Gene description for MTUS2
Gene name microtubule associated tumor suppressor candidate 2
Gene symbol MTUS2
Other names/aliases CAZIP
ICIS
KIAA0774
TIP150
Species Homo sapiens
 Database cross references - MTUS2
ExoCarta ExoCarta_23281
Vesiclepedia VP_23281
Entrez Gene 23281
HGNC 20595
UniProt Q5JR59  
 MTUS2 identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for MTUS2
Molecular Function
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 IBA
    microtubule binding GO:0008017 IDA
    protein homodimerization activity GO:0042803 IPI
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IBA
    centrosome GO:0005813 IDA
    cytoplasmic microtubule GO:0005881 IDA
    microtubule cytoskeleton GO:0015630 IDA
    intercellular bridge GO:0045171 IDA
 Experiment description of studies that identified MTUS2 in exosomes
1
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MTUS2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LINC00636  
Two-hybrid Homo sapiens
2 RALY 22913
Two-hybrid Homo sapiens
3 ZFP64  
Two-hybrid Homo sapiens
4 MLLT4 4301
Affinity Capture-MS Homo sapiens
5 PRKAA1 5562
Two-hybrid Homo sapiens
6 RAB3IL1 5866
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 HDAC4  
Two-hybrid Homo sapiens
8 C14orf105  
Two-hybrid Homo sapiens
9 POLDIP3 84271
Two-hybrid Homo sapiens
10 ZFP1  
Two-hybrid Homo sapiens
11 INO80B 83444
Two-hybrid Homo sapiens
12 NUDT10  
Two-hybrid Homo sapiens
13 SLIRP 81892
Two-hybrid Homo sapiens
14 CCDC116  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
15 KIFC3 3801
Two-hybrid Homo sapiens
16 PKP2 5318
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
17 RPS19BP1  
Two-hybrid Homo sapiens
18 AES 166
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
19 GTPBP10  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
20 MYO15B 80022
Two-hybrid Homo sapiens
21 CATSPER1  
Two-hybrid Homo sapiens
22 FASTKD5  
Two-hybrid Homo sapiens
23 FRA10AC1 118924
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 PLSCR4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
25 DHRS1 115817
Two-hybrid Homo sapiens
26 SMARCE1 6605
Two-hybrid Homo sapiens
27 BYSL 705
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
28 ENKD1  
Two-hybrid Homo sapiens
29 FAM13C  
Two-hybrid Homo sapiens
30 MYOM1  
Two-hybrid Homo sapiens
31 CYSLTR2  
Two-hybrid Homo sapiens
32 TTC23  
Two-hybrid Homo sapiens
33 COG2 22796
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
34 ZNF439  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
35 RASD1  
Two-hybrid Homo sapiens
36 ATP11C 286410
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 ZNF224  
Two-hybrid Homo sapiens
38 FBXO34  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
39 ZNF426  
Two-hybrid Homo sapiens
40 HAPLN2  
Two-hybrid Homo sapiens
41 SPG7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
42 ZNF3  
Two-hybrid Homo sapiens
43 ZMAT2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
44 PPP1R18 170954
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
45 LMO2  
Two-hybrid Homo sapiens
46 HOXB9  
Two-hybrid Homo sapiens
47 ZNF648  
Two-hybrid Homo sapiens
48 MOS 4342
Two-hybrid Homo sapiens
49 ZNF230  
Two-hybrid Homo sapiens
50 PRR35  
Two-hybrid Homo sapiens
51 SMG9 56006
Two-hybrid Homo sapiens
52 HCK 3055
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
53 C8orf34  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
54 ZNF408  
Two-hybrid Homo sapiens
55 DMRT3  
Two-hybrid Homo sapiens
56 VASN 114990
Two-hybrid Homo sapiens
57 AFF4 27125
Two-hybrid Homo sapiens
58 ABHD15  
Two-hybrid Homo sapiens
59 DCTN4 51164
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
60 PTPMT1 114971
Two-hybrid Homo sapiens
61 RASAL3 64926
Two-hybrid Homo sapiens
62 LENG1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
63 PLK4  
Two-hybrid Homo sapiens
