Gene description for TRIM41
Gene name tripartite motif containing 41
Gene symbol TRIM41
Other names/aliases RINCK
Species Homo sapiens
 Database cross references - TRIM41
ExoCarta ExoCarta_90933
Entrez Gene 90933
HGNC 19013
MIM 610530
UniProt Q8WV44  
 TRIM41 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for TRIM41
Molecular Function
    ligase activity GO:0016874 IEA
    zinc ion binding GO:0008270 IEA
    protein binding GO:0005515 IPI
Biological Process
    protein ubiquitination GO:0016567 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified TRIM41 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
2
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for TRIM41
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF263  
Two-hybrid Homo sapiens
2 ZBTB8  
Two-hybrid Homo sapiens
3 ZNF473 25888
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which TRIM41 is involved
No pathways found





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