Gene description for TRIM41
Gene name tripartite motif containing 41
Gene symbol TRIM41
Other names/aliases RINCK
Species Homo sapiens
 Database cross references - TRIM41
ExoCarta ExoCarta_90933
Vesiclepedia VP_90933
Entrez Gene 90933
HGNC 19013
MIM 610530
UniProt Q8WV44  
 TRIM41 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for TRIM41
Molecular Function
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    identical protein binding GO:0042802 IPI
    ubiquitin protein ligase activity GO:0061630 IBA
    ubiquitin protein ligase activity GO:0061630 IDA
Biological Process
    protein monoubiquitination GO:0006513 IDA
    innate immune response GO:0045087 IBA
    defense response to virus GO:0051607 IDA
    positive regulation of type I interferon-mediated signaling pathway GO:0060340 IDA
    cellular response to lipopolysaccharide GO:0071222 IMP
    cellular response to muramyl dipeptide GO:0071225 IMP
Subcellular Localization
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IEA
    nuclear body GO:0016604 IBA
    nuclear body GO:0016604 IDA
 Experiment description of studies that identified TRIM41 in exosomes
1
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
2
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for TRIM41
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRAIP  
Two-hybrid Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 ZBTB38 253461
Two-hybrid Homo sapiens
4 MCRS1  
Two-hybrid Homo sapiens
5 ZNF74  
Affinity Capture-MS Homo sapiens
6 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
7 ZNF24  
Two-hybrid Homo sapiens
8 PRKCD 5580
Affinity Capture-Western Homo sapiens
9 ZNF286A  
Two-hybrid Homo sapiens
10 ZNF552  
Two-hybrid Homo sapiens
11 SYCE1  
Two-hybrid Homo sapiens
12 KIFC3 3801
Two-hybrid Homo sapiens
13 SRPK2 6733
Biochemical Activity Homo sapiens
14 AES 166
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
15 TRIM26 7726
Two-hybrid Homo sapiens
16 RPL13A 23521
Affinity Capture-MS Homo sapiens
17 HIST1H2BG 8339
Affinity Capture-MS Homo sapiens
18 MAGEA1  
Affinity Capture-Western Homo sapiens
19 ZSCAN16  
Two-hybrid Homo sapiens
20 BYSL 705
Two-hybrid Homo sapiens
21 PSMG4  
Affinity Capture-MS Homo sapiens
22 GAS8  
Two-hybrid Homo sapiens
23 CSNK2A1 1457
Two-hybrid Homo sapiens
24 TRIM55  
Two-hybrid Homo sapiens
25 ZNF439  
Two-hybrid Homo sapiens
26 ZNF398  
Two-hybrid Homo sapiens
27 SERPINA3 12
Affinity Capture-MS Homo sapiens
28 ANKRD28 23243
Proximity Label-MS Homo sapiens
29 STX11 8676
Two-hybrid Homo sapiens
30 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
31 KLK7 5650
Affinity Capture-MS Homo sapiens
32 PBX4  
Two-hybrid Homo sapiens
33 GPATCH2L  
Two-hybrid Homo sapiens
34 ZNF121  
Two-hybrid Homo sapiens
35 RNPS1 10921
Two-hybrid Homo sapiens
36 ZNF266  
Two-hybrid Homo sapiens
37 ZNF408  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
38 LRRC1 55227
Affinity Capture-MS Homo sapiens
39 Nedd4 25489
Reconstituted Complex Rattus norvegicus
40 FRA10AC1 118924
Two-hybrid Homo sapiens
41 ALPK2  
Affinity Capture-MS Homo sapiens
42 SUV39H1  
Two-hybrid Homo sapiens
43 ZSCAN21  
Two-hybrid Homo sapiens
44 ZNF2  
Two-hybrid Homo sapiens
45 DMD 1756
Affinity Capture-MS Homo sapiens
46 Cenpe  
Affinity Capture-MS Mus musculus
47 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
48 PHF11 51131
Two-hybrid Homo sapiens
49 ZNF219  
Two-hybrid Homo sapiens
50 PHF7  
Two-hybrid Homo sapiens
51 SYTL4 94121
Two-hybrid Homo sapiens
52 ZNF165  
Two-hybrid Homo sapiens
53 AKTIP  
Two-hybrid Homo sapiens
54 PPP3R1 5534
Affinity Capture-MS Homo sapiens
55 ZNF780A  
