Gene description for SETD5
Gene name SET domain containing 5
Gene symbol SETD5
Other names/aliases -
Species Homo sapiens
 Database cross references - SETD5
ExoCarta ExoCarta_55209
Vesiclepedia VP_55209
Entrez Gene 55209
HGNC 25566
MIM 615743
UniProt Q9C0A6  
 SETD5 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for SETD5
Molecular Function
    protein binding GO:0005515 IPI
 Experiment description of studies that identified SETD5 in exosomes
1
Experiment ID 234
MISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for SETD5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRAF2 7186
Two-hybrid Homo sapiens
2 DIPA  
Two-hybrid Homo sapiens
3 DPPA2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SETD5 is involved
No pathways found





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