Gene description for PCYOX1L
Gene name prenylcysteine oxidase 1 like
Gene symbol PCYOX1L
Other names/aliases -
Species Homo sapiens
 Database cross references - PCYOX1L
ExoCarta ExoCarta_78991
Entrez Gene 78991
HGNC 28477
UniProt Q8NBM8  
 PCYOX1L identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for PCYOX1L
Molecular Function
    prenylcysteine oxidase activity GO:0001735 IBA
Biological Process
    prenylated protein catabolic process GO:0030327 IBA
    oxidation-reduction process GO:0055114 IBA
    prenylcysteine catabolic process GO:0030328 IBA
Subcellular Localization
    membrane GO:0016020 IDA
    vacuolar membrane GO:0005774 IBA
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified PCYOX1L in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for PCYOX1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PCYOX1L is involved
No pathways found





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