Gene description for PRKAA2
Gene name	protein kinase, AMP-activated, alpha 2 catalytic subunit
Gene symbol	PRKAA2
Other names/aliases	AMPK AMPK2 AMPKa2 PRKAA
Species	Homo sapiens
Database cross references - PRKAA2
ExoCarta	ExoCarta_5563
Entrez Gene	5563
HGNC	9377
MIM	600497
UniProt	P54646
PRKAA2 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for PRKAA2

Molecular Function     protein serine/threonine/tyrosine kinase activity GO:0004712 IDA     metal ion binding GO:0046872 IEA     histone serine kinase activity GO:0035174 ISS     chromatin binding GO:0003682 ISS     AMP-activated protein kinase activity GO:0004679 IDA     protein serine/threonine kinase activity GO:0004674 ISS     [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity GO:0047322 IEA     ATP binding GO:0005524 IEA     [acetyl-CoA carboxylase] kinase activity GO:0050405 IEA     protein kinase activity GO:0004672 TAS     protein binding GO:0005515 IPI Biological Process     cell cycle arrest GO:0007050 TAS     negative regulation of TOR signaling GO:0032007 ISS     lipid biosynthetic process GO:0008610 ISS     rhythmic process GO:0048511 IEA     transcription initiation from RNA polymerase II promoter GO:0006367 TAS     small molecule metabolic process GO:0044281 TAS     membrane organization GO:0061024 TAS     regulation of transcription, DNA-templated GO:0006355 IEA     regulation of energy homeostasis GO:2000505 ISS     fatty acid homeostasis GO:0055089 ISS     positive regulation of glycolytic process GO:0045821 ISS     histone-serine phosphorylation GO:0035404 IBA     organelle organization GO:0006996 TAS     intracellular signal transduction GO:0035556 IBA     regulation of macroautophagy GO:0016241 ISS     protein phosphorylation GO:0006468 TAS     gene expression GO:0010467 TAS     fatty acid biosynthetic process GO:0006633 IEA     regulation of fatty acid biosynthetic process GO:0042304 TAS     cholesterol biosynthetic process GO:0006695 IEA     carnitine shuttle GO:0006853 TAS     glucose homeostasis GO:0042593 ISS     negative regulation of apoptotic process GO:0043066 ISS     cellular response to glucose starvation GO:0042149 ISS     cellular lipid metabolic process GO:0044255 TAS     positive regulation of autophagy GO:0010508 ISS     Wnt signaling pathway GO:0016055 IEA     cellular response to nutrient levels GO:0031669 ISS     response to stress GO:0006950 ISS     mitochondrion organization GO:0007005 TAS     regulation of circadian rhythm GO:0042752 ISS     signal transduction GO:0007165 TAS     energy reserve metabolic process GO:0006112 TAS     autophagy GO:0006914 IEA     insulin receptor signaling pathway GO:0008286 TAS Subcellular Localization     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IBA     AMP-activated protein kinase complex GO:0031588 IBA