Gene description for GYLTL1B
Gene name glycosyltransferase-like 1B
Gene symbol GYLTL1B
Other names/aliases LARGE2
PP5656
Species Homo sapiens
 Database cross references - GYLTL1B
ExoCarta ExoCarta_120071
Vesiclepedia VP_120071
Entrez Gene 120071
HGNC 16522
MIM 609709
UniProt Q8N3Y3  
 GYLTL1B identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for GYLTL1B
Molecular Function
    protein binding GO:0005515 IPI
    glucuronosyltransferase activity GO:0015020 IBA
    glucuronosyltransferase activity GO:0015020 ISS
    glucuronosyltransferase activity GO:0015020 TAS
    manganese ion binding GO:0030145 TAS
    UDP-xylosyltransferase activity GO:0035252 TAS
    xylosyltransferase activity GO:0042285 IBA
    xylosyltransferase activity GO:0042285 ISS
Biological Process
    protein O-linked glycosylation GO:0006493 TAS
    protein O-linked mannosylation GO:0035269 IBA
    protein O-linked mannosylation GO:0035269 IDA
    muscle cell cellular homeostasis GO:0046716 ISS
Subcellular Localization
    Golgi membrane GO:0000139 TAS
    Golgi apparatus GO:0005794 IBA
 Experiment description of studies that identified GYLTL1B in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for GYLTL1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NRG1 3084
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 CCL3  
Affinity Capture-MS Homo sapiens
3 C7orf34  
Affinity Capture-MS Homo sapiens
4 GALNT10 55568
Affinity Capture-MS Homo sapiens
5 GPIHBP1  
Affinity Capture-MS Homo sapiens
6 HSPA5 3309
Affinity Capture-MS Homo sapiens
7 BTNL2  
Affinity Capture-MS Homo sapiens
8 EPDR1 54749
Affinity Capture-MS Homo sapiens
9 SCGB2A1 4246
Affinity Capture-MS Homo sapiens
10 CANX 821
Affinity Capture-MS Homo sapiens
11 HLA-G 3135
Affinity Capture-MS Homo sapiens
12 CLEC2B  
Affinity Capture-MS Homo sapiens
13 FRMD3  
Affinity Capture-MS Homo sapiens
14 TAZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 TMEM25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 LRRN2 10446
Affinity Capture-MS Homo sapiens
17 CLEC2D  
Affinity Capture-MS Homo sapiens
18 PLAUR 5329
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 PDGFRA 5156
Affinity Capture-MS Homo sapiens
20 RLN1  
Affinity Capture-MS Homo sapiens
21 IFNE  
Affinity Capture-MS Homo sapiens
22 B4GAT1 11041
Affinity Capture-MS Homo sapiens
23 MGAT4C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 GAA 2548
Affinity Capture-MS Homo sapiens
25 SFTPC  
Affinity Capture-MS Homo sapiens
26 CLEC12B  
Affinity Capture-MS Homo sapiens
27 EMR4P  
Affinity Capture-MS Homo sapiens
28 LYZL1  
Affinity Capture-MS Homo sapiens
29 SCGB1D4  
Affinity Capture-MS Homo sapiens
30 HLA-DQA1 3117
Affinity Capture-MS Homo sapiens
31 IDS  
Affinity Capture-MS Homo sapiens
32 SDF2L1 23753
Affinity Capture-MS Homo sapiens
33 C4orf26  
Affinity Capture-MS Homo sapiens
34 SCGB2A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 PSCA 8000
Affinity Capture-MS Homo sapiens
36 TCTN2  
Affinity Capture-MS Homo sapiens
37 CEACAM8 1088
Affinity Capture-MS Homo sapiens
38 HYOU1 10525
Affinity Capture-MS Homo sapiens
39 MPPE1 65258
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 IL17RC 84818
Affinity Capture-MS Homo sapiens
41 KLRC1  
Affinity Capture-MS Homo sapiens
42 BAGE2  
Affinity Capture-MS Homo sapiens
43 CFC1  
Affinity Capture-MS Homo sapiens
44 DKKL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 CST9L  
Affinity Capture-MS Homo sapiens
46 IGFL3  
Affinity Capture-MS Homo sapiens
47 ST8SIA4 7903
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GYLTL1B is involved
PathwayEvidenceSource
Metabolism of proteins TAS Reactome
O-linked glycosylation TAS Reactome
Post-translational protein modification TAS Reactome





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