Experiment description of studies that identified ASPM in sEVs

1 Experiment ID 226 MISEV standards ✔ EM Biophysical techniques ✔ GAPDH|CD9|FLOT1 Enriched markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 Negative markers ✘ Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

Protein-protein interactions for ASPM

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CENPB 1059 Affinity Capture-MS Homo sapiens 2 DNAJB8 165721 Affinity Capture-MS Homo sapiens 3 LIG4 3981 Two-hybrid Homo sapiens 4 PRKAA1 5562 Affinity Capture-MS Homo sapiens 5 IARS2 55699 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 TEX13A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 CNKSR1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 IPO7 10527 Affinity Capture-MS Homo sapiens 9 FOXJ1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 MOAP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 PHLPP1   Proximity Label-MS Homo sapiens 12 TRIM66   Affinity Capture-MS Homo sapiens 13 ACTC1 70 Proximity Label-MS Homo sapiens 14 LIMS1 3987 Affinity Capture-MS Homo sapiens 15 Ndc80   Affinity Capture-MS Mus musculus 16 UBE3A 7337 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 17 CALM1 801 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 DNAJB6 10049 Proximity Label-MS Homo sapiens 19 LRPPRC 10128 Cross-Linking-MS (XL-MS) Homo sapiens 20 HSPA4 3308 Affinity Capture-MS Homo sapiens 21 CDC16 8881 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 CRYZ 1429 Affinity Capture-MS Homo sapiens 23 ATP1A3 478 Cross-Linking-MS (XL-MS) Homo sapiens 24 KIF23 9493 Affinity Capture-MS Homo sapiens 25 MXD3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 ZNF460   Affinity Capture-MS Homo sapiens 27 CALM3 808 Affinity Capture-MS Homo sapiens 28 MAGEA9   Affinity Capture-MS Homo sapiens 29 MID2 11043 Affinity Capture-MS Homo sapiens 30 MAP3K6   Affinity Capture-MS Homo sapiens 31 NAP1L4 4676 Affinity Capture-MS Homo sapiens 32 SNX7 51375 Affinity Capture-MS Homo sapiens 33 FSD2 123722 Affinity Capture-MS Homo sapiens 34 SSR3 6747 Affinity Capture-MS Homo sapiens 35 CRTAC1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 GNB5 10681 Negative Genetic Homo sapiens 37 CCDC83   Affinity Capture-MS Homo sapiens 38 KIF14 9928 Affinity Capture-MS Homo sapiens 39 RNF135   Negative Genetic Homo sapiens 40 CCDC114   Affinity Capture-MS Homo sapiens 41 GPN3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 TP53INP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 AURKA 6790 Affinity Capture-MS Homo sapiens 44 PPP1CA 5499 Reconstituted Complex Homo sapiens 45 SLC25A10 1468 Affinity Capture-MS Homo sapiens 46 TSGA10IP   Affinity Capture-MS Homo sapiens 47 TRAFD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 PPP6R2 9701 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 SDCCAG3   Affinity Capture-MS Homo sapiens 50 PTPRS 5802 Negative Genetic Homo sapiens 51 EIF2B5 8893 Affinity Capture-MS Homo sapiens 52 CSRNP1   Affinity Capture-MS Homo sapiens 53 DNAJB7   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 RSPH6A   Affinity Capture-MS Homo sapiens 55 DTNBP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 56 TUBA1B 10376 Affinity Capture-MS Homo sapiens 57 CDH5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 ZNF333   Affinity Capture-MS Homo sapiens 59 IFI16 3428 Affinity Capture-MS Homo sapiens 60 PNMA2   Affinity Capture-MS Homo sapiens 61 CREB3   Affinity Capture-MS Homo sapiens 62 STIL   Proximity Label-MS Homo sapiens 63 HECTD1 25831 Affinity Capture-MS Homo sapiens 64 COPS7B 64708 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 DNAJB5   Proximity Label-MS Homo sapiens 66 HAUS7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 PIPSL 266971 Affinity Capture-MS Homo sapiens 68 STK32C   Affinity Capture-MS Homo sapiens 69 INTS4P2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 70 ANLN 54443 Affinity Capture-MS Homo sapiens 71 DKK3 27122 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 NUMA1 4926 Affinity Capture-MS Homo sapiens 73 PER2   Affinity Capture-MS Homo sapiens 74 PSMA3 5684 Affinity Capture-MS Homo sapiens 75 TUBGCP5 114791 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 76 Prkcz   Affinity Capture-MS Mus musculus 77 ECT2 1894 Affinity Capture-MS Homo sapiens 78 NCAPH2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 79 PSMD8 5714 Co-fractionation Homo sapiens 80 CTNNB1 1499 Affinity Capture-MS Homo sapiens 81 ANO3   Affinity Capture-MS Homo sapiens 82 SPC24 147841 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 83 CUL3 8452 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 84 NAP1L1 4673 Affinity Capture-MS Homo sapiens 85 TP73   Affinity Capture-Western Homo sapiens 86 RCN1 5954 Affinity Capture-MS Homo sapiens 87 GPRASP2   Affinity Capture-MS Homo sapiens 88 PACS2 23241 Affinity Capture-MS Homo sapiens 89 LZTS2 84445 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 90 INPP5K 51763 Negative Genetic Homo sapiens 91 MAPK6   Affinity Capture-MS Homo sapiens 92 RRAS 6237 Negative Genetic Homo sapiens 93 SET 6418 Cross-Linking-MS (XL-MS) Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 94 MTOR 2475 Affinity Capture-MS Homo sapiens 95 TP63   Affinity Capture-Western Homo sapiens 96 FAM46A   Affinity Capture-MS Homo sapiens 97 NDC80 10403 Proximity Label-MS Homo sapiens 98 PSMC5 5705 Affinity Capture-MS Homo sapiens 99 RCN2 5955 Affinity Capture-MS Homo sapiens 100 NEUROG3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 101 PMS2P3   Affinity Capture-MS Homo sapiens 102 FTL 2512 Affinity Capture-MS Homo sapiens 103 FEZ1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 104 FASN 2194 Negative Genetic Homo sapiens 105 TP53 7157 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 106 MAPK8IP2   Affinity Capture-MS Homo sapiens 107 PEX19 5824 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 108 TRIM52   Affinity Capture-MS Homo sapiens 109 CALU 813 Affinity Capture-MS Homo sapiens 110 ELL   Affinity Capture-MS Homo sapiens 111 CPPED1 55313 Negative Genetic Homo sapiens 112 OS9 10956 Affinity Capture-MS Homo sapiens 113 MYL2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 114 THAP7   Affinity Capture-MS Homo sapiens 115 SKAP1 8631 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 116 CALM2 805 Affinity Capture-MS Homo sapiens 117 KRT38 8687 Affinity Capture-MS Homo sapiens 118 HLA-DPA1   Affinity Capture-MS Homo sapiens 119 CDK4 1019 Affinity Capture-MS Homo sapiens 120 EAF1   Affinity Capture-MS Homo sapiens 121 ZCCHC10   Affinity Capture-MS Homo sapiens 122 CEP78 84131 Affinity Capture-MS Homo sapiens 123 EID1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 124 KRAS 3845 Synthetic Lethality Homo sapiens 125 RPP38 10557 Affinity Capture-MS Homo sapiens 126 LURAP1   Affinity Capture-MS Homo sapiens 127 INTU   Affinity Capture-MS Homo sapiens View the network

Pathways in which ASPM is involved

No pathways found