64 FAM110A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
65 CD109 135228
Affinity Capture-MS Homo sapiens
66 ZNF512B  
Two-hybrid Homo sapiens
67 ENPP7 339221
Two-hybrid Homo sapiens
68 TULP2  
Two-hybrid Homo sapiens
69 EIF5B 9669
Affinity Capture-MS Homo sapiens
70 CTSZ 1522
Two-hybrid Homo sapiens
71 MTUS2 23281
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
72 CCDC6 8030
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 TCEA2  
Two-hybrid Homo sapiens
74 PTCD1 26024
Two-hybrid Homo sapiens
75 LRR1  
Two-hybrid Homo sapiens
76 GAL3ST2  
Two-hybrid Homo sapiens
77 ATP6V0D2 245972
Affinity Capture-MS Homo sapiens
78 ZNF20  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
79 PTK7 5754
Two-hybrid Homo sapiens
80 ICAM4  
Two-hybrid Homo sapiens
81 KIF2C 11004
Affinity Capture-Western Homo sapiens
82 SETD5 55209
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
83 CCDC115 84317
Affinity Capture-MS Homo sapiens
84 DDX6 1656
Two-hybrid Homo sapiens
85 MTDH 92140
Affinity Capture-MS Homo sapiens
86 CATIP  
Two-hybrid Homo sapiens
87 PLEKHN1  
Two-hybrid Homo sapiens
88 RANBP3L  
Two-hybrid Homo sapiens
89 USP2  
Two-hybrid Homo sapiens
90 ZFHX3  
Two-hybrid Homo sapiens
91 PSMA1 5682
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
92 SDCBP 6386
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
93 ARNT2  
Two-hybrid Homo sapiens
94 MRPL11 65003
Two-hybrid Homo sapiens
95 RCOR3  
Two-hybrid Homo sapiens
96 DLGAP5  
Two-hybrid Homo sapiens
97 ATP6AP1 537
Affinity Capture-MS Homo sapiens
98 LMO4  
Two-hybrid Homo sapiens
99 CDC20B  
Two-hybrid Homo sapiens
100 GAS2L2  
Two-hybrid Homo sapiens
101 C1orf216  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
102 CACNB3  
Two-hybrid Homo sapiens
103 IQCE 23288
Two-hybrid Homo sapiens
104 GTF2I 2969
Two-hybrid Homo sapiens
105 AEN  
Two-hybrid Homo sapiens
106 ZNF415  
Two-hybrid Homo sapiens
107 RHOA 387
Affinity Capture-MS Homo sapiens
108 AQP1 358
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
109 LIMS2 55679
Two-hybrid Homo sapiens
110 C19orf44  
Two-hybrid Homo sapiens
111 BEX2  
Two-hybrid Homo sapiens
112 ZNF124  
Two-hybrid Homo sapiens
113 RGS2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
114 FHL3 2275
Two-hybrid Homo sapiens
115 RPL9 6133
Two-hybrid Homo sapiens
116 SCEL 8796
Two-hybrid Homo sapiens
117 ROBO3  
Two-hybrid Homo sapiens
118 CDKN1A  
Two-hybrid Homo sapiens
119 CNNM3 26505
Two-hybrid Homo sapiens
120 ZBTB16  
Two-hybrid Homo sapiens
121 ZBTB47  
Two-hybrid Homo sapiens
122 MGC50722  
Two-hybrid Homo sapiens
123 TNFRSF10B 8795
Affinity Capture-MS Homo sapiens
124 TTLL10 254173
Two-hybrid Homo sapiens
125 ZFP2  
Two-hybrid Homo sapiens
126 TRIM42  
Two-hybrid Homo sapiens
127 SCNM1  
Two-hybrid Homo sapiens
128 MAPRE1 22919
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
129 ZNF844  
Two-hybrid Homo sapiens
130 CAST 831
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 ARL4A  
Two-hybrid Homo sapiens
132 FAM107A  
Two-hybrid Homo sapiens
133 PAG1 55824
Affinity Capture-MS Homo sapiens
134 GEM  
Two-hybrid Homo sapiens
135 RAP1B 5908
Two-hybrid Homo sapiens
136 NELFE 7936
Two-hybrid Homo sapiens
137 NDOR1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
138 WDYHV1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
139 DTNB 1838
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
140 ZNF23  
Two-hybrid Homo sapiens
141 ZNF837  
Two-hybrid Homo sapiens
142 GOLGA2P11  
Two-hybrid Homo sapiens
143 ZNF35  
Two-hybrid Homo sapiens
144 ZNF572  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
145 ZSCAN26  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
146 BMP7 655
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
147 POLDIP2 26073
Two-hybrid Homo sapiens
148 CDK5R1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
