Gene description for MRPS25
Gene name mitochondrial ribosomal protein S25
Gene symbol MRPS25
Other names/aliases MRP-S25
RPMS25
Species Homo sapiens
 Database cross references - MRPS25
ExoCarta ExoCarta_64432
Vesiclepedia VP_64432
Entrez Gene 64432
HGNC 14511
MIM 611987
UniProt P82663  
 MRPS25 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPS25
Molecular Function
    structural constituent of ribosome GO:0003735 IBA
Biological Process
    mitochondrial translation GO:0032543 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 NAS
 Experiment description of studies that identified MRPS25 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPS25
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 CDC14B 8555
Affinity Capture-MS Homo sapiens
4 PDHA1 5160
Proximity Label-MS Homo sapiens
5 MRPS27 23107
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 UBE2H 7328
Affinity Capture-MS Homo sapiens
7 SLIRP 81892
Proximity Label-MS Homo sapiens
8 MCM8 84515
Affinity Capture-MS Homo sapiens
9 H1FNT  
Affinity Capture-MS Homo sapiens
10 GTPBP8  
Affinity Capture-MS Homo sapiens
11 MRPL17  
Affinity Capture-MS Homo sapiens
12 ZNF668  
Affinity Capture-MS Homo sapiens
13 TMEM135  
Cross-Linking-MS (XL-MS) Homo sapiens
14 MME 4311
Affinity Capture-MS Homo sapiens
15 RPL13A 23521
Affinity Capture-MS Homo sapiens
16 TRUB2  
Proximity Label-MS Homo sapiens
17 EPB41L5 57669
Affinity Capture-MS Homo sapiens
18 MTG2  
Proximity Label-MS Homo sapiens
19 NGRN  
Proximity Label-MS Homo sapiens
20 RPL10 6134
Affinity Capture-MS Homo sapiens
21 CHCHD1  
Proximity Label-MS Homo sapiens
22 CAND1 55832
Affinity Capture-MS Homo sapiens
23 RPUSD4 84881
Proximity Label-MS Homo sapiens
24 DNAJC15  
Proximity Label-MS Homo sapiens
25 MTRF1  
Proximity Label-MS Homo sapiens
26 GFM2 84340
Proximity Label-MS Homo sapiens
27 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
28 CCDC90B  
Proximity Label-MS Homo sapiens
29 LRPPRC 10128
Proximity Label-MS Homo sapiens
30 COPS5 10987
Affinity Capture-MS Homo sapiens
31 Med22  
Affinity Capture-MS Mus musculus
32 KBTBD6  
Affinity Capture-MS Homo sapiens
33 HNRNPAB 3182
Co-fractionation Homo sapiens
34 ZBTB2 57621
Affinity Capture-MS Homo sapiens
35 MCU 90550
Proximity Label-MS Homo sapiens
36 CRYZ 1429
Proximity Label-MS Homo sapiens
37 TFAM 7019
Proximity Label-MS Homo sapiens
38 PMPCA 23203
Proximity Label-MS Homo sapiens
39 C8orf82  
Proximity Label-MS Homo sapiens
40 MRPL23 6150
Affinity Capture-MS Homo sapiens
41 MRPS23 51649
Affinity Capture-MS Homo sapiens
42 MRPS5 64969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 HINT2 84681
Proximity Label-MS Homo sapiens
44 DUSP11  
Affinity Capture-MS Homo sapiens
45 MRPS24 64951
Affinity Capture-MS Homo sapiens
46 ZNF460  
Affinity Capture-MS Homo sapiens
47 NPM1 4869
Affinity Capture-MS Homo sapiens
48 KLF15  
Affinity Capture-MS Homo sapiens
49 RPS9 6203
Affinity Capture-MS Homo sapiens
50 MRPS26 64949
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 SURF1  
Proximity Label-MS Homo sapiens
52 TNFAIP8 25816
Cross-Linking-MS (XL-MS) Homo sapiens
53 PTCD1 26024
Affinity Capture-MS Homo sapiens
54 EXD2  
Proximity Label-MS Homo sapiens
55 TULP3 7289
Affinity Capture-MS Homo sapiens
56 ERAL1  
Affinity Capture-MS Homo sapiens
57 KLF4  
Affinity Capture-MS Homo sapiens
58 E4F1  
Affinity Capture-MS Homo sapiens
59 TIAL1 7073
Cross-Linking-MS (XL-MS) Homo sapiens
60 MRPS7 51081
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
61 PMPCB 9512
Proximity Label-MS Homo sapiens
62 TACO1  
Proximity Label-MS Homo sapiens
63 FASTKD2  
Proximity Label-MS Homo sapiens
64 PREPL 9581
Affinity Capture-MS Homo sapiens
65 VWA8 23078
Proximity Label-MS Homo sapiens
66 TEX14  
Cross-Linking-MS (XL-MS) Homo sapiens
67 RPL19 6143
