Gene description for CHRDL2
Gene name chordin-like 2
Gene symbol CHRDL2
Other names/aliases BNF1
Species Homo sapiens
 Database cross references - CHRDL2
ExoCarta ExoCarta_25884
Entrez Gene 25884
HGNC 24168
MIM 613127
UniProt Q6WN34  
 CHRDL2 identified in exosomes derived from the following tissue/cell type
Breast milk 17641064    
 Gene ontology annotations for CHRDL2
Biological Process
    ossification GO:0001503 IEA
    cartilage development GO:0051216 IEA
    negative regulation of BMP signaling pathway GO:0030514 IEA
    cell differentiation GO:0030154 IEA
Subcellular Localization
    extracellular space GO:0005615 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified CHRDL2 in exosomes
Experiment ID 48
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Mature milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for CHRDL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 INHBA 3624
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which CHRDL2 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here