Gene description for ATP6V0D2
Gene name ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
Gene symbol ATP6V0D2
Other names/aliases ATP6D2
VMA6
Species Homo sapiens
 Database cross references - ATP6V0D2
ExoCarta ExoCarta_245972
Vesiclepedia VP_245972
Entrez Gene 245972
HGNC 18266
UniProt Q8N8Y2  
 ATP6V0D2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for ATP6V0D2
Molecular Function
    hydrogen ion transmembrane transporter activity GO:0015078 IEA
    protein binding GO:0005515 IPI
Biological Process
    insulin receptor signaling pathway GO:0008286 TAS
    phagosome maturation GO:0090382 TAS
    transferrin transport GO:0033572 TAS
    ion transmembrane transport GO:0034220 TAS
    transmembrane transport GO:0055085 TAS
    cellular iron ion homeostasis GO:0006879 TAS
    interaction with host GO:0051701 TAS
    ATP hydrolysis coupled proton transport GO:0015991 IEA
Subcellular Localization
    phagocytic vesicle membrane GO:0030670 TAS
    membrane GO:0016020 IDA
    endosome membrane GO:0010008 TAS
    extracellular exosome GO:0070062 IDA
    proton-transporting V-type ATPase, V0 domain GO:0033179 IEA
    early endosome GO:0005769 IEA
    apical plasma membrane GO:0016324 IDA
    vacuolar proton-transporting V-type ATPase complex GO:0016471 IDA
 Experiment description of studies that identified ATP6V0D2 in exosomes
1
Experiment ID 63
MISEV standards
EV Biophysical techniques
AQP2
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ATP6V0D2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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