Gene description for HLA-G
Gene name	major histocompatibility complex, class I, G
Gene symbol	HLA-G
Other names/aliases	MHC-G
Species	Homo sapiens
Database cross references - HLA-G
ExoCarta	ExoCarta_3135
Entrez Gene	3135
HGNC	4964
MIM	142871
UniProt	P17693
HLA-G identified in exosomes derived from the following tissue/cell type
Bladder cancer cells	20224111
Malignant pleural effusions	14975938

Gene ontology annotations for HLA-G

Molecular Function     peptide antigen binding GO:0042605 IBA     receptor binding GO:0005102 IPI     protein homodimerization activity GO:0042803 NAS Biological Process     interferon-gamma-mediated signaling pathway GO:0060333 TAS     antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 TAS     type I interferon signaling pathway GO:0060337 TAS     negative regulation of dendritic cell differentiation GO:2001199 IDA     antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0042590 TAS     cellular defense response GO:0006968 TAS     antigen processing and presentation of peptide antigen via MHC class I GO:0002474 TAS     positive regulation of T cell tolerance induction GO:0002666 IMP     positive regulation of regulatory T cell differentiation GO:0045591 IMP     positive regulation of tolerance induction GO:0002645 IMP     negative regulation of immune response GO:0050777 IC     immune response-inhibiting cell surface receptor signaling pathway GO:0002767 IDA     antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 TAS     negative regulation of T cell proliferation GO:0042130 IDA     cytokine-mediated signaling pathway GO:0019221 TAS     regulation of immune response GO:0050776 TAS     positive regulation of interleukin-12 production GO:0032735 IDA Subcellular Localization     early endosome membrane GO:0031901 TAS     membrane GO:0016020 IDA     MHC class I protein complex GO:0042612 IEA     integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 TAS     phagocytic vesicle membrane GO:0030670 TAS     Golgi membrane GO:0000139 TAS     plasma membrane GO:0005886 TAS     ER to Golgi transport vesicle membrane GO:0012507 TAS