Gene description for EPDR1
Gene name ependymin related 1
Gene symbol EPDR1
Other names/aliases EPDR
MERP-1
MERP1
UCC1
Species Homo sapiens
 Database cross references - EPDR1
ExoCarta ExoCarta_54749
Vesiclepedia VP_54749
Entrez Gene 54749
HGNC 17572
UniProt Q9UM22  
 EPDR1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for EPDR1
Molecular Function
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    phospholipid binding GO:0005543 IPI
    identical protein binding GO:0042802 IDA
    ganglioside GM1 binding GO:1905573 IDA
Biological Process
    cell-matrix adhesion GO:0007160 IEA
    myofibroblast contraction GO:1990764 IMP
Subcellular Localization
    extracellular region GO:0005576 IDA
    lysosome GO:0005764 IBA
    lysosome GO:0005764 IDA
    lysosomal lumen GO:0043202 IEA
 Experiment description of studies that identified EPDR1 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for EPDR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FGFR3 2261
Affinity Capture-MS Homo sapiens
2 KNDC1  
Affinity Capture-MS Homo sapiens
3 MRPS27 23107
Affinity Capture-MS Homo sapiens
4 KIF24  
Affinity Capture-MS Homo sapiens
5 C8orf33 65265
Affinity Capture-MS Homo sapiens
6 TSHB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 PCDHGC5  
Affinity Capture-MS Homo sapiens
8 COX5B 1329
Affinity Capture-MS Homo sapiens
9 UBQLN4 56893
Two-hybrid Homo sapiens
10 OBFC1 79991
Affinity Capture-MS Homo sapiens
11 SOD1 6647
Affinity Capture-MS Homo sapiens
12 SCGB1D1  
Affinity Capture-MS Homo sapiens
13 ADSL 158
Affinity Capture-MS Homo sapiens
14 ELK3  
Affinity Capture-MS Homo sapiens
15 CABP7  
Affinity Capture-MS Homo sapiens
16 NF2 4771
Affinity Capture-MS Homo sapiens
17 SEMA3C 10512
Affinity Capture-MS Homo sapiens
18 ARF5 381
Affinity Capture-MS Homo sapiens
19 METRNL 284207
Affinity Capture-MS Homo sapiens
20 PLCD3 113026
Affinity Capture-MS Homo sapiens
21 TTC13  
Affinity Capture-MS Homo sapiens
22 TLR7  
Affinity Capture-MS Homo sapiens
23 SQSTM1 8878
Affinity Capture-MS Homo sapiens
24 IL17RA 23765
Affinity Capture-MS Homo sapiens
25 C1orf35  
Affinity Capture-MS Homo sapiens
26 C9orf40  
Affinity Capture-MS Homo sapiens
27 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 THSD4 79875
Affinity Capture-MS Homo sapiens
29 TINAG  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 HTRA3 94031
Affinity Capture-MS Homo sapiens
31 RNF7  
Affinity Capture-MS Homo sapiens
32 GYLTL1B 120071
Affinity Capture-MS Homo sapiens
33 ZNF212  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 PRR3  
Affinity Capture-MS Homo sapiens
35 SIRPD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 CCDC69 26112
Affinity Capture-MS Homo sapiens
37 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
38 FBXO2 26232
Affinity Capture-MS Homo sapiens
39 SUN2 25777
Affinity Capture-MS Homo sapiens
40 CHRD  
Affinity Capture-MS Homo sapiens
41 PCSK6 5046
Affinity Capture-MS Homo sapiens
42 IGF2R 3482
Affinity Capture-MS Homo sapiens
43 NAGA 4668
Affinity Capture-MS Homo sapiens
44 DUSP14 11072
Affinity Capture-MS Homo sapiens
45 GRB14 2888
Affinity Capture-MS Homo sapiens
46 P3H3 10536
Affinity Capture-MS Homo sapiens
47 ATP10D 57205
Affinity Capture-MS Homo sapiens
48 RUNDC3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 FGFR4 2264
Affinity Capture-MS Homo sapiens
50 OAF 220323
Affinity Capture-MS Homo sapiens
51 ENPP7 339221
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ARMCX3 51566
Affinity Capture-MS Homo sapiens
53 P3H4 10609
Affinity Capture-MS Homo sapiens
54 PRSS12 8492
Affinity Capture-MS Homo sapiens
55 RIPPLY3  
Affinity Capture-MS Homo sapiens
56 DDX28  
Affinity Capture-MS Homo sapiens
57 KLHL2 11275
Affinity Capture-MS Homo sapiens
58 FBXO6 26270
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which EPDR1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here