Gene description for ITGB2
Gene name	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Gene symbol	ITGB2
Other names/aliases	CD18 LAD LCAMB LFA-1 MAC-1 MF17 MFI7
Species	Homo sapiens
Database cross references - ITGB2
ExoCarta	ExoCarta_3689
Entrez Gene	3689
HGNC	6155
MIM	600065
UniProt	P05107
ITGB2 identified in exosomes derived from the following tissue/cell type
B cells	20458337
B cells	20458337
B cells	20458337
Platelets	25332113
Platelets	25332113
Platelets	25332113
T cells	11907077
Thymus	23844026

Gene ontology annotations for ITGB2

Molecular Function     protein kinase binding GO:0019901 IPI     cell adhesion molecule binding GO:0050839 IMP     glycoprotein binding GO:0001948 IPI     metal ion binding GO:0046872 IEA     ICAM-3 receptor activity GO:0030369 IMP     protein heterodimerization activity GO:0046982 IEA     protein binding GO:0005515 IPI     protein complex binding GO:0032403 IEA Biological Process     integrin-mediated signaling pathway GO:0007229 NAS     positive regulation of angiogenesis GO:0045766 IEA     innate immune response GO:0045087 TAS     apoptotic process GO:0006915 NAS     regulation of cell shape GO:0008360 NAS     leukocyte migration GO:0050900 TAS     cell-cell signaling GO:0007267 NAS     neutrophil chemotaxis GO:0030593 IDA     regulation of immune response GO:0050776 TAS     inflammatory response GO:0006954 NAS     cell adhesion GO:0007155 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 IEA     activated T cell proliferation GO:0050798 IEA     blood coagulation GO:0007596 TAS     regulation of peptidyl-tyrosine phosphorylation GO:0050730 IDA     aging GO:0007568 IEA     toll-like receptor signaling pathway GO:0002224 TAS     cell-matrix adhesion GO:0007160 IMP     extracellular matrix organization GO:0030198 TAS     heterotypic cell-cell adhesion GO:0034113 IMP     endodermal cell differentiation GO:0035987 IEP     natural killer cell activation GO:0030101 IEA     toll-like receptor 4 signaling pathway GO:0034142 TAS     leukocyte migration involved in inflammatory response GO:0002523 IEA     leukocyte cell-cell adhesion GO:0007159 IDA     receptor clustering GO:0043113 IMP     cellular extravasation GO:0045123 IEA     positive regulation of nitric oxide biosynthetic process GO:0045429 IEA     endothelial cell migration GO:0043542 IEA Subcellular Localization     membrane GO:0016020 IDA     plasma membrane GO:0005886 TAS     receptor complex GO:0043235 IDA     extracellular vesicle GO:1903561 IDA     cell surface GO:0009986 IDA     extracellular exosome GO:0070062 IDA     integrin alphaL-beta2 complex GO:0034687 IDA     integrin complex GO:0008305 NAS     membrane raft GO:0045121 IEA