149 DCAF10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 PKN1 5585
Two-hybrid Homo sapiens
151 CRY2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
152 PRPF18  
Two-hybrid Homo sapiens
153 ZNF581  
Two-hybrid Homo sapiens
154 BANF2  
Two-hybrid Homo sapiens
155 ZFC3H1 196441
Two-hybrid Homo sapiens
156 FAM124B  
Two-hybrid Homo sapiens
157 UTP14C  
Two-hybrid Homo sapiens
158 ZNF564  
Two-hybrid Homo sapiens
159 PRPF31 26121
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
160 ZNF239  
Two-hybrid Homo sapiens
161 TEAD4  
Two-hybrid Homo sapiens
162 ZNF438  
Two-hybrid Homo sapiens
163 TAF13  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
164 SLC23A1 9963
Two-hybrid Homo sapiens
165 BARD1 580
Two-hybrid Homo sapiens
166 SNRPB2 6629
Two-hybrid Homo sapiens
167 TXN2 25828
Two-hybrid Homo sapiens
168 ZNF580  
Two-hybrid Homo sapiens
169 UBTFL1  
Two-hybrid Homo sapiens
170 SLC22A5 6584
Two-hybrid Homo sapiens
171 MYADM 91663
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 DDX46 9879
Affinity Capture-MS Homo sapiens
173 MYPOP  
Two-hybrid Homo sapiens
174 ACSM1 116285
Two-hybrid Homo sapiens
175 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
176 CDC73  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
177 PPAP2C 8612
Affinity Capture-MS Homo sapiens
178 CCDC185  
Two-hybrid Homo sapiens
179 CEP57L1  
Two-hybrid Homo sapiens
180 SPATC1L  
Two-hybrid Homo sapiens
181 ZNF232  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
182 HOXB5  
Two-hybrid Homo sapiens
183 CCDC120  
Two-hybrid Homo sapiens
184 TCHP  
Two-hybrid Homo sapiens
185 MTUS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 ZNF337  
Two-hybrid Homo sapiens
187 PRKAA2 5563
Two-hybrid Homo sapiens
188 KRT75 9119
Two-hybrid Homo sapiens
189 CEP95  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
190 C19orf66  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
191 CERK 64781
Two-hybrid Homo sapiens
192 ZSCAN12  
Two-hybrid Homo sapiens
193 SYT6  
Two-hybrid Homo sapiens
194 CCP110  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 MARK4  
Two-hybrid Homo sapiens
196 DOHH 83475
Affinity Capture-MS Homo sapiens
197 SLC25A48  
Two-hybrid Homo sapiens
198 ZNF250  
Two-hybrid Homo sapiens
199 ZNF557  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
200 GADD45GIP1  
Two-hybrid Homo sapiens
201 FAM90A1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
202 ANKRD11 29123
Two-hybrid Homo sapiens
203 MACF1 23499
Affinity Capture-MS Homo sapiens
204 SPATA8  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
205 IL16  
Two-hybrid Homo sapiens
206 TFG 10342
Affinity Capture-MS Homo sapiens
207 ZNF670  
Two-hybrid Homo sapiens
208 NXF1 10482
Two-hybrid Homo sapiens
209 SH3RF2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
210 PPHLN1  
Two-hybrid Homo sapiens
211 ZNF655  
Two-hybrid Homo sapiens
212 CXCL16 58191
Two-hybrid Homo sapiens
213 TACO1  
Two-hybrid Homo sapiens
214 MFAP1  
Two-hybrid Homo sapiens
215 PACSIN3 29763
Affinity Capture-MS Homo sapiens
216 LYSMD1  
Two-hybrid Homo sapiens
217 HDDC2 51020
Affinity Capture-MS Homo sapiens
218 TCEANC  
Two-hybrid Homo sapiens
219 FCHSD2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
220 FAM74A4  
Two-hybrid Homo sapiens
221 TSHZ3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
222 ZNF410  
Two-hybrid Homo sapiens
223 JMY  
Two-hybrid Homo sapiens
224 ZFYVE21  
Two-hybrid Homo sapiens
225 ITGB4 3691
Two-hybrid Homo sapiens
226 KAT5  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
227 RHPN1  
Two-hybrid Homo sapiens
228 TP53RK 112858
Two-hybrid Homo sapiens
229 RIBC2  
Two-hybrid Homo sapiens
230 ZNF587  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
231 METTL17  
Two-hybrid Homo sapiens
232 FYN 2534
Affinity Capture-MS Homo sapiens
233 ATP6V0A1 535
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens