Gene description for MRPS22
Gene name mitochondrial ribosomal protein S22
Gene symbol MRPS22
Other names/aliases C3orf5
COXPD5
GIBT
GK002
MRP-S22
RPMS22
Species Homo sapiens
 Database cross references - MRPS22
ExoCarta ExoCarta_56945
Entrez Gene 56945
HGNC 14508
MIM 605810
UniProt P82650  
 MRPS22 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for MRPS22
Molecular Function
    structural constituent of ribosome GO:0003735 IDA
Biological Process
    mitochondrial translational termination GO:0070126 TAS
    organelle organization GO:0006996 TAS
    mitochondrial translation GO:0032543 TAS
    biological_process GO:0008150 ND
    mitochondrial translational initiation GO:0070124 TAS
    mitochondrial translational elongation GO:0070125 TAS
Subcellular Localization
    mitochondrion GO:0005739 IDA
    mitochondrial ribosome GO:0005761 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 IDA
 Experiment description of studies that identified MRPS22 in exosomes
1
Experiment ID 191
ISEV standards
✘ EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MRPS22
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NFKBIL1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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