Affinity Capture-MS Homo sapiens
68 MTERF3  
Proximity Label-MS Homo sapiens
69 GAR1 54433
Affinity Capture-MS Homo sapiens
70 LIN28A  
Affinity Capture-MS Homo sapiens
71 MDH2 4191
Proximity Label-MS Homo sapiens
72 TFB1M  
Affinity Capture-MS Homo sapiens
73 MRPS35 60488
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
74 C6orf203  
Proximity Label-MS Homo sapiens
75 COX15 1355
Proximity Label-MS Homo sapiens
76 FASTKD5  
Proximity Label-MS Homo sapiens
77 SRP14 6727
Affinity Capture-MS Homo sapiens
78 RPL4 6124
Affinity Capture-MS Homo sapiens
79 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 ERBB3 2065
Affinity Capture-MS Homo sapiens
81 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 POLRMT 5442
Affinity Capture-MS Homo sapiens
83 CPS1 1373
Affinity Capture-MS Homo sapiens
84 TUFM 7284
Proximity Label-MS Homo sapiens
85 ZBTB48  
Affinity Capture-MS Homo sapiens
86 SUGT1 10910
Affinity Capture-MS Homo sapiens
87 PTCD3 55037
Affinity Capture-MS Homo sapiens
88 HSCB 150274
Proximity Label-MS Homo sapiens
89 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
90 BTF3 689
Affinity Capture-MS Homo sapiens
91 MRPL18 29074
Affinity Capture-MS Homo sapiens
92 MRPS6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 CCDC109B 55013
Proximity Label-MS Homo sapiens
94 REXO4  
Affinity Capture-MS Homo sapiens
95 TBRG4 9238
Proximity Label-MS Homo sapiens
96 CBX6  
Affinity Capture-MS Homo sapiens
97 FBXL6  
Affinity Capture-MS Homo sapiens
98 DDX54 79039
Affinity Capture-MS Homo sapiens
99 NOA1  
Affinity Capture-MS Homo sapiens
100 RPS6 6194
Affinity Capture-MS Homo sapiens
101 MTFMT  
Proximity Label-MS Homo sapiens
102 MRPL11 65003
Proximity Label-MS Homo sapiens
103 MTRF1L  
Proximity Label-MS Homo sapiens
104 MAGEB2 4113
Affinity Capture-MS Homo sapiens
105 TMEM70  
Proximity Label-MS Homo sapiens
106 MRPS33  
Affinity Capture-MS Homo sapiens
107 GLTSCR2  
Affinity Capture-MS Homo sapiens
108 PDSS2  
Affinity Capture-MS Homo sapiens
109 MRPL2 51069
Affinity Capture-MS Homo sapiens
110 Brwd3  
Affinity Capture-MS Mus musculus
111 YBX3 8531
Affinity Capture-MS Homo sapiens
112 OTC 5009
Proximity Label-MS Homo sapiens
113 ZNF770 54989
Affinity Capture-MS Homo sapiens
114 MRRF  
Proximity Label-MS Homo sapiens
115 ABT1 29777
Affinity Capture-MS Homo sapiens
116 MRPS12  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 AURKAIP1  
Affinity Capture-MS Homo sapiens
118 MTIF2 4528
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 NR3C1 2908
Proximity Label-MS Homo sapiens
120 RC3H2  
Affinity Capture-MS Homo sapiens
121 RBM47 54502
Affinity Capture-MS Homo sapiens
122 YBX1 4904
Affinity Capture-MS Homo sapiens
123 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 MTIF3  
Proximity Label-MS Homo sapiens
125 RPL35 11224
Affinity Capture-MS Homo sapiens
126 PCDHB15  
Affinity Capture-MS Homo sapiens
127 SRSF5 6430
Affinity Capture-MS Homo sapiens
128 MRPL9 65005
Affinity Capture-MS Homo sapiens
129 MRPS14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 MRPL16  
Affinity Capture-MS Homo sapiens
131 SURF6  
Affinity Capture-MS Homo sapiens
132 RPUSD3  
Proximity Label-MS Homo sapiens
133 RMND1 55005
Proximity Label-MS Homo sapiens
134 GADD45GIP1  
Affinity Capture-MS Homo sapiens
135 DHX30 22907
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 KBTBD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 C17orf80 55028
Proximity Label-MS Homo sapiens
138 MRPS28  
Affinity Capture-MS Homo sapiens
139 C12orf65  
Proximity Label-MS Homo sapiens
140 MYCN  
Affinity Capture-MS Homo sapiens
141 PRR3  
Affinity Capture-MS Homo sapiens
142 MTG1  
Proximity Label-MS Homo sapiens
143 RPL17 6139
Affinity Capture-MS Homo sapiens
144 MYC  
Affinity Capture-MS Homo sapiens
145 PRKRIR  
Affinity Capture-MS Homo sapiens
