Gene description for PRKCD
Gene name protein kinase C, delta
Gene symbol PRKCD
Other names/aliases ALPS3
CVID9
MAY1
PKCD
nPKC-delta
Species Homo sapiens
 Database cross references - PRKCD
ExoCarta ExoCarta_5580
Vesiclepedia VP_5580
Entrez Gene 5580
HGNC 9399
MIM 176977
UniProt Q05655  
 PRKCD identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Urine 19056867    
 Gene ontology annotations for PRKCD
Molecular Function
    protein kinase activity GO:0004672 IDA
    protein serine/threonine kinase activity GO:0004674 IBA
    protein serine/threonine kinase activity GO:0004674 IDA
    diacylglycerol-dependent serine/threonine kinase activity GO:0004697 EXP
    diacylglycerol-dependent serine/threonine kinase activity GO:0004697 TAS
    calcium,diacylglycerol-dependent serine/threonine kinase activity GO:0004698 IEA
    diacylglycerol-dependent, calcium-independent serine/threonine kinase activity GO:0004699 ISS
    diacylglycerol-dependent, calcium-independent serine/threonine kinase activity GO:0004699 TAS
    non-membrane spanning protein tyrosine kinase activity GO:0004715 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    enzyme activator activity GO:0008047 IDA
    enzyme binding GO:0019899 IDA
    enzyme binding GO:0019899 IPI
    protein kinase binding GO:0019901 IPI
    histone H3Y41 kinase activity GO:0035401 IEA
    insulin receptor substrate binding GO:0043560 ISS
    metal ion binding GO:0046872 IEA
    protein serine kinase activity GO:0106310 IDA
    histone H2AXY142 kinase activity GO:0140801 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    protein phosphorylation GO:0006468 IDA
    apoptotic process GO:0006915 IDA
    DNA damage response GO:0006974 IMP
    signal transduction GO:0007165 TAS
    intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 TAS
    immunoglobulin mediated immune response GO:0016064 IEA
    peptidyl-serine phosphorylation GO:0018105 IDA
    peptidyl-threonine phosphorylation GO:0018107 IDA
    termination of signal transduction GO:0023021 IMP
    negative regulation of actin filament polymerization GO:0030837 ISS
    positive regulation of endodeoxyribonuclease activity GO:0032079 IMP
    activation of protein kinase activity GO:0032147 IDA
    positive regulation of superoxide anion generation GO:0032930 IMP
    regulation of actin cytoskeleton organization GO:0032956 IMP
    negative regulation of glial cell apoptotic process GO:0034351 IMP
    cellular response to UV GO:0034644 IDA
    intracellular signal transduction GO:0035556 IBA
    Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096 TAS
    B cell proliferation GO:0042100 IEA
    neutrophil activation GO:0042119 IDA
    positive regulation of protein import into nucleus GO:0042307 IMP
    defense response to bacterium GO:0042742 ISS
    negative regulation of MAPK cascade GO:0043409 IMP
    regulation of mRNA stability GO:0043488 TAS
    post-translational protein modification GO:0043687 IDA
    negative regulation of insulin receptor signaling pathway GO:0046627 ISS
    negative regulation of inflammatory response GO:0050728 IC
    negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 ISS
    protein stabilization GO:0050821 NAS
    negative regulation of filopodium assembly GO:0051490 ISS
    cell chemotaxis GO:0060326 IMP
    cellular response to hydrogen peroxide GO:0070301 IDA
    cellular response to fatty acid GO:0071398 TAS
    cellular response to hydroperoxide GO:0071447 IDA
    negative regulation of platelet aggregation GO:0090331 ISS
    cellular senescence GO:0090398 IMP
    positive regulation of phospholipid scramblase activity GO:1900163 IMP
    cellular response to angiotensin GO:1904385 IDA
    regulation of ceramide biosynthetic process GO:2000303 IDA
    positive regulation of ceramide biosynthetic process GO:2000304 IMP
    positive regulation of glucosylceramide catabolic process GO:2000753 IMP
    positive regulation of sphingomyelin catabolic process GO:2000755 IMP
    positive regulation of apoptotic signaling pathway GO:2001235 IEA
Subcellular Localization
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 IEA
    endoplasmic reticulum GO:0005783 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    cell-cell junction GO:0005911 IEA
    nuclear matrix GO:0016363 IEA
    azurophil granule lumen GO:0035578 TAS
    endolysosome GO:0036019 IDA
