Gene description for IQCE
Gene name IQ motif containing E
Gene symbol IQCE
Other names/aliases 1700028P05Rik
Species Homo sapiens
 Database cross references - IQCE
ExoCarta ExoCarta_23288
Vesiclepedia VP_23288
Entrez Gene 23288
HGNC 29171
UniProt Q6IPM2  
 IQCE identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for IQCE
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    limb morphogenesis GO:0035108 IMP
Subcellular Localization
    cilium GO:0005929 TAS
    ciliary membrane GO:0060170 IEA
 Experiment description of studies that identified IQCE in exosomes
1
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for IQCE
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PSMA3 5684
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 CALM2 805
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
3 CARD9 64170
Two-hybrid Homo sapiens
4 MGAT5B  
Two-hybrid Homo sapiens
5 CALM1 801
Two-hybrid Homo sapiens
6 RPGRIP1  
Two-hybrid Homo sapiens
7 MCC 4163
Affinity Capture-MS Homo sapiens
8 TTC23L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
9 TTC23  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
10 HOOK2  
Two-hybrid Homo sapiens
11 GPSM3  
Two-hybrid Homo sapiens
12 DDX58 23586
Affinity Capture-RNA Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
14 RFFL 117584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 PSMD14 10213
Affinity Capture-MS Homo sapiens
16 GOLGA2 2801
Two-hybrid Homo sapiens
17 Kat8  
Affinity Capture-MS Mus musculus
18 LZTS2 84445
Two-hybrid Homo sapiens
19 SPAG5 10615
Two-hybrid Homo sapiens
20 CEP70  
Two-hybrid Homo sapiens
21 TRIM23 373
Two-hybrid Homo sapiens
22 TRIM27  
Two-hybrid Homo sapiens
23 HNRNPF 3185
Two-hybrid Homo sapiens
24 CLEC11A 6320
Affinity Capture-MS Homo sapiens
25 CALM3 808
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
26 MTUS2 23281
Two-hybrid Homo sapiens
27 MYL12B 103910
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IQCE is involved
PathwayEvidenceSource
Activation of SMO TAS Reactome
Hedgehog 'on' state TAS Reactome
Signal Transduction TAS Reactome
Signaling by Hedgehog TAS Reactome





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