Gene description for SCEL
Gene name sciellin
Gene symbol SCEL
Other names/aliases -
Species Homo sapiens
 Database cross references - SCEL
ExoCarta ExoCarta_8796
Entrez Gene 8796
HGNC 10573
MIM 604112
UniProt O95171  
 SCEL identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SCEL
Molecular Function
    zinc ion binding GO:0008270 IEA
    protein binding GO:0005515 IPI
Biological Process
    epidermis development GO:0008544 TAS
    embryo development GO:0009790 ISS
    keratinocyte differentiation GO:0030216 IDA
Subcellular Localization
    cornified envelope GO:0001533 TAS
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified SCEL in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SCEL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TXNIP  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SCEL is involved
No pathways found





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