Two-hybrid Homo sapiens
56 TRIM4 89122
Two-hybrid Homo sapiens
57 KIF14 9928
Affinity Capture-MS Homo sapiens
58 CTSV 1515
Affinity Capture-MS Homo sapiens
59 TBC1D26  
Two-hybrid Homo sapiens
60 ZNF562  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 AEN  
Two-hybrid Homo sapiens
62 ZNF134 7693
Two-hybrid Homo sapiens
63 TRIM41 90933
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
64 ZNF550  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 AQP1 358
Two-hybrid Homo sapiens
66 ZNF26  
Two-hybrid Homo sapiens
67 ZFP1  
Two-hybrid Homo sapiens
68 GGPS1  
Affinity Capture-MS Homo sapiens
69 TOP3B 8940
Two-hybrid Homo sapiens
70 SRP14 6727
Affinity Capture-MS Homo sapiens
71 ANKRD17 26057
Affinity Capture-MS Homo sapiens
72 ZNF526  
Two-hybrid Homo sapiens
73 CST6  
Affinity Capture-MS Homo sapiens
74 TARBP2  
Affinity Capture-MS Homo sapiens
75 KLHL9 55958
Affinity Capture-MS Homo sapiens
76 SBSN 374897
Affinity Capture-MS Homo sapiens
77 TCEA2  
Two-hybrid Homo sapiens
78 ZFP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
79 ZNF417  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
80 ZBTB48  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
81 UBE2I 7329
Two-hybrid Homo sapiens
82 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
83 ANKHD1 54882
Affinity Capture-MS Homo sapiens
84 FAM124A  
Two-hybrid Homo sapiens
85 JRK  
Two-hybrid Homo sapiens
86 ZNF837  
Two-hybrid Homo sapiens
87 BPIFB1 92747
Affinity Capture-MS Homo sapiens
88 ZSCAN26  
Two-hybrid Homo sapiens
89 ZNF655  
Two-hybrid Homo sapiens
90 MEOX2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
91 ZNF784  
Two-hybrid Homo sapiens
92 ZNF251  
Two-hybrid Homo sapiens
93 TRIM17  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
94 BRAP  
Two-hybrid Homo sapiens
95 FAM9A  
Two-hybrid Homo sapiens
96 C3orf49  
Affinity Capture-MS Homo sapiens
97 PRPF31 26121
Two-hybrid Homo sapiens
98 MAGEH1  
Two-hybrid Homo sapiens
99 TRIM63  
Two-hybrid Homo sapiens
100 ZNF773  
Two-hybrid Homo sapiens
101 DDAH2 23564
Affinity Capture-MS Homo sapiens
102 ZNF319  
Two-hybrid Homo sapiens
103 EPB41L1 2036
Affinity Capture-MS Homo sapiens
104 KATNBL1  
Two-hybrid Homo sapiens
105 ZNF473 25888
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
106 ABT1 29777
Affinity Capture-MS Homo sapiens
107 PRKCA 5578
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
108 AHCYL1 10768
Affinity Capture-MS Homo sapiens
109 RPL15 6138
Affinity Capture-MS Homo sapiens
110 ZBTB24  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
111 ERBB2IP 55914
Affinity Capture-MS Homo sapiens
112 KRTAP10-8  
Two-hybrid Homo sapiens
113 ZNF564  
Two-hybrid Homo sapiens
114 PIP5K1P1  
Affinity Capture-MS Homo sapiens
115 PRKCZ 5590
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
116 ZNF71  
Two-hybrid Homo sapiens
117 CUL3 8452
Affinity Capture-MS Homo sapiens
118 HIST3H2BB 128312
Affinity Capture-MS Homo sapiens
119 ZNF835  
Two-hybrid Homo sapiens
120 ZNF250  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
121 FARP2 9855
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 PKD1 5310
Affinity Capture-Western Homo sapiens
123 DCAF16 54876
Affinity Capture-MS Homo sapiens
124 MORF4L1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
125 ZNF223  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 ZNF670  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
127 ZCCHC7  
Two-hybrid Homo sapiens
128 COL1A1 1277
Affinity Capture-MS Homo sapiens
129 DVL3 1857
Two-hybrid Homo sapiens
130 PUS7L  
Two-hybrid Homo sapiens
131 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
