity Capture-MS Mus musculus
157 NSUN4  
Affinity Capture-MS Homo sapiens
158 LMNA 4000
Proximity Label-MS Homo sapiens
159 METTL15  
Proximity Label-MS Homo sapiens
160 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 SARDH 1757
Affinity Capture-MS Homo sapiens
162 MCUR1 63933
Proximity Label-MS Homo sapiens
163 RBMS2 5939
Affinity Capture-MS Homo sapiens
164 SOX2  
Affinity Capture-MS Homo sapiens
165 ZNF574  
Affinity Capture-MS Homo sapiens
166 APP 351
Reconstituted Complex Homo sapiens
167 CLPP 8192
Proximity Label-MS Homo sapiens
168 DNAJC28  
Proximity Label-MS Homo sapiens
169 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
170 ZNF707  
Affinity Capture-MS Homo sapiens
171 C8orf33 65265
Affinity Capture-MS Homo sapiens
172 C17orf80 55028
Proximity Label-MS Homo sapiens
173 ESR2  
Affinity Capture-MS Homo sapiens
174 METTL17  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 AUH 549
Proximity Label-MS Homo sapiens
176 POLG  
Affinity Capture-MS Homo sapiens
177 DNAJC19 131118
Proximity Label-MS Homo sapiens
178 MCAT 27349
Affinity Capture-MS Homo sapiens
179 TP53 7157
Affinity Capture-MS Homo sapiens
180 RPL6 6128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 PRR3  
Affinity Capture-MS Homo sapiens
182 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
183 Fbl 14113
Affinity Capture-MS Mus musculus
184 ZNF746  
Affinity Capture-MS Homo sapiens
185 MRPS18C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 MRPS31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 CUL5 8065
Affinity Capture-MS Homo sapiens
188 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
189 PPOX 5498
Affinity Capture-MS Homo sapiens
190 MRPS15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 COX8A  
Proximity Label-MS Homo sapiens
192 MRPS10 55173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 TMLHE 55217
Affinity Capture-MS Homo sapiens
194 C21orf33  
Proximity Label-MS Homo sapiens
195 MRPS21  
Affinity Capture-MS Homo sapiens
196 SSBP1 6742
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
197 Prpf3 70767
Affinity Capture-MS Mus musculus
198 TMEM70  
Proximity Label-MS Homo sapiens
199 UFL1 23376
Affinity Capture-MS Homo sapiens
200 FASTKD3  
Proximity Label-MS Homo sapiens
201 GID4  
Affinity Capture-MS Homo sapiens
202 LONP1 9361
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 MRPS18B 28973
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
204 GFM1 85476
Proximity Label-MS Homo sapiens
205 TEFM  
Proximity Label-MS Homo sapiens
206 MRPS9 64965
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
207 C19orf52  
Proximity Label-MS Homo sapiens
208 SLC25A51  
Proximity Label-MS Homo sapiens
209 RPUSD3  
Proximity Label-MS Homo sapiens
210 TRMT10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 MRPS16  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
212 GRSF1 2926
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
213 C1QBP 708
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
214 CUL7 9820
Affinity Capture-MS Homo sapiens
215 KRAS 3845
Negative Genetic Homo sapiens
216 HNRNPU 3192
Affinity Capture-MS Homo sapiens