Experiment description of studies that identified FSD2 in exosomes

1 Experiment ID 234 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-C3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for FSD2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ZBTB38 253461 Two-hybrid Homo sapiens 2 MCRS1   Two-hybrid Homo sapiens 3 ENKD1   Two-hybrid Homo sapiens 4 MAP7D1 55700 Affinity Capture-MS Homo sapiens 5 ATXN7L2   Two-hybrid Homo sapiens 6 AES 166 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 7 FMR1 2332 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 8 OXNAD1 92106 Two-hybrid Homo sapiens 9 TTC23   Two-hybrid Homo sapiens 10 MID1 4281 Affinity Capture-MS Homo sapiens 11 PBX3   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 12 ZMAT2   Two-hybrid Homo sapiens 13 ZNF648   Two-hybrid Homo sapiens 14 ZNF230   Two-hybrid Homo sapiens 15 ZNF408   Two-hybrid Homo sapiens 16 GLG1 2734 Affinity Capture-MS Homo sapiens 17 PPP2R5D 5528 Two-hybrid Homo sapiens 18 RNF8   Two-hybrid Homo sapiens 19 LENG1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 20 PPP1R18 170954 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 21 POLL   Two-hybrid Homo sapiens 22 HGS 9146 Two-hybrid Homo sapiens 23 CCDC112   Two-hybrid Homo sapiens 24 OIP5   Two-hybrid Homo sapiens 25 ZNF20   Two-hybrid Homo sapiens 26 ZNF35   Two-hybrid Homo sapiens 27 MGC50722   Two-hybrid Homo sapiens 28 RCOR3   Two-hybrid Homo sapiens 29 KCTD6   Affinity Capture-MS Homo sapiens 30 EXOC3 11336 Two-hybrid Homo sapiens 31 IFT20 90410 Two-hybrid Homo sapiens 32 C1orf216   Two-hybrid Homo sapiens 33 KANSL1   Two-hybrid Homo sapiens 34 ZYX 7791 Affinity Capture-MS Homo sapiens 35 SPAG5 10615 Affinity Capture-MS Homo sapiens 36 FARS2 10667 Two-hybrid Homo sapiens 37 AQP1 358 Two-hybrid Homo sapiens 38 VEZF1   Two-hybrid Homo sapiens 39 TSGA10IP   Two-hybrid Homo sapiens 40 BEX2   Two-hybrid Homo sapiens 41 ZNF124   Two-hybrid Homo sapiens 42 PSMB4 5692 Two-hybrid Homo sapiens 43 FAM110A   Two-hybrid Homo sapiens 44 SCNM1   Two-hybrid Homo sapiens 45 PNMA5 114824 Two-hybrid Homo sapiens 46 FAM107A   Two-hybrid Homo sapiens 47 DTNB 1838 Two-hybrid Homo sapiens 48 SLC27A4 10999 Affinity Capture-MS Homo sapiens 49 ZNF837   Two-hybrid Homo sapiens 50 ZNF572   Two-hybrid Homo sapiens 51 ZNF580   Two-hybrid Homo sapiens 52 TACC1 6867 Affinity Capture-MS Homo sapiens 53 PRPF18   Two-hybrid Homo sapiens 54 ZNF581   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 55 MRPL11 65003 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 56 PRPF31 26121 Two-hybrid Homo sapiens 57 CTAG1A   Two-hybrid Homo sapiens 58 MAP7 9053 Affinity Capture-MS Homo sapiens 59 CDC73   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 60 CBX8 57332 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 61 FAM50B   Two-hybrid Homo sapiens 62 LETM1 3954 Affinity Capture-MS Homo sapiens 63 CCDC120   Two-hybrid Homo sapiens 64 NGFRAP1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 65 ASPM 259266 Affinity Capture-MS Homo sapiens 66 BRD8 10902 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 67 ZNF324   Affinity Capture-MS Homo sapiens 68 IFFO1   Affinity Capture-MS Homo sapiens 69 ZNF835   Two-hybrid Homo sapiens 70 ZSCAN26   Two-hybrid Homo sapiens 71 FAM90A1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 72 ATG14   Two-hybrid Homo sapiens 73 ZNF777   Two-hybrid Homo sapiens 74 BIRC6 57448 Affinity Capture-MS Homo sapiens 75 ESD 2098 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 76 ZNF410   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 77 CORO1A 11151 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 78 ZNF587   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 79 TCEANC   Two-hybrid Homo sapiens 80 ZC2HC1C   Two-hybrid Homo sapiens 81 ATF7IP2 80063 Two-hybrid Homo sapiens 82 ZNF417   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 83 CCHCR1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 84 RPP25L   Affinity Capture-MS Homo sapiens 85 CCDC146   Two-hybrid Homo sapiens 86 CTAG1B   Two-hybrid Homo sapiens 87 JUN 3725 Affinity Capture-MS Homo sapiens 88 CDK18 5129 Two-hybrid Homo sapiens 89 CWF19L2   Two-hybrid Homo sapiens 90 SNAPIN 23557 Two-hybrid Homo sapiens 91 ZNF490   Two-hybrid Homo sapiens 92 KLHL40   Two-hybrid Homo sapiens 93 ARFIP2 23647 Two-hybrid Homo sapiens 94 MKI67   Affinity Capture-MS Homo sapiens 95 LATS1   Two-hybrid Homo sapiens 96 THAP7   Two-hybrid Homo sapiens 97 ABI2 10152 Affinity Capture-MS Homo sapiens 98 UBTFL1   Two-hybrid Homo sapiens 99 FAM161A   Two-hybrid Homo sapiens 100 SPATC1L   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 101 SH2D4A 63898 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 102 ZNF774   Two-hybrid Homo sapiens 103 NDN 4692 Two-hybrid Homo sapiens 104 PIK3R3 8503 Two-hybrid Homo sapiens View the network

Pathways in which FSD2 is involved

No pathways found