Gene description for SCEL
Gene name sciellin
Gene symbol SCEL
Other names/aliases -
Species Homo sapiens
 Database cross references - SCEL
ExoCarta ExoCarta_8796
Vesiclepedia VP_8796
Entrez Gene 8796
HGNC 10573
MIM 604112
UniProt O95171  
 SCEL identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SCEL
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    epidermis development GO:0008544 IBA
    epidermis development GO:0008544 ISS
    epidermis development GO:0008544 TAS
    response to mechanical stimulus GO:0009612 IEP
    embryo development ending in birth or egg hatching GO:0009792 ISS
    keratinocyte differentiation GO:0030216 IDA
    positive regulation of canonical Wnt signaling pathway GO:0090263 IMP
Subcellular Localization
    cornified envelope GO:0001533 TAS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISS
    perinuclear region of cytoplasm GO:0048471 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SCEL in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SCEL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FNDC5  
Affinity Capture-MS Homo sapiens
2 AGPAT1 10554
Affinity Capture-MS Homo sapiens
3 C18orf21  
Affinity Capture-MS Homo sapiens
4 PTPRD 5789
Reconstituted Complex Homo sapiens
5 NMI  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
6 KIFC3 3801
Two-hybrid Homo sapiens
7 TBC1D22B  
Affinity Capture-MS Homo sapiens
8 MTUS2 23281
Two-hybrid Homo sapiens
9 SOX2  
Affinity Capture-MS Homo sapiens
10 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
11 HSF2  
Affinity Capture-MS Homo sapiens
12 GOLGA2 2801
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
13 SRRT 51593
Affinity Capture-MS Homo sapiens
14 FRMD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 CDH1 999
Proximity Label-MS Homo sapiens
16 STK11 6794
Affinity Capture-MS Homo sapiens
17 FXR2 9513
Two-hybrid Homo sapiens
18 TXNIP 10628
Two-hybrid Homo sapiens
19 RAB11B 9230
Affinity Capture-MS Homo sapiens
20 BRD1 23774
Affinity Capture-MS Homo sapiens
21 SSUH2  
Affinity Capture-MS Homo sapiens
22 TSC22D2 9819
Two-hybrid Homo sapiens
23 OR2A4 79541
Affinity Capture-MS Homo sapiens
24 FAM213A 84293
Affinity Capture-MS Homo sapiens
25 CCR1  
Affinity Capture-MS Homo sapiens
26 STX17 55014
Affinity Capture-MS Homo sapiens
27 TSGA10  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SCEL is involved
No pathways found





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