Gene description for ZNF134
Gene name zinc finger protein 134
Gene symbol ZNF134
Other names/aliases pHZ-15
Species Homo sapiens
 Database cross references - ZNF134
ExoCarta ExoCarta_7693
Vesiclepedia VP_7693
Entrez Gene 7693
HGNC 12918
MIM 604076
UniProt P52741  
 ZNF134 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ZNF134
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IBA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IBA
    regulation of cytokine production GO:0001817 IBA
    regulation of immune system process GO:0002682 IBA
Subcellular Localization
    nucleoplasm GO:0005654 IBA
 Experiment description of studies that identified ZNF134 in sEVs
1
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ZNF134
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TNS2 23371
Two-hybrid Homo sapiens
2 TRIM41 90933
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF134 is involved
No pathways found





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