Gene description for ZBTB38
Gene name zinc finger and BTB domain containing 38
Gene symbol ZBTB38
Other names/aliases CIBZ
PPP1R171
ZNF921
Species Homo sapiens
 Database cross references - ZBTB38
ExoCarta ExoCarta_253461
Entrez Gene 253461
HGNC 26636
MIM 612218
UniProt Q8NAP3  
 ZBTB38 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for ZBTB38
Molecular Function
    protein homodimerization activity GO:0042803 IDA
    metal ion binding GO:0046872 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 ISS
    protein binding GO:0005515 IPI
    methyl-CpG binding GO:0008327 IDA
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISS
    negative regulation of transcription, DNA-templated GO:0045892 IDA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleus GO:0005634 ISS
    blood microparticle GO:0072562 IDA
 Experiment description of studies that identified ZBTB38 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for ZBTB38
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZBTB38 is involved
No pathways found





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