    perinuclear region of cytoplasm GO:0048471 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified PRKCD in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for PRKCD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNA12 2768
Biochemical Activity Homo sapiens
2 MTCH1 23787
Proximity Label-MS Homo sapiens
3 MED17  
Affinity Capture-MS Homo sapiens
4 SHC1 6464
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
5 POT1  
Affinity Capture-MS Homo sapiens
6 PRKCD 5580
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
7 FAM192A  
Affinity Capture-MS Homo sapiens
8 SP1  
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
9 RPL37A 6168
Affinity Capture-MS Homo sapiens
10 LAMP2 3920
Proximity Label-MS Homo sapiens
11 VHL  
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
12 BUD13  
Affinity Capture-MS Homo sapiens
13 NCF1  
Biochemical Activity Homo sapiens
14 SOX2  
Affinity Capture-MS Homo sapiens
15 APP 351
Reconstituted Complex Homo sapiens
16 GSK3A 2931
Biochemical Activity Homo sapiens
17 IL6ST 3572
Affinity Capture-Western Homo sapiens
18 GABRA1  
Affinity Capture-Western Homo sapiens
19 AFAP1 60312
Reconstituted Complex Homo sapiens
20 INSRR 3645
Affinity Capture-MS Homo sapiens
21 Nedd4 25489
Biochemical Activity Rattus norvegicus
22 RANBP10 57610
Affinity Capture-Western Homo sapiens
23 ADAM9 8754
Affinity Capture-Western Homo sapiens
24 HARS2 23438
Co-fractionation Homo sapiens
25 MUC1 4582
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
26 STAT3 6774
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
27 YWHAG 7532
Affinity Capture-Western Homo sapiens
28 TRO  
Affinity Capture-Western Homo sapiens
29 TIAM1  
Biochemical Activity Homo sapiens
30 TOM1L1 10040
Co-fractionation Homo sapiens
31 PLD2 5338
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
32 ATG7 10533
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
33 KLF4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
34 PPRC1  
Affinity Capture-MS Homo sapiens
35 PLS3 5358
Co-fractionation Homo sapiens
36 RASGRP3  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
37 FAS 355
Proximity Label-MS Homo sapiens
38 MAPK1 5594
Co-fractionation Homo sapiens
39 IL32  
Affinity Capture-Western Homo sapiens
40 TRIM41 90933
Affinity Capture-Western Homo sapiens
41 FOXC1  
Affinity Capture-MS Homo sapiens
42 IRAK1  
Affinity Capture-Western Homo sapiens
43 PARK2  
Affinity Capture-MS Homo sapiens
44 BEX4  
Affinity Capture-MS Homo sapiens
45 DARS 1615
Co-fractionation Homo sapiens
46 DIABLO 56616
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
47 FYN 2534
Co-localization Homo sapiens
48 PIK3CB 5291
Affinity Capture-Western Homo sapiens
49 PTK2B 2185
Affinity Capture-Western Homo sapiens
50 PDP2  
Affinity Capture-Western Homo sapiens
51 ZNF131  
Affinity Capture-MS Homo sapiens
52 PPP2CA 5515
Biochemical Activity Homo sapiens
53 TRAPPC13 80006
Affinity Capture-MS Homo sapiens
54 MALT1 10892
Affinity Capture-Western Homo sapiens
55 GNA13 10672
Biochemical Activity Homo sapiens
56 ITGB2 3689
Biochemical Activity Homo sapiens
57 HDAC5 10014
Biochemical Activity Homo sapiens
58 SEC61B 10952
Proximity Label-MS Homo sapiens
59 EBI3 10148
Affinity Capture-MS Homo sapiens
60 CHD9 80205
Affinity Capture-MS Homo sapiens
61 VCP 7415
Reconstituted Complex Homo sapiens
62 FLI1  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
63 PTOV1  
Biochemical Activity Homo sapiens
64 PRKCQ 5588
Affinity Capture-MS Homo sapiens
65 ZBTB2 57621
Affinity Capture-MS Homo sapiens
66 IBTK 25998
Affinity Capture-Western Homo sapiens
67 PRPF4B 8899
Affinity Capture-MS Homo sapiens
68 GRM5  
Co-localization Homo sapiens
69 PTPN6 5777
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
70 LAMP1 3916
Proximity Label-MS Homo sapiens
71 TNFRSF1A 7132
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
72 TRAF6 7189
Affinity Capture-Western Homo sapiens
73 ACTBL2 345651
Affinity Capture-MS Homo sapiens
74 YWHAZ 7534
Affinity Capture-Western Homo sapiens
75 CARD11  
Affinity Capture-Western Homo sapiens
76 LYSMD2  
Affinity Capture-MS Homo sapiens
77 PDPK1 5170
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
78 RIPK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
79 RANBP9 10048
Affinity Capture-Western Homo sapiens
80 KCNE3  
Affinity Capture-MS Homo sapiens
81 STAT1 6772
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
82 MYC  
Synthetic Lethality Homo sapiens
83 ATP2A1 487
Proximity Label-MS Homo sapiens
84 MTOR 2475
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
85 HSPA4 3308
Reconstituted Complex Homo sapiens
86 HIST1H1A 3024
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
87 RHOB 388
Proximity Label-MS Homo sapiens
88 H2BFS  
Affinity Capture-MS Homo sapiens
89 INPP5D 3635
Affinity Capture-Western Homo sapiens
90 PDP1 54704
Affinity Capture-Western Homo sapiens
91 CHUK 1147
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
92 AKAP1 8165
Proximity Label-MS Homo sapiens
93 SNCA 6622
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
94 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
95 ART3  
Reconstituted Complex Homo sapiens
96 SPRY2 10253
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
97 TP53 7157
Affinity Capture-Western Homo sapiens
98 MACF1 23499
Reconstituted Complex Homo sapiens
99 OPALIN  
Affinity Capture-MS Homo sapiens
100 Marcks 17118
Biochemical Activity Mus musculus
101 FXR1 8087
Affinity Capture-MS Homo sapiens
102 MEN1 4221
Affinity Capture-MS Homo sapiens
103 NGEF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 SQSTM1 8878
Affinity Capture-Western Homo sapiens
105 INSR 3643
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
106 HSPB1 3315
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
107 ELAVL1 1994
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
108 TKT 7086
Affinity Capture-MS Homo sapiens
109 HSP90AA1 3320
Reconstituted Complex Homo sapiens
110 ERGIC1 57222
Proximity Label-MS Homo sapiens
111 HIST1H1B 3009
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
112 CWC15  
Affinity Capture-MS Homo sapiens
113 PLSCR3 57048
Biochemical Activity Homo sapiens
114 DYNC1H1 1778
Reconstituted Complex Homo sapiens
115 TLR9  
Affinity Capture-MS Homo sapiens
116 IDE 3416
Co-fractionation Homo sapiens
117 DHX16 8449
Affinity Capture-MS Homo sapiens
118 NRAS 4893
Co-fractionation Homo sapiens
119 SEC62 7095
Proximity Label-MS Homo sapiens
120 PYGB 5834
Co-fractionation Homo sapiens
121 ITPR1 3708
Reconstituted Complex Homo sapiens
122 C1QBP 708
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
123 SERBP1 26135
Affinity Capture-MS Homo sapiens
124 PTGES3 10728
Co-fractionation Homo sapiens
125 PRKCB 5579
Affinity Capture-MS Homo sapiens
126 DUX3  
Affinity Capture-MS Homo sapiens
127 IKBKB 3551
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
128 IRS1 3667
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
129 NOTCH1 4851
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
130 EP300 2033
Biochemical Activity Homo sapiens
View the network image/svg+xml
 Pathways in which PRKCD is involved
PathwayEvidenceSource
Apoptosis TAS Reactome
Apoptotic cleavage of cellular proteins TAS Reactome
Apoptotic execution phase TAS Reactome
C-type lectin receptors (CLRs) TAS Reactome
Ca-dependent events TAS Reactome
Calmodulin induced events TAS Reactome
CaM pathway TAS Reactome
Cellular response to chemical stress IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
CLEC7A (Dectin-1) signaling TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
DAG and IP3 signaling TAS Reactome
Effects of PIP2 hydrolysis TAS Reactome
Fcgamma receptor (FCGR) dependent phagocytosis TAS Reactome
G alpha (i) signalling events TAS Reactome
G alpha (q) signalling events TAS Reactome
G alpha (z) signalling events IEA Reactome
G-protein mediated events TAS Reactome
GPCR downstream signalling TAS Reactome
GPCR downstream signalling IEA Reactome
Hemostasis TAS Reactome
HuR (ELAVL1) binds and stabilizes mRNA TAS Reactome
Immune System TAS Reactome
Innate Immune System TAS Reactome
Interferon gamma signaling TAS Reactome
Interferon Signaling TAS Reactome
Intracellular signaling by second messengers TAS Reactome
KEAP1-NFE2L2 pathway IEA Reactome
Metabolism of RNA TAS Reactome
Neutrophil degranulation TAS Reactome
Opioid Signalling TAS Reactome
Platelet activation, signaling and aggregation TAS Reactome
PLC beta mediated events TAS Reactome
Programmed Cell Death TAS Reactome
Regulation of mRNA stability by proteins that bind AU-rich elements TAS Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases Activate NADPH Oxidases TAS Reactome
Role of phospholipids in phagocytosis TAS Reactome
SHC1 events in ERBB2 signaling TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by ERBB2 TAS Reactome
Signaling by GPCR TAS Reactome
Signaling by GPCR IEA Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by VEGF TAS Reactome
VEGFA-VEGFR2 Pathway TAS Reactome
VEGFR2 mediated cell proliferation TAS Reactome





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