146 NOL12 79159
Affinity Capture-MS Homo sapiens
147 TSFM 10102
Proximity Label-MS Homo sapiens
148 LSM11  
Affinity Capture-MS Homo sapiens
149 DAP3 7818
Affinity Capture-MS Homo sapiens
150 ACAD9 28976
Proximity Label-MS Homo sapiens
151 DDRGK1 65992
Affinity Capture-MS Homo sapiens
152 PCYOX1L 78991
Cross-Linking-MS (XL-MS) Homo sapiens
153 MRPS17 51373
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 METTL15  
Proximity Label-MS Homo sapiens
155 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 MCUR1 63933
Proximity Label-MS Homo sapiens
157 RBMS2 5939
Affinity Capture-MS Homo sapiens
158 DDX55  
Affinity Capture-MS Homo sapiens
159 FAM120A 23196
Affinity Capture-MS Homo sapiens
160 ZNF574  
Affinity Capture-MS Homo sapiens
161 RPL13 6137
Affinity Capture-MS Homo sapiens
162 CLPP 8192
Proximity Label-MS Homo sapiens
163 CS 1431
Proximity Label-MS Homo sapiens
164 ZNF707  
Affinity Capture-MS Homo sapiens
165 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
166 RIT1 6016
Negative Genetic Homo sapiens
167 RC3H1 149041
Affinity Capture-MS Homo sapiens
168 AUH 549
Proximity Label-MS Homo sapiens
169 MRPS2 51116
Affinity Capture-MS Homo sapiens
170 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
171 DNAJC19 131118
Proximity Label-MS Homo sapiens
172 MCAT 27349
Affinity Capture-MS Homo sapiens
173 TP53 7157
Affinity Capture-MS Homo sapiens
174 CEP76  
Affinity Capture-MS Homo sapiens
175 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
176 APOBEC3D  
Affinity Capture-MS Homo sapiens
177 LONP1 9361
Proximity Label-MS Homo sapiens
178 MRPS18C  
Affinity Capture-MS Homo sapiens
179 MRPS31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
181 MRPL28 10573
Affinity Capture-MS Homo sapiens
182 MRPS15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 MRPS10 55173
Affinity Capture-MS Homo sapiens
184 NSA2  
Affinity Capture-MS Homo sapiens
185 H2AFB3  
Affinity Capture-MS Homo sapiens
186 KIFAP3 22920
Affinity Capture-MS Homo sapiens
187 C21orf33  
Proximity Label-MS Homo sapiens
188 MKI67  
Affinity Capture-MS Homo sapiens
189 MRPS21  
Affinity Capture-MS Homo sapiens
190 SSBP1 6742
Proximity Label-MS Homo sapiens
191 PCNA 5111
Affinity Capture-MS Homo sapiens
192 KLF12  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 UFL1 23376
Affinity Capture-MS Homo sapiens
194 FASTKD3  
Proximity Label-MS Homo sapiens
195 MRPS18B 28973
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
197 GFM1 85476
Proximity Label-MS Homo sapiens
198 TEFM  
Proximity Label-MS Homo sapiens
199 MRPS9 64965
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
200 RPL7A 6130
Affinity Capture-MS Homo sapiens
201 MGME1  
Affinity Capture-MS Homo sapiens
202 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 TRMT10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 MRPS16  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
205 GRSF1 2926
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
206 C1QBP 708
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
207 RPL23A 6147
Affinity Capture-MS Homo sapiens
208 KRAS 3845
Negative Genetic Homo sapiens
209 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 RPL36AL 6166
Affinity Capture-MS Homo sapiens
211 METTL17  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
212 MRPS22 56945
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
213 SRSF7 6432
Affinity Capture-MS Homo sapiens
214 STRBP 55342
Affinity Capture-MS Homo sapiens
215 ZNF865  
Affinity Capture-MS Homo sapiens
216 DDX56  
Affinity Capture-MS Homo sapiens
217 SRSF3 6428
Affinity Capture-MS Homo sapiens
218 DDX28  
Proximity Label-MS Homo sapiens
219 HINT1 3094
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml



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