Gene description for TRIM41
Gene name
tripartite motif containing 41
Gene symbol
TRIM41
Other names/aliases
RINCK
Species
Homo sapiens
Database cross references - TRIM41
ExoCarta
ExoCarta_90933
Entrez Gene
90933
HGNC
19013
MIM
610530
UniProt
Q8WV44
TRIM41 identified in exosomes derived from the following tissue/cell type
Hepatocytes
26054723
Mesenchymal stem cells
Unpublished / Not applicable
Gene ontology annotations for TRIM41
Experiment description of studies that identified TRIM41 in exosomes
1
Experiment ID
237
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
2
Experiment ID
126
ISEV standards
✘
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
Protein-protein interactions for TRIM41
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ZNF263
Two-hybrid
Homo sapiens
2
ZBTB8
Two-hybrid
Homo sapiens
3
ZNF473
25888
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which TRIM41 is involved
No pathways found