132 UBE2D2 7322
Reconstituted Complex Homo sapiens
133 AGO4  
Affinity Capture-MS Homo sapiens
134 HSP90AA4P 3323
Affinity Capture-MS Homo sapiens
135 DICER1  
Affinity Capture-MS Homo sapiens
136 CCNL2 81669
Two-hybrid Homo sapiens
137 MFAP1  
Two-hybrid Homo sapiens
138 ZBTB39  
Two-hybrid Homo sapiens
139 HIST1H2BA 255626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 CSNK2A2 1459
Two-hybrid Homo sapiens
141 ZNF785  
Affinity Capture-MS Homo sapiens
142 ZNF653  
Two-hybrid Homo sapiens
143 SORBS3 10174
Two-hybrid Homo sapiens
144 ZNF587  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
145 RNF2  
Affinity Capture-MS Homo sapiens
146 TCEANC  
Two-hybrid Homo sapiens
147 ANKRD23 200539
Two-hybrid Homo sapiens
148 ZNF696  
Two-hybrid Homo sapiens
149 ZNF497  
Two-hybrid Homo sapiens
150 HIST1H2BI 8346
Affinity Capture-MS Homo sapiens
151 PASK  
Affinity Capture-MS Homo sapiens
152 NEDD4L 23327
Reconstituted Complex Homo sapiens
153 ZNF263  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 ZNF329  
Two-hybrid Homo sapiens
155 ZNF575  
Two-hybrid Homo sapiens
156 ZNF574  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 GFM2 84340
Affinity Capture-MS Homo sapiens
158 PIP5K1A 8394
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 ZNF669  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 KIAA0232 9778
Affinity Capture-MS Homo sapiens
161 C8orf33 65265
Two-hybrid Homo sapiens
162 DEPTOR 64798
Two-hybrid Homo sapiens
163 SERPINA12  
Affinity Capture-MS Homo sapiens
164 ANKHD1-EIF4EBP3  
Affinity Capture-MS Homo sapiens
165 PRDM14  
Two-hybrid Homo sapiens
166 PLAGL2  
Two-hybrid Homo sapiens
167 ZNF264  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 ZBTB8A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
169 TRIM52  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
170 CXorf67  
Two-hybrid Homo sapiens
171 EHHADH 1962
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
172 ZNF169 169841
Affinity Capture-MS Homo sapiens
173 IKBKG 8517
Reconstituted Complex Homo sapiens
174 ZFP64  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
175 ZBTB26  
Two-hybrid Homo sapiens
176 ZNF48  
Two-hybrid Homo sapiens
177 MORF4L2  
Two-hybrid Homo sapiens
178 BIVM  
Two-hybrid Homo sapiens
179 RBAK  
Two-hybrid Homo sapiens
180 ZNF764 92595
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
182 ZNF490  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
183 ZNF460  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
184 ZNF648  
Two-hybrid Homo sapiens
185 CHD2 1106
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
186 ZNF792 126375
Two-hybrid Homo sapiens
187 NCK2 8440
Two-hybrid Homo sapiens
188 CTSH 1512
Affinity Capture-MS Homo sapiens
189 CEP44  
Two-hybrid Homo sapiens
190 ZNF691  
Two-hybrid Homo sapiens
191 HIST2H2AA4 723790
Affinity Capture-MS Homo sapiens
192 ZNF138  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
193 QRICH1  
Affinity Capture-MS Homo sapiens
194 FAM161A  
Two-hybrid Homo sapiens
195 TRIM31  
Affinity Capture-MS Homo sapiens
196 APBA2 321
Affinity Capture-MS Homo sapiens
197 GLCCI1 113263
Affinity Capture-MS Homo sapiens
198 ZNF629 23361
Two-hybrid Homo sapiens
199 PHC2  
Two-hybrid Homo sapiens
200 RPL36AL 6166
Affinity Capture-MS Homo sapiens
201 PRKCB 5579
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
202 ALS2CR12  
Two-hybrid Homo sapiens
203 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
204 TNNI1 7135
Two-hybrid Homo sapiens
205 MOBP  
Two-hybrid Homo sapiens
206 KRTAP10-9  
Two-hybrid Homo sapiens
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