Gene description for INPP5D
Gene name	inositol polyphosphate-5-phosphatase, 145kDa
Gene symbol	INPP5D
Other names/aliases	SHIP SHIP-1 SHIP1 SIP-145 hp51CN p150Ship
Species	Homo sapiens
Database cross references - INPP5D
ExoCarta	ExoCarta_3635
Entrez Gene	3635
HGNC	6079
MIM	601582
UniProt	Q92835
INPP5D identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for INPP5D

Molecular Function     PTB domain binding GO:0051425 IEA     inositol-polyphosphate 5-phosphatase activity GO:0004445 IEA     SH3 domain binding GO:0017124 IEA     phosphatidylinositol trisphosphate phosphatase activity GO:0034594 IEA     protein binding GO:0005515 IPI Biological Process     positive regulation of B cell differentiation GO:0045579 IEA     determination of adult lifespan GO:0008340 IEA     negative regulation of osteoclast differentiation GO:0045671 IEA     phosphatidylinositol dephosphorylation GO:0046856 IEA     phosphatidylinositol biosynthetic process GO:0006661 TAS     blood coagulation GO:0007596 TAS     immunoglobulin mediated immune response GO:0016064 IEA     negative regulation of bone resorption GO:0045779 IEA     negative regulation of monocyte differentiation GO:0045656 IEA     apoptotic process GO:0006915 IEA     phospholipid metabolic process GO:0006644 TAS     positive regulation of apoptotic process GO:0043065 IEA     negative regulation of immune response GO:0050777 IEA     intracellular signal transduction GO:0035556 IEA     negative regulation of neutrophil differentiation GO:0045659 IEA     negative regulation of signal transduction GO:0009968 IEA     negative regulation of interleukin-6 biosynthetic process GO:0045409 IEA     phosphate-containing compound metabolic process GO:0006796 TAS     leukocyte migration GO:0050900 TAS     positive regulation of erythrocyte differentiation GO:0045648 IEA     signal transduction GO:0007165 TAS     negative regulation of B cell proliferation GO:0030889 IEA     small molecule metabolic process GO:0044281 TAS     inositol phosphate metabolic process GO:0043647 TAS     T cell receptor signaling pathway GO:0050852 TAS Subcellular Localization     cytosol GO:0005829 TAS     membrane GO:0016020 IEA