Gene description for TSC22D2
Gene name TSC22 domain family, member 2
Gene symbol TSC22D2
Other names/aliases TILZ4a
TILZ4b
TILZ4c
Species Homo sapiens
 Database cross references - TSC22D2
ExoCarta ExoCarta_9819
Entrez Gene 9819
HGNC 29095
UniProt O75157  
 TSC22D2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for TSC22D2
Molecular Function
    sequence-specific DNA binding transcription factor activity GO:0003700 IEA
Biological Process
    response to osmotic stress GO:0006970 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
 Experiment description of studies that identified TSC22D2 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for TSC22D2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TSC22D2 is involved
No pathways found





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