Gene description for REL
Gene name	v-rel avian reticuloendotheliosis viral oncogene homolog
Gene symbol	REL
Other names/aliases	C-Rel
Species	Homo sapiens
Database cross references - REL
ExoCarta	ExoCarta_5966
Entrez Gene	5966
HGNC	9954
MIM	164910
UniProt	Q04864
REL identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for REL

Molecular Function     sequence-specific DNA binding transcription factor activity GO:0003700 NAS     chromatin binding GO:0003682 IBA     RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 IDA     RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0001205 IDA     protein binding GO:0005515 IPI Biological Process     I-kappaB kinase/NF-kappaB signaling GO:0007249 IBA     NIK/NF-kappaB signaling GO:0038061 IBA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA     negative regulation of interferon-beta production GO:0032688 IDA     innate immune response GO:0045087 IBA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IBA     negative regulation of neuron death GO:1901215 IEA     inflammatory response GO:0006954 IBA     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IEP     response to cytokine GO:0034097 IBA     negative regulation of gene expression GO:0010629 IDA     cytokine production GO:0001816 IEA     transcription, DNA-templated GO:0006351 IEA     positive regulation of interleukin-12 biosynthetic process GO:0045084 IEA Subcellular Localization     cytosol GO:0005829 TAS     I-kappaB/NF-kappaB complex GO:0033256 IBA     transcription factor complex GO:0005667 IEA     nucleoplasm GO:0005654 TAS     nucleus GO:0005634 IMP