Gene description for RANBP10
Gene name RAN binding protein 10
Gene symbol RANBP10
Other names/aliases -
Species Homo sapiens
 Database cross references - RANBP10
ExoCarta ExoCarta_57610
Vesiclepedia VP_57610
Entrez Gene 57610
HGNC 29285
MIM 614031
UniProt Q6VN20  
 RANBP10 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for RANBP10
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cytoskeleton organization GO:0007010 IBA
Subcellular Localization
    ubiquitin ligase complex GO:0000151 IDA
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified RANBP10 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RANBP10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 BRDT  
Affinity Capture-MS Homo sapiens
3 PRKCD 5580
Affinity Capture-Western Homo sapiens
4 PTX3 5806
Affinity Capture-MS Homo sapiens
5 GID4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 WDR26 80232
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
7 WBP5  
Affinity Capture-MS Homo sapiens
8 IL17F  
Affinity Capture-MS Homo sapiens
9 LECT2  
Affinity Capture-MS Homo sapiens
10 NEDD4L 23327
Biochemical Activity Homo sapiens
11 MRPS24 64951
Affinity Capture-MS Homo sapiens
12 GCG  
Affinity Capture-MS Homo sapiens
13 FTSJ2 29960
Affinity Capture-MS Homo sapiens
14 SYT2  
Affinity Capture-MS Homo sapiens
15 MKLN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 DRD1  
Affinity Capture-Western Homo sapiens
17 TULP3 7289
Affinity Capture-MS Homo sapiens
18 TCEB3B  
Affinity Capture-MS Homo sapiens
19 MRPL39 54148
Affinity Capture-MS Homo sapiens
20 HTRA2 27429
Affinity Capture-MS Homo sapiens
21 GDF15 9518
Affinity Capture-MS Homo sapiens
22 MRPL4 51073
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 NEDD4 4734
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
24 KCTD6  
Affinity Capture-MS Homo sapiens
25 DDX21 9188
Affinity Capture-MS Homo sapiens
26 ARMC8 25852
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 YPEL5 51646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 CHRDL2 25884
Affinity Capture-MS Homo sapiens
29 PRKCG 5582
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
30 Ypel5  
Affinity Capture-MS Mus musculus
31 CNTNAP4 85445
Two-hybrid Homo sapiens
32 GID8 54994
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 HAUS8  
Affinity Capture-MS Homo sapiens
34 RAN 5901
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
35 TIGD5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 EMILIN3  
Affinity Capture-MS Homo sapiens
37 TDGF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 WNT10A  
Affinity Capture-MS Homo sapiens
39 ADAMTS1 9510
Affinity Capture-MS Homo sapiens
40 INSL6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 RMND5A 64795
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 CT45A5  
Affinity Capture-MS Homo sapiens
43 GPS2  
Affinity Capture-MS Homo sapiens
44 KDF1  
Affinity Capture-MS Homo sapiens
45 CTAG1A  
Two-hybrid Homo sapiens
46 LY6H  
Affinity Capture-MS Homo sapiens
47 HLA-DPB1 3115
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 MMP7 4316
Affinity Capture-MS Homo sapiens
49 CBFA2T3  
Affinity Capture-MS Homo sapiens
50 PRG3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 PIGT 51604
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 JPH4 84502
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 MAGEA11  
Two-hybrid Homo sapiens
54 LILRB4  
Affinity Capture-MS Homo sapiens
55 IGSF1  
Two-hybrid Homo sapiens
56 CCDC120  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 THSD7B  
Two-hybrid Homo sapiens
58 CST8  
Affinity Capture-MS Homo sapiens
59 PRG2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 COQ4  
Affinity Capture-MS Homo sapiens
61 CUL3 8452
Affinity Capture-MS Homo sapiens
62 PSMA2 5683
Affinity Capture-MS Homo sapiens
63 SPON1 10418
Affinity Capture-MS Homo sapiens
64 IKZF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 MMP13  
Affinity Capture-MS Homo sapiens
66 RANBP9 10048
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 CORO2A  
Affinity Capture-MS Homo sapiens
68 GNLY  
Affinity Capture-MS Homo sapiens
69 MET 4233
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
70 BMP1 649
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 MRPL38  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 MRPL18 29074
Affinity Capture-MS Homo sapiens
73 PTPN14 5784
Affinity Capture-MS Homo sapiens
74 PRICKLE3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 DDX50 79009
Affinity Capture-MS Homo sapiens
76 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
77 EFHC2  
Affinity Capture-MS Homo sapiens
78 MRPS2 51116
Affinity Capture-MS Homo sapiens
79 NMB  
Affinity Capture-MS Homo sapiens
80 CTAG1B  
Two-hybrid Homo sapiens
81 PLCD3 113026
Affinity Capture-MS Homo sapiens
82 RMND5B  
Affinity Capture-MS Homo sapiens
83 CCDC106  
Affinity Capture-MS Homo sapiens
84 LARGE 9215
Affinity Capture-MS Homo sapiens
85 MEGF10 84466
Two-hybrid Homo sapiens
86 UFL1 23376
Affinity Capture-MS Homo sapiens
87 RAB8A 4218
Affinity Capture-MS Homo sapiens
88 EIF4B 1975
Affinity Capture-MS Homo sapiens
89 GLIPR1L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 GDNF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 IGFBP6 3489
Two-hybrid Homo sapiens
92 PRMT1 3276
Affinity Capture-MS Homo sapiens
93 NDUFS6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 NOTCH1 4851
Affinity Capture-MS Homo sapiens
95 CUL4A 8451
Affinity Capture-MS Homo sapiens
96 MAEA 10296
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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